Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Cephalosporins may contribute to the malabsorption of vitamins B and K with long term use.1
• Antibiotics kill bacteria, including beneficial flora in the gut. Supplementation with acidophilus or bifidus may aid in restoring the flora balance.2
• Avoid alcohol.3
• Avoid antacids with cephalosporins they may interfere with drug therapy.4
• Avoid feverfew, ginkgo and garlic with cephalosporins due to their blood thinning properties and known interactions with coumadin.5
References1 Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999.
1 Anonymous. New examples of vitamin K-drug interaction. Nutr Rev 1984;42(4):161-63 [review].
1 Hill MJ: Intestinal flora and endogenous vitamin synthesis, Eur J Cancer Prev, 1997, 6 (Suppl 1): S43-5.
1 Deguchi Y, et al: Comparitive studies on synthesis of water-soluble vitamins among human species of Bifidobacteria, Argic Biol Chem, 1985, 19 (1): 13-19.
1 Conly J and Stein K: Reduction of vitamin K2 concentrations in human liver associated with the use of broad spectrum antimicrobials, Clin Invest Med, 1994, 17 (6):531-9.
2 Bengmark S & Gianotti L: Nutritional support to prevent and treat multiple organ failure. World J Surg, 1996 May, 20:4, 474-81.
2 Cummings JH, Macfarlane G: Role of intestinal bacteria in nutrient metabolism, JPEN J Parenter Enteral Nutr, 1997, 21(6): 357-65.
2 Gorbach SL: Bengt E. Gustafsson Memorial Lecture, Function of the Normal Human Microflora, Scand J Infect Dis Suppl, 1986, 49:17-30.
3 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
4 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
5 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
5 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.