• The anti-glioma effect of the Chinese goldthread was determined using six different measurements.

  • 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) method
  • Plate clone test
  • Scratch tests
  • Flow cytometry
  • Western blotting
  • Glioma xenograft tumor model

• All six tests showed that the Chinese goldthread suppressed glioma cell proliferation, tumor formation, migration, and tumor growth, and prolonged the survival time of glioma cell-bearing mice.
• Chinese goldthread was found to induce apoptosis in glioma cells while down-regulating essential transcription processes in malignant tumors.

Chinese goldthread effectively inhibited various functions of cancerous glial cells. These results suggest the herb's potential use in treating brain cancer caused by glioma.

Read the full text of this study at this link.

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Journal reference

Li, J., Ni, L., Li, B., Wang, M., Ding, Z., Xiong, C., and Lu, X. COPTIS CHINENSIS AFFECTS THE FUNCTION OF GLIOMA CELLS THROUGH THE DOWN-REGULATION OF PHOSPHORYLATION OF STAT3 BY REDUCING HDAC3; BMC Complementary and Alternative Medicine; 2017, 17:524; DOI: https://doi.org/10.1186/s12906-017-2029-0