Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Imitrex may interact with the nutritional supplement 5-HTP, the precursor molecule of serotonin.1
• Limit alcohol intake with Imitrex.2
• Food decreases absorption rate by one hour but does not interfere with total absorption.3
• The herb Ginkgo Biloba may affect the cerebrovascular system and should not be used in combination with Imitrex.4
• Prolonged use of the following herbs: Aloe, Black Hellebore, Buckthorn, Chinese rhubarb, Frangula, Lily-of-the-Valley, Ma-Huang, and Strophanthus can cause arrythmias as a side effect and therefore, may potentiate the adverse reactions of Imitrex.5
References1 Cocks TM: Comparison of contractile responses to 5-hydroxytryptamine and sumatriptan in human isolated coronary artery: synergy with the thromboxane A2-receptor agonist, U46619. Br J Pharmacol, 1993 Sep, 110:1, 360-8.
2 Scott AK: Sumatriptan clinical pharmacokinetics. Clin Pharmacokinet, 1994 Nov, 27:5, 337-44.
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 Pronsky, Z Food Medication Interactions, 11th edition, 1999.
4 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
4 Facts and Comparisons, The Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
5 PDR (Physician's Desk Reference) for Herbal Medicines. Second edition. Medical Economics Company. Montvale, NJ. 2000: 205, 259.
5 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.