Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Use of alcohol should be avoided.1
• Vitamin C may be helpful in preventing nitrate tolerance. Discuss supplementation with a pharmacist.2
• These herbs may have cardioactive properties and should be avoided while using Nitrostat: black hellebore, calamus, cereus, cola, coltsfoot, devil's claw, European mistletoe, fenugreek, fumitory, digitalis leaf, hedge mustard, figwort, lily of the valley roots, motherwort, pleurisy root, squill bulb leaf scales, white horehound, mate, scotch broom flower, shepherd's purse, and wild carrot3
• Natural licorice products, Ginseng, and Ephedra (Ma huang) may cause hypertension, and should therefore be avoided by those with high blood pressure.4
References1 Drug Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
1 Allison, R. D. et al., Effects of alcohol and nitroglycerin in vascular responses in man. Angiology, 1971, 22: 211-222.
2 Watanabe H, et al. Randomized, double-blind, placebo-controlled study of the preventive effect of supplemental oral vitamin C on attenuation of development of nitrate tolerance. J Am Coll Cardiol 31(6) 1323-1329, 1998.
2 Bassenge E, et al. Dietary supplement with vitamin C prevents nitrate tolerance. J Clin Invest 31: 67-71, 1998.
3 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
3 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
4 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
4 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.