diabetes

Diabetes drug researcher admits drug trials are unethical and dangerous

Monday, October 25, 2010 by: David Gutierrez, staff writer
Tags: drug trials, diabetes, health news

eTrust Pro Certified

Most Viewed Articles
Popular on Facebook
BACK INTO THE CLOSET: Why U.S. reporters are not allowed to write about rainbow events in nations where being gay is still condemned
Depopulation test run? 75% of children who received vaccines in Mexican town now dead or hospitalized
A family destroyed: Six-month-old dies after clinic injects baby with 13 vaccines at once without mother's informed consent
Biologist explains how marijuana causes tumor cells to commit suicide
U2's Bono partners with Monsanto to destroy African agriculture with GMOs
Companies begin planting microchips under employees' skin
BAM! Chipotle goes 100% non-GMO; flatly rejecting the biotech industry and its toxic food ingredients
ECONOMIC SLAVERY FOR ALL: While we were distracted with the Confederate flag flap, Congress quietly forfeited our entire economic future via fast-track trade authority
NJ cops bust teenagers shoveling snow without a permit
Russia throws down the gauntlet: energy supply to Europe cut off; petrodollar abandoned as currency war escalates
McDonald's in global profit free fall as people everywhere increasingly reject chemically-altered toxic fast food
March Against Monsanto explodes globally... World citizens stage massive protests across 38 countries, 428 cities... mainstream media pretends it never happened
Chemotherapy kills cancer patients faster than no treatment at all
600 strains of an aerosolized thought control vaccine already tested on humans; deployed via air, food and water
Italian court rules mercury and aluminum in vaccines cause autism: US media continues total blackout of medical truth
SCOTUS same-sex marriage decision may have just legalized the concealed carry of loaded firearms across all 50 states, nullifying gun laws everywhere
The 21 curious questions we're never allowed to ask about vaccines
Vicious attack on Dr. Oz actually waged by biotech mafia; plot to destroy Oz launched after episode on glyphosate toxicity went viral
Delicious
(NaturalNews) A drug researcher who presided over the trial that first raised concerns over the diabetes blockbuster Avandia has warned that further tests of the drug's safety would be unethical.

In 2009, David Juurlink of Sunnybrook Health Sciences Center in Toronto was the lead author of a study that compared rates of heart failure and death among older diabetics taking Avandia (known generically as rosiglitazone) and those taking Actos (pioglitazone), another drug in the same family. That study found that patients taking Avandia were 30 percent more likely to suffer heart failure or death.

Now Juurlink has joined with Sidney Wolfe, director of health research for Public Citizen, to call for the cancellation of another planned Avandia-Actos comparison study, known as the Thiazolidinedione Intervention in Vitamin D Evaluation (TIDE) trial.

The TIDE trial is to be performed by Avandia manufacturer GlaxoSmithKline at the behest of the FDA, which in 2007 ordered the company to conduct further safety studies of the drug. The FDA's order came after it required the company to put a "black box" warning on the drug's packaging about the risk of heart attack and heart failure.

The strong results of the 2009 study make any further comparison unethical, Juurlink and Wolfe have warned. The TIDE trial would expose "thousands of high-risk patients with diabetes to a drug with an unfavorable safety profile and clinical advantage over its comparator," they wrote in an open letter to the FDA.

The TIDE study is due to be carried out in 14 different countries, including Third World countries such as Chile, India, Latvia, Mexico and Pakistan.

"[The] price of definitive proof" that Avandia is unsafe, "will almost certainly be measured in the lives of study subjects who have been incompletely informed about the risks and benefits of participation," Wolfe and Juurlink wrote.

All drugs in the thiazolidinedione class, including Actos and Avandia, have also been linked to increased risk of anemia, edema, macular edema, bony fractures and acute liver injury.

Sources for this story include: http://latimesblogs.latimes.com/booster_shot....

Join over four million monthly readers. Your privacy is protected. Unsubscribe at any time.
comments powered by Disqus
Take Action: Support NaturalNews.com by linking back to this article from your website

Permalink to this article:

Embed article link: (copy HTML code below):

Reprinting this article:
Non-commercial use OK, cite NaturalNews.com with clickable link.

Follow Natural News on Facebook, Twitter, Google Plus, and Pinterest

Colloidal Silver

Advertise with NaturalNews...

Support NaturalNews Sponsors:

Advertise with NaturalNews...

GET SHOW DETAILS
+ a FREE GIFT

Sign up for the FREE Natural News Email Newsletter

Receive breaking news on GMOs, vaccines, fluoride, radiation protection, natural cures, food safety alerts and interviews with the world's top experts on natural health and more.

Join over 7 million monthly readers of NaturalNews.com, the internet's No. 1 natural health news site. (Source: Alexa.com)

Your email address *

Please enter the code you see above*

No Thanks

Already have it and love it!

Natural News supports and helps fund these organizations:

* Required. Once you click submit, we will send you an email asking you to confirm your free registration. Your privacy is assured and your information is kept confidential. You may unsubscribe at anytime.