Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Limit or avoid caffeine, this medication decreases the metabolism of caffeine.1
• Avoid tryptophan supplements2
• Avoid St. John's Wort, may increase side effects, (serotonin-syndrome).3
• These herbs have sedative properties which may increase the CNS side effects of luvox: calamus, calendula, chamomile, California poppy, catnip, couch grass, elecampane, ginseng Siberian, goldenseal, gotu kola, hops, Jamaican dogwood, kava, lemon balm, sage, St. John's wort, sassafras, scullcap, shepherd's purse, stinging nettle, valerian, withania root, and yerba mansa.4
• Tobacco can increase the metabolism of fluvoxamine by 25%.5
• Melatonin may help improve sleep used together with these agents in depressed individuals. Discuss supplementation with a pharmacist.6
• Avoid cola, cocoa, guarana and mate due to their caffeine content while on this medication.7
References1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
1 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
3 Gordon JB. SSRIs and St. John's wort: possible toxicity? Am Fam Physician 1998;57:950.
3 Demott K. St. Johnís wort tied to serotonin syndrome. Clin Psychiatr News 1998;26:28
4 Fleishaker JC et al. A pharmacokinetic and pharmacodynamic evaluation of the combined administration of alprazolam and fluvoxamine. Eur J Clin Pharmacol 1994;46:35
4 Facts and Comparisons, Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
4 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
5 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
5 Pronsky, Z Food Medication Interactions, 11th edition, 1999
6 Dolberg OT, Hirschmann S, Grunhaus L. "Melatonin for the treatment of sleep disturbances in major depressive disorder." Am J Psychiatry, Aug. 1998; 155(8):1119-121.
7 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.