Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Alcohol may enhance the sedative effects of Risperdal and should be avoided.1
• The oral solution should not be mixed with cola or tea.2
• Vitamin B6 & Vitamin E may help to reduce side effects associated with taking Risperdal.3
• Licorice Root (Glycyrrhiza radix) & White Peony Root (Paeoniae radix) may help prevent amenorrhea (lack of menstruation) that may be associated with Risperdal treatment.4
• Glycine may support the effectiveness of Risperdal, as individuals with schizophrenia found their symptoms lessened when glycine was added to their treatment of Risperdal.5
• Lithium using lithium with Risperdal has created side effects such as fever, confusion and delirium. Lithium may be present in medications or mineral supplements.6
• The sedative effects of these herbs may increase CNS side effects of risperdal: calamus, calendula, chamomile, California poppy, catnip, couch grass, elecampane, ginseng Siberian, goldenseal, gotu kola, hops, Jamaican dogwood, kava, lemon balm, sage, St. John's wort, sassafras, scullcap, shepherd's purse, stinging nettle, valerian, withania root, and yerba mansa.7
References1 Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999.
2 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
4 Yamada K, Kanba S, Yagi G, Asai M. Herbal medicine (shakuyaku-kanzo-to) in the treatment of risperidone-induced amenorrhea. J Clin Psychopharmacol 1999;19:380-1.
5 Heresco-Levy U, Ermilov M, Lichtenberg P, et al. High-dose glycine added to olanzapine and risperidone for the treatment of schizophrenia. Biol Psychiatry 2004;55:165-71.
6 Chen B, Cardasis W. Delirium induced by lithium and risperidone combination. Am J Psychiatry 1996;153:1233-4.
6 Swanson CL Jr., Price WA, McEvoy JP. Effects of concomitant risperidone and lithium treatment (letter). Am J Psychiatry 1995;152:1096.
7 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
7 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
7 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.