Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Lactic acidosis and other hepatic adverse reactions are possible with Epivir, monitor liver function carefully while on this medication.1
• The japanese herbal product Sho-saiko-to has been shown to increase the anti-HIV activity of Epivir invitro.2
• Laurelwood may have anti-HIV acitivity used with some AIDS drugs like Epivir.3
• Astragalus may interact with antiviral medications, increase side effects.4
• These herbs show antiviral properties according to the German Commission E: Cloves, Cardamom seed, White oak bark, Sage leaf. Theoretically, they may interfere with Epivir or other antiretroviral medications.5
References1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Piras G, Makino M, Baba M. Sho-saiko-to, a traditional Kampo medicine, enhances the anti-HIV-1 activity of lamivudine (3TC) in vitro. Microbiol Immunol 1997;41(10):835-9.
3 Currens MJ, Nariner JM, McMahon JB, Boyd MR. Kinetic analysis of inhibition of human immunodeficiency virus type-a reverse transcriptase by calanolide A. J Pharmacol Exp Ther 1996;279(2):652-661.
4 Upton R (ed). Astragalus Root: analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia; 1999;1-25
4 Facts and Comparisons, The Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
5 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998.
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.