Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Antibiotics kill "good " bacteria, including beneficial flora in the gut, this may affect digestion and/or elimination. Supplementation with acidophilus or bifidus may aid in restoring this flora.1
• Biaxin may hinder the absorption of some B vitamins and vitamin K. Supplementation may be beneficial with long term use of the medication.2
• Biaxin and other macrolide antibiotics interact with digitalis. Avoid their use together, due to increased risk of side effects.3
References1 Bengmark S & Gianotti L: Nutritional support to prevent and treat multiple organ failure. World J Surg, 1996 May, 20:4, 474-81.
1 Fuller R. Probiotics in human medicine. Gut 1991;32:439-42 [review].
1 Elmer GW, Surawicz CM, McFarland LV. Biotherapeutic agents. A neglected modality for the treatment and prevention of selected intestinal and vaginal infections. JAMA 1996;275:870-76.
1 Cummings JH, Macfarlane G: Role of intestinal bacteria in nutrient metabolism, JPEN J Parenter Enteral Nutr, 1997, 21(6): 357-65.
1 Gorbach SL: Bengt E. Gustafsson Memorial Lecture, Function of the Normal Human Microflora, Scand J Infect Dis Suppl, 1986, 49:17-30.
2 Mindell, E, Hopkins V: Prescription Alternatives. New Canaan, CT: Keats Publishing, Inc, 1998; p. 336.
2 Hill MJ: Intestinal flora and endogenous vitamin synthesis, Eur J Cancer Prev, 1997, 6 (Suppl 1): S43-5.
2 Deguchi Y, et al: Comparative studies on synthesis of water-soluble vitamins among human species of Bifidobacteria, Argic Biol Chem, 1985, 19 (1): 13-19.
2 Conly J and Stein K: Reduction of vitamin K2 concentrations in human liver associated with the use of broad spectrum antimicrobials, Clin Invest Med, 1994, 17 (6):531-9.
2 Ellenger P, et al: Production and release of nicotinamide by the intestinal flora in man, Nature, 1944, 154:270-271.
3 Bizjak ED, Mauro VF. Digoxin-macrolide drug interaction. Ann Pharmacother 1997; 31:1077-79.
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.