Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Avoid alcohol with this medication1
• The medication may interfere with sugar balance in diabetes; use with caution in diabetes.2
• This drug may be taken with food, it increases absorption of the drug.3
• Several studies done with olive oil, have shown it can reduce blood pressure. The dosage of antihypertensive medications may need to be reduced when olive oil is consumed on a regular basis.4
• CoQ10 may reduce blood pressure. If it is taken with this medication, a dosage adjustment may need to be made5
• Natural licorice products, Ginseng and Ephedra (Ma huang) may cause hypertension and should be avoided by those with high blood pressure6
• Some herbs possess diuretic properties that may intensify the action of antihypertensive drugs, which could result in an excessive lowering of blood pressure. Such herbs include Buchu, Butcher's Broom and Juniper.7
• These herbs may have cardiac properties that could intensify the effects of this drug. Some examples of these herbs are : black hellebore, calamus, cereus, cola, coltsfoot, devil's claw, European mistletoe, fenugreek, fumitory, digitalis leaf, hedge mustard, figwort, lily of the valley roots, motherwort, pleurisy root, squill bulb leaf scales, white horehound, mate, and shepherd's purse.8
References1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
1 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 Holt, G Food and Drug Interactions: Revised and Expanded Edition, Precept Press, 1998
3 Pronsky, Z Food Medication Interactions, 11th edition, 1999
4 Ruiz-Gutierrez V, Muriana FJ, Guerrero A, Cert AM, Villar J. Plasma lipids, erythrocyte membrane lipids and blood pressure of hypertensive women after ingestion of dietary oleic acid from two different sources. J Hypertens 1996 Dec;14(12):1483-90
4 Baroni SS, Amelio M, Sangiorgi Z, Gaddi A, Battino M. Solid monounsaturated diet lowers LDL unsaturation trait and oxidisability in hypercholesterolemic (type IIb) patients. Free Radic Res. 1999 Apr;30(4):275-85.
4 Ferrara LA, Raimondi AS, d'Episcopo L, et al. Olive oil and reduced need for antihypertensive medications. Arch Intern Med 2000;160(6):837-842.
5 Langsjoen P, Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med. 1994;15 Suppl:S265-72.
6 Farese, RV et al., Licorice-induced hypermineralcorticoidism. NEJM. 1991, 325:1,1223-1,227.
6 Pronsky, Z Food Medication Interactions, 11th edition, 1999
6 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
7 The Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
7 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
7 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
8 The Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
8 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
8 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.