Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Take Relafen with food to avoid stomach irritation. Food will increase the absorption of this medication.1
• Alcohol is an irritant to the gastrointestinal tract. Use of alcohol with this medication heightens the risk of gastric ulceration and bleeding.2
• Relafen may also hinder the absorption of folic acid and vitamin C. Daily supplementation is recommended.3
• Licorice might protect the stomach against NSAID damage.4
• These herbs have salicylate properties and may have additive effects or side effects with the NSAIDís: angelica, feverfew, meadowsweet, poplar, quassia, and willow.5
References1 Rybacki JJ. The Concise Essential Guide to Prescription Drugs. HarperCollins, 1997.
1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
1 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Graedon J, Graedon, T: The Peopleís Guide to Deadly Drug Interactions, 1995, p. 149.
2 Holt GA. Food & Drug Interactions. Chicago, Precept Press, 1998, 137-38.
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Roe DA: Drug-Induced Nutritional Deficiencies. 2nd ed. Westport, Conn: AVI Publ Co; 1985.
3 Hodges R. Nutrition in Medical Practice. Philadelphia: W. B. Saunders, 1980, 323-31 [review].
3 Baggott JE, Morgan SL, Ha T, et al: Inhibition of folate-dependent enzymes by nonsteroidal anti-inflammatory drugs, Biochem J, 1992, 282(pt 1):197-202.
4 Rees WDW, Rhodes J, Wright JE, et al, Effect of deglycyrrhizinated liquorice on Gastric Mucosal Damage by Aspirin. Scand J Gastroenterol. 14:605-607, 1979.
4 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
5 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998
5 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
5 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.