Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Take Daypro with food to avoid stomach irritation.1
• Alcohol is an irritant to the gastrointestinal tract. Use of alcohol with this medication heightens the risk of gastric ulceration and bleeding.2
• Damage to the gastrointestinal tract caused by NSAIDS like Daypro, may lead to iron loss. Monitor for signs/symptoms of damage.3
• Daypro may also hinder absorption of folic acid and vitamin C. Supplementation may be helpful.4
• Licorice might protect the stomach against NSAID damage.5
• These herbs have blood thinning properties and may have additive effects or side effects with the NSAIDís: Angelica, anise, arnica, asafoetida, bogbean, boldo, danshen, fenugreek, feverfew, garlic, ginger, ginkgo, ginseng (Panax), horse chestnut, licorice, meadowsweet, prickly ash, passionflower, poplar, quassia, red clover, turmeric, and willow.6
References1 Hydacki JJ. The Concise Essential Guide to Prescription Drugs. HarperCollins, 1997.
1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000.
2 Graedon J, Graedon, T: The Peopleís Guide to Deadly Drug Interactions, 1995.
2 Holt GA. Food & Drug Interactions. Chicago, Precept Press, 1998
2 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 Roe DA: Drug-Induced Nutritional Deficiencies. 2nd ed. Westport, Conn: AVI Publ Co; 1985.
3 Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998
3 Collins AJ, Reid J, Soper CJ, et al: Characteristics of ulcers of the small bowel induced by nonsteroidal anti-inflammatory drugs in the rat - implications for clinical practice, Br J Rheumatol, 1995, 34(8):727-31.
4 Roe DA: Drug-Induced Nutritional Deficiencies. 2nd ed. Westport, Conn: AVI Publ Co; 1985.
4 Hodges R. Nutrition in Medical Practice. Philadelphia: W. B. Saunders, 1980.
4 Baggott JE, Morgan SL, Ha T, et al: Inhibition of folate-dependent enzymes by nonsteroidal anti-inflammatory drugs, Biochem J, 1992, 282(pt 1):197-202.
5 Rees WDW, Rhodes J, Wright JE, et al, Effect of deglycyrrhizinated liquorice on Gastric Mucosal Damage by Aspirin. Scand J Gastroenterol. 14:605-607, 1979.
5 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
6 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
6 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998
6 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
6 The Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.