Berberine a “multipotent” therapy for reducing risk of Alzheimer’s disease
02/25/2020 // Evangelyn Rodriguez // Views

Researchers from Hong Kong and Macau conducted a systematic review to evaluate the neuroprotective effects of berberine. Their article was published in the journal BMC Complementary and Alternative Medicine.

  • Alzheimer's disease (AD) is a complex disease driven by multiple factors.
  • Therapeutic strategies based on decreasing the amount of B-amyloid in the brain have failed in clinical trials, suggesting that AD therapy should not be focused on addressing a single cause, but rather a number of different pathways that lead to the disease.
  • Berberine, an alkaloid derived from various Berberis species, is widely used in East Asia to treat a wide range of health problems.
  • Recently, studies have reported that berberine has neuroprotective effects on AD animal models.
  • However, no clinical trial has been carried out to test these effects.
  • For their pre-clinical trial review, the researchers searched five online databases for publications reporting effect of berberine treatment on animal models of AD.
  • They found 15 papers published no later than March 18 that fit their criteria.
  • After analyzing data from those studies, the researchers reported that in multiple animal models with memory defects, berberine showed significant memory-improving activities.
  • These activities were mediated by different properties, including anti-inflammatory, antioxidant, cholinesterase-inhibiting and anti-amyloid activities.

Based on their findings, the researchers concluded that berberine is a promising multi-potent agent against Alzheimer's disease.

Read the full study at this link.

Journal Reference:

Yuan NN, Cai CZ, Wu MY, Su HX, Li M, Lu JH. NEUROPROTECTIVE EFFECTS OF BERBERINE IN ANIMAL MODELS OF ALZHEIMER’S DISEASE: A SYSTEMATIC REVIEW OF PRE-CLINICAL STUDIES. BMC Complementary and Alternative Medicine. 23 May 2019;19(1). DOI: 10.1186/s12906-019-2510-z



Take Action:
Support Natural News by linking to this article from your website.
Permalink to this article:
Copy
Embed article link:
Copy
Reprinting this article:
Non-commercial use is permitted with credit to NaturalNews.com (including a clickable link).
Please contact us for more information.
Free Email Alerts
Get independent news alerts on natural cures, food lab tests, cannabis medicine, science, robotics, drones, privacy and more.
App Store
Android App
eTrust Pro Certified

This site is part of the Natural News Network © 2022 All Rights Reserved. Privacy | Terms All content posted on this site is commentary or opinion and is protected under Free Speech. Truth Publishing International, LTD. is not responsible for content written by contributing authors. The information on this site is provided for educational and entertainment purposes only. It is not intended as a substitute for professional advice of any kind. Truth Publishing assumes no responsibility for the use or misuse of this material. Your use of this website indicates your agreement to these terms and those published here. All trademarks, registered trademarks and servicemarks mentioned on this site are the property of their respective owners.

This site uses cookies
Natural News uses cookies to improve your experience on our site. By using this site, you agree to our privacy policy.
Learn More
Close
Get 100% real, uncensored news delivered straight to your inbox
You can unsubscribe at any time. Your email privacy is completely protected.