Longjack can stimulate bone formation by improving expression of mitogenic proteins
05/09/2019 // Michelle Simmons // Views

In this study, researchers from the National University of Malaysia investigated the bone-forming ability of longjack (Eurycoma longifolia) and its potential as a natural treatment for osteoporosis in men. Their results were published in the Journal of Ayurveda and Integrative Medicine.

  • Longjack has attracted the interest of scientists because of its ability to stimulate bone formation in androgen-deficient osteoporosis.
  • The researchers examined the mechanisms behind longjack's ability to form bones using an in vitro osteoblastic model.
  • They compared longjack treatment with testosterone replacement, one of the standard treatments used for androgen-deficient osteoporosis.
  • The researchers found that treatment with longjack extract at a dose of 25 micrograms per milliliter (ug/mL) significantly increased cell growth, alkaline phosphatase activity, and collagen deposition and mineralization.
  • To determine the mechanisms behind its bone-forming activity, they also analyzed the time-mannered expression of bone-related mediators, such as bone morphogenic protein-2 (BMP-2), ALP, runt-related transcription factor-2 (Runx-2), osteocalcin, type I collagen, osteopontin, transforming growth factor-beta1 (TGF-beta1), and androgen receptor.
  • Their analysis of bone-related protein biomarkers revealed that the expression of these mediators was well-regulated in longjack-treated cell cultures compared with the control groups.

The findings of this study suggest that longjack can be considered as a potential alternative to conventional treatments used to address osteoporosis in men.

Read the full text of the study at this link.

Visit AlternativeMedicine.news to learn more about natural treatments for bone diseases.

Journal Reference:

Thu HE, Mohamed IN, Hussain Z, Shuid AN. EXPLORING MOLECULAR MECHANISM OF BONE-FORMING CAPACITY OF EURYCOMA LONGIFOLIA: EVIDENCE OF ENHANCED EXPRESSION OF BONE-RELATED BIOMARKERS. Journal of Ayurveda and Integrative Medicine. 2018; 9(4): 272-280. DOI: 10.1016/j.jaim.2017.04.005

Take Action:
Support Natural News by linking to this article from your website.
Permalink to this article:
Embed article link:
Reprinting this article:
Non-commercial use is permitted with credit to NaturalNews.com (including a clickable link).
Please contact us for more information.
Free Email Alerts
Get independent news alerts on natural cures, food lab tests, cannabis medicine, science, robotics, drones, privacy and more.
App Store
Android App
eTrust Pro Certified

This site is part of the Natural News Network © 2022 All Rights Reserved. Privacy | Terms All content posted on this site is commentary or opinion and is protected under Free Speech. Truth Publishing International, LTD. is not responsible for content written by contributing authors. The information on this site is provided for educational and entertainment purposes only. It is not intended as a substitute for professional advice of any kind. Truth Publishing assumes no responsibility for the use or misuse of this material. Your use of this website indicates your agreement to these terms and those published here. All trademarks, registered trademarks and servicemarks mentioned on this site are the property of their respective owners.

This site uses cookies
Natural News uses cookies to improve your experience on our site. By using this site, you agree to our privacy policy.
Learn More
Get 100% real, uncensored news delivered straight to your inbox
You can unsubscribe at any time. Your email privacy is completely protected.