Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Take this medication separated from iron and folic acid supplements by at least two hours. Maalox can decrease the absorption of iron, zinc, phosphorous and folic acid. Long term use of this antacid is not recommended without a physician's advice.1
• Long term use of aluminum containing antacids may be harmful to health. Therefore, avoid using high doses of Maalox for more than 2 weeks without consulting a physician or pharmacist.2
• Avoid calcium citrate and other citrus fruits or juices within 2 to 3 hours of aluminum containing antacids like Maalox. Citrate can increase aluminum absorption.3
• Aluminum containing antacids, like Maalox can decrease calcium levels with long term use.4
• Long term use of some antacids can cause riboflavin loss. It is advisable to take antacids separated from supplements and food by at least 1 hour.5
References1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
1 Pronsky, Z Food Medication Interactions, 11th edition, 1999
1 Russell RM, Golner BB, Krasinski SD, et al. Effect of antacid and H2 receptor antagonists on the intestinal absorption of folic acid. J Lab Clin Med 112: 458-463, 1988.
1 Sturniolo GC, Montino MC, Rossetto L, et al. Inhibition of gastric acid secretion reduces zinc absorption in man. J Am Coll Nutr 10: 372-375, 1991.
2 Gaby AR. Aluminum: The ubiquitous poison. Nutr Healing 4: 3, 4, 11, 1997.
2 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 Anonymous. Preliminary findings suggest calcium citrate supplements may raise aluminum levels in blood, urine. Family Practice News 22: 74-75, 1992.
3 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Nolan CR, Califano JR, and Butzin CA. Influence of calcium acetate or calcium citrate on intestinal aluminum absorption. Kidney Int 38: 937-941, 1990.
3 Fairweather-Tait S, Hickson K, McGaw B, Redi M. Orange juice enhances aluminum absorption from antacid preparation. Eur J Clin Nutr 1994;48:71-73.
4 Spencer H and Kramer L Antacid-induced calcium loss. Arch intern Med 143: 657-658, 1983.
4 Greenson JK, et al. Gastric mucosal calcinosis. Calcified aluminum phosphate deposits secondary to aluminum-containing antacids or sucralfate therapy in organ transplant patients. Am J Surg Pathol. 1993 Jan;17(1):45-50.
4 Spencer H, Kramer L Osteoporosis, calcium requirement, and factors causing calcium loss. Clin Geriatr Med. 1987 May;3(2):389-402.
5 Feldman S, Hedrick W. Antacid effects of the gastrointestinal absorption of riboflavin. J Pharm Sci 1983 Feb; 72(2): 121-3
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.