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Aqueous curcumin

IV injection of aqueous curcumin inhibits colon cancer growth and kills cancer cells, research reveals

Monday, December 09, 2013 by: PF Louis
Tags: aqueous curcumin, colon cancer, IV injection

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(NaturalNews) Before you become dismayed wondering how the heck you can take advantage of this specially prepared solution injected intravenously (IV) in the land of the medically unfree, continue on for the good news later in this article after the study is explained.

This preparation may not have to be injected, thanks to LET (liposomal encapsulation technology), which started with vitamin C that replicated mega-dose IV C clinical results orally with smaller amounts, as in the case of Alan Smith in New Zealand, who completely recovered from a coma using LivOn Lab's Lypo-Spheric vitamin C packets after the hospital restricted his IV C dosage (http://www.naturalnews.com).

More on these oral solutions later. Now let's go over an interesting Chinese study conducted in 2011 on the effect of a uniquely derived delivery system with curcumin for cancer entitled "Curcumin loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo." (Source [1])

In vitro literally means "in glass" and in vivo means in an alive creature of some sort. So they did both test tube and live animal experiments. Those live animals are usually mice or lab rats because of their genetic and other similarities to humans. This time, they used transgenic zebrafish, yes, the kind sold out of pet store fresh water aquariums.

It seems that enough genome similarity to lab rats and humans has been discovered with zebrafish recently. And researchers in the USA are using them also, especially for studying disease while looking for cures. Their genomes are easily manipulated to simulate human diseases. (Source [2])

Transgenic indicates that some sort of gene was inserted. In this case, it was probably the colon cancer genes. That's the cancer on which they decided to try this micelle-encapsulated curcumin. It's similar to liposomal encapsulation but slightly different in composition. The principle of encapsulating is the same.

It's to enable what is normally broken down by digestive processes to continue into the blood stream and, more importantly, penetrate lipid cell walls that are resistant to liquid penetration using nanotechnology that creates supplement nanoparticles encapsulated in tiny lipid particles.

Here's how Avanti Polar Lipids describes the difference: "Liposomes are composed of a lipid bilayer separating an aqueous internal compartment from the bulk aqueous phase. Micelles are closed lipid monolayers with a fatty acid core and polar surface, or polar core with fatty acids on the surface (inverted micelle)." Both serve the same function. Okay, you can wake up now.

The researchers observed dramatic reductions of angiogenesis, or blood vessels forming to support cancer tumors, in vivo, and they observed cancer cells killed in vitro.

Thus the Chinese study concluded that "micelles are an excellent intravenously injectable aqueous formulation of curcumin; this formulation can inhibit the growth of colon carcinoma through inhibiting angiogenesis and directly killing cancer cells." [1]

So now for even better news. It appears that the LET industry has expanded considerably beyond liposomal C to include liposomal curcumin that's as effective orally as it is injected or through IV. You can view a whole bunch of them from source [3].

So, since liposomal vitamin C is more effective at getting vitamin C into cells than even IV mega-dose vitamin C, it's reasonable to assume that oral liposomal curcumin is at least as effective as injected micelles curcumin.

As a matter of fact, an even more recent 2013 study in Texas, USA, determined high efficacy without side effects using liposomal curcumin on normally treatment-resistant pancreatic cancer. Their studies were both in vitro and in vivo, and the in vivo models were mice instead of zebrafish. Check it out at source [4].

Curious about DIY liposomal encapsulated technology (LET)? Go to source [5] for starters.

Source for this article include:


[2] http://www.nature.com

[3] www.google.com

[4] http://www.ncbi.nlm.nih.gov

[5] www.google.com

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