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Alpha-lopoic acid

Controlled-Release Alpha-Lipoic Acid Introduced for Diabetics (press release)

Wednesday, April 06, 2005
by Mike Adams, the Health Ranger
Editor of NaturalNews.com (See all articles...)
Tags: alpha-lopoic acid, diabetes, nutritional supplements


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The First and Only Proprietary, Controlled-Release Formulation of Alpha-Lipoic Acid Reduces Oxidative Stress Associated with Diabetes by Antagonizing Excessive Free Radicals at the Cellular Level

Medical Research Institute (MRI), an innovator in nutraceutical approaches for diabetes, today announced the availability of Glucotize(TM), the only patented (three US patents awarded; additional applications filed), controlled-release formulation of the safe and effective antioxidant alpha-lipoic acid. Extensive research and clinical experience have indicated that alpha-lipoic acid is safe, well tolerated, and effective in providing symptomatic relief of diabetic neuropathy. Most recently, results from a collaborative study between groups from the Mayo Clinic and the Russian Medical Academy reported that alpha-lipoic acid rapidly and significantly reduced the frequency and severity of symptoms from diabetic polyneuropathy (Ametov et al Diabetes Care 2003 26:770-6).

More recently, alpha-lipoic acid has been reported to improve whole-body glucose metabolism and insulin sensitivity in individuals with type 2 diabetes, which if confirmed in larger studies, could help in the prevention and treatment of type 2 diabetes along with other conditions associated with impaired glucose metabolism. Intravenous infusions of ALA have been used with outstanding results by physicians in Germany for more than 25 years to treat neuropathy, a common diabetic complication, and one that causes significant pain and discomfort.

While other manufacturers offer alpha-lipoic acid, it is not controlled release, a limitation that means alpha-lipoic acid is eliminated from the body very quickly -- in as little as 30 minutes -- significantly hampering its efficacy. MRI's Glucotize(TM) is a unique oral formulation whose controlled-release formulation remains in the body for hours rather than minutes.

"It's well known that alpha-lipoic acid helps protect mitochondria -- the 'power plant' found in each cell -- from being damaged by toxic byproducts created when those mitochondria are deluged with too much glucose or fatty acids," said Dr. Joseph L. Evans, MRI's vice president of Research and Development and Chief Scientific Officer. "We believe that there is a compelling scientific rationale that supports the use of alpha-lipoic acid to reduce oxidative stress (too many free radicals) in individuals with diabetes, a strategy that has been shown to offer symptomatic relief for diabetic peripheral neuropathy. MRI's approach has been to overcome the rapid elimination of alpha-lipoic acid by developing a controlled release formulation, which maintains an effective level in the body for a longer time."

"Alpha-lipoic acid has long been recognized for its beneficial impact on diabetic neuropathy," said Dr. Ira D. Goldfine, director, Division of Diabetes & Endocrine Research, Mount Zion Medical Center, University of California San Francisco. "However, the current oral formulations typically remain in the blood only a very short time, requiring either multiple daily doses or intravenous infusions. While more clinical studies are needed with controlled-release oral formulations of alpha-lipoic acid, it is clear that such preparations should be very helpful for diabetics suffering from complications such as neuropathy."

Glucotize(TM) has been evaluated in two previous clinical studies, and is currently being evaluated in three additional clinical studies at major university Diabetes Centers. For more information on these studies and on product availability, please visit www.glucotize.com.


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About the author:Mike Adams (aka the "Health Ranger") is a best selling author (#1 best selling science book on Amazon.com) and a globally recognized scientific researcher in clean foods. He serves as the founding editor of NaturalNews.com and the lab science director of an internationally accredited (ISO 17025) analytical laboratory known as CWC Labs. There, he was awarded a Certificate of Excellence for achieving extremely high accuracy in the analysis of toxic elements in unknown water samples using ICP-MS instrumentation. Adams is also highly proficient in running liquid chromatography, ion chromatography and mass spectrometry time-of-flight analytical instrumentation.

Adams is a person of color whose ancestors include Africans and Native American Indians. He's also of Native American heritage, which he credits as inspiring his "Health Ranger" passion for protecting life and nature against the destruction caused by chemicals, heavy metals and other forms of pollution.

Adams is the founder and publisher of the open source science journal Natural Science Journal, the author of numerous peer-reviewed science papers published by the journal, and the author of the world's first book that published ICP-MS heavy metals analysis results for foods, dietary supplements, pet food, spices and fast food. The book is entitled Food Forensics and is published by BenBella Books.

In his laboratory research, Adams has made numerous food safety breakthroughs such as revealing rice protein products imported from Asia to be contaminated with toxic heavy metals like lead, cadmium and tungsten. Adams was the first food science researcher to document high levels of tungsten in superfoods. He also discovered over 11 ppm lead in imported mangosteen powder, and led an industry-wide voluntary agreement to limit heavy metals in rice protein products.

In addition to his lab work, Adams is also the (non-paid) executive director of the non-profit Consumer Wellness Center (CWC), an organization that redirects 100% of its donations receipts to grant programs that teach children and women how to grow their own food or vastly improve their nutrition. Through the non-profit CWC, Adams also launched Nutrition Rescue, a program that donates essential vitamins to people in need. Click here to see some of the CWC success stories.

With a background in science and software technology, Adams is the original founder of the email newsletter technology company known as Arial Software. Using his technical experience combined with his love for natural health, Adams developed and deployed the content management system currently driving NaturalNews.com. He also engineered the high-level statistical algorithms that power SCIENCE.naturalnews.com, a massive research resource featuring over 10 million scientific studies.

Adams is well known for his incredibly popular consumer activism video blowing the lid on fake blueberries used throughout the food supply. He has also exposed "strange fibers" found in Chicken McNuggets, fake academic credentials of so-called health "gurus," dangerous "detox" products imported as battery acid and sold for oral consumption, fake acai berry scams, the California raw milk raids, the vaccine research fraud revealed by industry whistleblowers and many other topics.

Adams has also helped defend the rights of home gardeners and protect the medical freedom rights of parents. Adams is widely recognized to have made a remarkable global impact on issues like GMOs, vaccines, nutrition therapies, human consciousness.

In addition to his activism, Adams is an accomplished musician who has released over a dozen popular songs covering a variety of activism topics.

Click here to read a more detailed bio on Mike Adams, the Health Ranger, at HealthRanger.com.

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