Myositis or muscle inflammation refers to a condition where the muscles you use to move your body become inflamed. There are currently two known types: polymyositis and dermatomyositis. Polymyositis is characterized by feelings of weakness, usually in the muscles close to the body's trunk. Dermatomyositis has the same symptoms but is accompanied by a skin rash.
Infections, injuries, and chronic diseases are among the most common causes of muscle inflammation. The study focused on autoimmune disease, which occurs when the immune system attacks healthy cells instead of pathogens. In the case of myositis, the immune cells kill the cells that make up the muscles.
To cope with the condition, sufferers are prescribed several medications, including corticosteroids. Like many other chemical medications, corticosteroids are known to cause various side effects. These include bruising, weight gain, hypertension, and an increased risk of glaucoma and cataracts, among many others.
Moreover, Kanneboyina Nagaraju, a professor of pharmaceutical sciences at Binghamton University and co-author of the study, said myositis medications only do half the job. While they do manage to soothe the pain and attenuate the action of immune cells, they do not aid in the recovery of dying muscle cells.
“Yet, exercise takes care of the immune cells that are killing the muscles, and repairs the cell death of the muscle,” he said.
Nagaraju and an international team of researchers conducted an experiment using two groups of participants: a 12-week endurance exercise group and a non-exercise group. Their goal included determining how endurance exercise changes skeletal muscle microRNA. To determine any alteration in the participants' muscles, their muscle biopsies were recorded before and after exercise.
The researchers found that exercise changed the microRNAs that downregulate immune processes while decreasing the microRNAs that upregulate mitochondrial content. What this means is that exercise not only decreases the population of immune cells attacking muscle tissue, it also heals the muscles by raising aerobic metabolism in the mitochondria. (Related: Yoga can increase blood flow, aiding in repair and regeneration of tissue.)
“The results weren’t surprising,” Nagaraju said. “The reason why exercise wasn’t considered before is that if people have muscles that are already inflamed or weak, they believed exercise would make the muscles worse. However, what is surprising is the question of why exercise is so effective. It’s because exercise takes care of the immune cells that are damaging the muscle while simultaneously targeting specific parts of dead or affected muscles.”
He believes that their findings can help in the creation of more effective measures to counter muscle inflammation.
If you suffer from symptoms of myositis, there are ways to get comfort even without medication. Here are some remedies you can easily find at home:
Find useful remedies for muscle inflammation at Remedies.news.