Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Food decreases absorption rate by one hour but does not interfere with total absorption.1
• Maxalt may interact with the nutritional supplement 5-HTP, the precursor molecule of serotonin.2
• Limit alcohol intake with Maxalt.3
• Prolonged use of the following herbs: Black Hellebore, Buckthorn, Cascara sagrada, Chinese rhubarb, Frangula, Lily-of-the-Valley, Ma-Huang, and Strophanthus can cause arrythmias as a side effect and therefore, may potentiate the adverse reactions of Maxalt.4
• Avoid using St. John's Wort with this drug. Concomitant use may enhance risk of adverse effects.5
References1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
1 Pronsky, Z Food Medication Interactions, 11th edition, 1999.
2 Cocks TM: Comparison of contractile responses to 5-hydroxytryptamine and sumatriptan in human isolated coronary artery: synergy with the thromboxane A2-receptor agonist, U46619. Br J Pharmacol, 1993 Sep, 110:1, 360-8.
3 Scott AK: Sumatriptan clinical pharmacokinetics. Clin Pharmacokinet, 1994 Nov, 27:5, 337-44.
3 Pronsky, Z Food Medication Interactions, 11th edition, 1999
4 PDR (Physician's Desk Reference) for Herbal Medicines. Second edition. Medical Economics Company. Montvale, NJ. 2000: 205, 259.
4 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
4 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998
5 Brandes JL, Edvinsson L, Marcus D, et al. New treatment options for migraine. Medscape Neurology Treatment Updates 2000.
5 Lantz MS, Buchalter E, Giambanco V. St John's Wort and antidepressant drug interactions in the elderly. J Geriatr Psychiatry Neurol. 1999 Spring;12(1):7-10.
5 Pronsky, Z Food Medication Interactions, 11th edition, 1999
Want more special reports like this e-mailed to you when they're available? Click here for free e-mail alerts.
Share this Special Report by linking to it
Copy and paste the following HTML code into any web page:
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.