Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Alcohol can increase both the sedative and the intoxifying effects of Clonazepam. Use of alcohol should be avoided.1
• Avoid caffeine, including sodas, coffee, teas or chocolate. Supplements containing caffeine should also be avoided.2
• Tobacco may reduce the effectiveness of Clonazepam and should be avoided.3
• The following herbs have sedative qualities and could intensify the effects of Clonazepam: calamus, calendula, chamomile, California poppy, catnip, couch grass, elecampane, ginseng Siberian, goldenseal, gotu kola, hops, Jamaican dogwood, kava, lemon balm, sage, St. John's wort, sassafras, scullcap, shepherd's purse, stinging nettle, valerian, withania root, and yerba mansa.4
• The combination of Kava and Clonazepam may be dangerous and should not be used in combination without consulting a physician.5
References1 Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999
1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Rybacki, JJ. Concise Essential Guide to Prescription Drugs. HarperCollins, 1997.
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Ferguson, T: The Smokerís Book of Health, New York, 1987.
3 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
4 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
4 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
4 The Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
5 Davies LP, Drew CA, Duffield P, et al. Kava pyrones and resin: Studies on GABAA, GABAB and benzodiazepine binding sites in rodent brain. Pharm Toxicol 1992;71:120-26.
5 Holm E, Staedt U, Heep J, et al. Studies on the profile of the neurophysiological effects of D,L-kavain: Cerebral sites of action and sleep-wakefulness rhythm in animals. Arzneim Forsch 1991;41:673-83.
5 Almeida JC. Coma from the health food store: Interaction between kava and alprazolam. Ann Intern Med 1996;125:940-41.
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.