Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• The use of alcohol should be limited.1
• Atenolol may also contribute to deficiencies in choline, and CoQ10. A quality multivitamin may be recommended by your physician or pharmacist.2
• Calcium may interfere with the absorption of Atenolol. Consider taking calcium supplements separately from all medications.3
• Chromium supplements taken with beta blockers may raise HDL cholesterol levels.4
• These herbs may adversely affect the action of Atenolol: Blue Cohosh, Cola, Devil’s Claw, Ephedra, Ginseng, Goldenseal, Hawthorn, Motherwort, Parsley, Pleurisy Root, Shizandra, Shepherd’s Purse, Wild Carrot, and Wormseed. Their use should be avoided while taking atenolol.5
• Natural licorice products, Ginseng and Ephedra (Ma huang) may cause hypertension and should be avoided by those with high blood pressure.6
• Some herbs possess diuretic properties that may intensify the action of antihypertensive drugs, which could result in an excessive lowering of blood pressure. Such herbs include Buchu, Butcher's Broom and Juniper.7
• Cola, Guarana, Mate are some caffeine containing herbs that should be avoided with beta blockers.8
• Melatonin can reverse the sleep effects of propranolol and Atenolol.9
• Beta Blockers can help to prevent Yohimbe toxicity.10
References1 Mindell, E, Hopkins V: Prescription Alternatives. New Canaan, CT: Keats Publishing, Inc, 1998; p. 143.
1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Shand, D.G.: Clinical pharmacology of the beta-blocking drugs: implications for the postinfarction patient. Circulation, 1983, 67(Supp 1): 12-15.
2 Product Information: Inderal, propranolol hydrochloride. Wyeth-Ayerst Laboratories, PA. 1993.
2 Kishi H, Kishi T, Folkers K: Bioenergetics in clinical medicine III - inhibition of coenzyme Q10-enzymes by clinically used antihypertensive drugs, Res Commun Chem Pathol Pharmacol, 1975, 12(3):533-40.
3 The Medical Letter Handbook of Adverse Drug Interactions, 1995.
3 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 Pronsky, Z Food Medication Interactions, 11th edition, 1999
4 Roeback JR Jr, Hla KM, Chambless LE, Fletcher RH. Effects of chromium supplementation on serum high-density lipoprotein cholesterol levels in men taking beta-blockers. A randomized, controlled trial. Ann Intern Med, 1991;115(12):917-924
5 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
5 Brinker, Francis, N.D. Herb Contraindications and Drug Interactions, Eclectic Medical Publications. 1998
6 Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999
6 Farese, RV et al., Licorice-induced hypermineralcorticoidism. NEJM. 1991, 325:1,1223-1,227.
6 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
7 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
7 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
7 The Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
8 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
9 Stoschitzky K, Sakotnik A, Lercher P, et al. Influence of beta-blockers on melatonin release. Eur J Clin Pharmacol 1999;55(2):111-115
9 Van Den Heuvel CJ, Reid KJ, Dawson D. "Effect of atenolol on nocturnal sleep and temperature in young men: reversal by pharmacological doses of melatonin." Physiol Behav, Jun. 1997; 61(6):795-802
10 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.