Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Avoid alcohol.1
• Blocadren may contribute to deficiencies in choline, and CoQ10 with long term use. A quality multivitamin may be recommended by your physician or pharmacist.2
• Chromium may increase HDL cholesterol levels if used together with beta blockers.3
• These herbs may adversely affect the action of blocadren: black hellebore, calamus, cereus, cola, coltsfoot, devil's claw, European mistletoe, fenugreek, fumitory, digitalis leaf, hedge mustard, figwort, lily of the valley roots, motherwort, pleurisy root, squill bulb leaf scales, white horehound, mate, scotch broom flower, shepherd's purse, and wild carrot, due to their cardiac properties.4
• Natural licorice products, Ginseng and Ephedra (Ma huang) may cause hypertension and should be avoided with high blood pressure.5
• Cola, Guarana, Mate are some caffeine containing herbs that should be avoided with beta blockers.6
• Some herbs possess diuretic properties that may intensify the action of antihypertensive drugs, which could result in an excessive lowering of blood pressure. Such herbs include Buchu, Butcher's Broom and Juniper.7
References1 Mindell, E, Hopkins V: Prescription Alternatives. New Canaan, CT: Keats Publishing, Inc, 1998; p. 143.
1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Shand, D.G.: Clinical pharmacology of the beta-blocking drugs: implications for the postinfarction patient. Circulation, 1983, 67(Supp 1): 12-15.
2 Kishi H, Kishi T, Folkers K: Bioenergetics in clinical medicine III - inhibition of coenzyme Q10-enzymes by clinically used antihypertensive drugs, Res Commun Chem Pathol Pharmacol, 1975, 12(3):533-40.
3 Roeback JR Jr, Hla KM, Chambless LE, Fletcher RH. Effects of chromium supplementation on serum high-density lipoprotein cholesterol levels in men taking beta-blockers. A randomized, controlled trial. Ann Intern Med, 1991;115(12):917-924
4 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
4 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
4 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
5 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
5 The Review of Natural Products, Facts and Comparisons, Wolters Kluwer Company, 2000
5 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
6 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
7 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
7 The Review of Natural Products, Facts and Comparisons, Wolters Kluwer Company, 2000
7 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.