Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Consume adequate amounts of fluids, unless otherwise directed.1
• Antibiotics kill bacteria, including beneficial flora in the gut, which may affect digestion and/or elimination. Supplementation with acidophilus and/or bifidus may help to replace this beneficial flora.2
• Avoid caffeine.3
• Calcium, magnesium, aluminum, zinc may reduce absorption and hence the effectiveness of fluoroquinolone antibiotics. Avoid consuming dairy products and/or supplements containing calcium at least two hours after ingesting this medication.4
• Avoid cola, cocoa, guarana and mate due to their caffeine content. Quinolones may decrease caffeine clearance.5
References1 Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999
2 Bengmark S & Gianotti L: Nutritional support to prevent and treat multiple organ failure. World J Surg, 1996 May, 20:4, 474-81.
2 Cummings JH, Macfarlane G: Role of intestinal bacteria in nutrient metabolism, JPEN J Parenter Enteral Nutr, 1997, 21(6): 357-65.
2 Gorbach SL: Bengt E. Gustafsson Memorial Lecture, Function of the Normal Human Microflora, Scand J Infect Dis Suppl, 1986, 49:17-30.
3 Carb- M, et al. "Effect of quinolones on caffeine disposition." Clin Pharmacol Ther, 1989; 45:234-40.
3 Healy DP, et al. "Interaction between oral ciprofloxacin and caffeine in normal volunteers." Antimicrob Agents Chemother, 1989; 33:474-78.
4 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
4 Lim D and McKay M. Food-drug interactions. Drug Information Bulletin (UCLA Dept. of Pharmaceutical Services) 15(2): 1995.
5 Carb- M, et al. "Effect of quinolones on caffeine disposition." Clin Pharmacol Ther, 1989; 45:234-40.
5 Healy DP, et al. "Interaction between oral ciprofloxacin and caffeine in normal volunteers." Antimicrob Agents Chemother, 1989; 33:474-78.
5 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.