Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Premarin may affect absorption of B6, B12, folic acid, magnesium and zinc . Discuss the need for supplementation with long term use of the medication with a pharmacist.1
• Excess vitamin C may result in increased estrogen effects.2
• Talk to your doctor about calcium supplementation, exercise, periodic bone density screenings, and height measurement.3
• Avoid alcohol.4
• Avoid caffeine.5
• The following herbs may affect hormone levels: Agnus Castus, Black Cohosh, Bugleweed, Burning Bush, Dong Quai, Saw Palmetto, Shepherd's Purse, and Vervain.6
• Avoid cola, guarana, and mate due to their caffeine content with premarin.7
References1 Zava, DT: Estrogen and progestin bioactivity of foods, herbs and spices. Proc. Soc. Exp. Biol. Med. 1998, 217:369-378.
1 Adams PW, Wynn V, Rose DP, et al. Effect of pyridoxine hydrochloride (vitamin B6) upon depression associated with oral contraception. Lancet 1973;I:897-904.
1 Holt GA. Food & Drug Interaction. Chicago: Precept Press, 1998, 197-98.
1 Massé PG, van den Berg H, Duguay C, et al. Early effect of a low dose (30 mcg) ethinyl estradiol-containing Triphasil® on vitamin B6 status. Int J Vit Nutr Res 1996;66:46-54.
1 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Rybacki, JM. The Concise Guide to Prescription Drugs. Harper, 1997.
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Rybacki, JM. The Concise Guide to Prescription Drugs. Harper, 1997.
4 Pronsky, Z Food Medication Interactions, 11th edition, 1999
5 Pronsky, Z Food Medication Interactions, 11th edition, 1999
6 Ferguson T: The Smoker’s Book of Health, G.P. Putnam’s Sons, New York, 1987.
6 Threlkeld DS, ed. Hormones, Oral Contraceptives. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Jul 1994.
6 Zava, DT: Estrogen and progestin bioactivity of foods, herbs and spices. Proc. Soc. Exp. Biol. Med. 1998, 217:369-378.
6 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
6 Foster S, Tyler VE. Tyler's Honest Herbal, fourth ed., Binghamton, NY: Haworth Herbal Press, 1999.
7 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.