Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Avoid alcohol since it may increase the depressive effect of Roxicet.1
• N-acetyl cysteine has been shown to improve liver damage caused by acetaminophen overdose.2
• Use of over three grams of vitamin C has been associated with decreased acetaminophen clearance time.3
• Herbs with sedative properties may intensify the effects of Roxicet and should not be used concurrently. These herbs include: calamus, calendula, chamomile, California poppy, catnip, couch grass, elecampane, ginseng Siberian, goldenseal, gotu kola, hops, Jamaican dogwood, kava, lemon balm, sage, St. John's wort, sassafras, scullcap, shepherd's purse, stinging nettle, valerian, withania root, and yerba mansa.4
References1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Vale JA, Proudfoot AT. Paracetamol (acetaminophen) poisoning. Lancet 1995;346:547-52.
3 Houston JB, Levy G. Drug biotransformation interactions in man. VI: Acetaminophen and ascorbic acid. J Pharm Sci 1976;65:121-21.
4 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
4 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
4 Facts and Comparisons, Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.