Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Mineral imbalances can create a dangerous effect on the body when combined with Lanoxin. High calcium levels and low potassium and magnesium levels can create a toxic effect. Low calcium levels can reduce the effectiveness of Lanoxin. Consult with your pharmacist or physician regarding supplementation of minerals.1
• Digoxin may deplete thiamine with long term use. Discuss supplementation with a pharmacist.2
• Avoid natural licorice products, which may cause low levels of potassium.3
• Avoid using lanoxin with the following herbs: black hellebore, calamus, cereus, cola, coltsfoot, devil's claw, European mistletoe, fenugreek, fumitory, digitalis leaf, hedge mustard, figwort, lily of the valley roots, motherwort, pleurisy root, squill bulb leaf scales, white horehound, mate, scotch broom flower, shepherd's purse, and wild carrot, due to their cardioactive properties.4
• Hawthorn can increase the effects of lanoxin. Consult your physician before using both the herb and the medication at the same time.5
References1 Drug Interaction Facts, Tatro, D.S., Editor (St Louis, MO, Facts and Comparisons, through July, 1995).
1 Whang R, Oei TO, Watanabe A. Frequency of hypomagnesiumia in hospitalized patients receiving digitalis. Arch Intern Med 1985;145:655-56.
1 Holt GA. Food & Drug Interactions. Chicago: Precept Press,1998, 94.
1 Landauer RA. Magnesium deficiency and digitalis toxicity. JAMA 1984;251:730 [letter/review].
1 Schwinger RH, Eromann E: Heart failure and electrolyte disturbances, Methods find Exp Clin Pharmacol, 1992, 14(4): 315-25.
1 Kupfer S, Kosovsky JD: Effects of cardiac glycosides on renal tubular transport of calcium, magnesium, inorganic phosphate and glucose in the dog, J of Clin Investig, 1965, 44:1143.
1 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Geriatric Nutrition, 3rd edition (Englewood Cliffs, NJ, Prentice-Hall Inc., 1992).
2 Zangen A, Botzer D, Zangen R, et al: Furosemide and digoxin inhibit thiamine uptake in cardiac cells, Eur J Pharmacol, 1998, 361 (1):151-5.
3 Mindell, E, Hopkins V: Prescription Alternatives. New Canaan, CT: Keats Publishing, Inc, 1998; p. 107.
3 Tyler VE. The Honest Herbal, 3rd ed. New York: Pharmaceutical Products Press, 1993, 198.
3 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
4 Brinker, Francis: Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
4 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998.
4 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
5 Brinker, Francis: Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
5 Blumenthal M, ed. The Complete German Commission E Monographs. Austin, TX: American Botanical Council, 1998
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.