Researchers Speculate Alzheimer's is New Diabetes Type

Monday, March 09, 2009 by: Cathy Sherman
Tags: Alzheimer's, health news, Natural News

eTrust Pro Certified

Delicious Pin It
(NaturalNews) Some researchers and doctors are now saying Alzheimer's Disease (AD) is the new diabetes. Beware of any pharmaceutical claims and check the dietary hints at the end of this article first. Though there are similarities between the two disorders, it's too soon to jump to any drugs to prevent AD. Much more research is needed, so at this point, some clarification is definitely in order.

One of the prominent research studies being circulated is from Northwestern University, which found that insulin blocks the buildup of amyloid protein plaques. It is the buildup of such plaques in the brain that interferes with memory (one of the symptoms that defines AD) and has been found in autopsies, Before we get too excited about this research result, it needs to be pointed out that the plaques studied were on nerve cells of rats, not brain cells. Also, the type of insulin being used was not clearly defined.

A problem with this study is that the researchers also applied a drug, rosiglitazone, which was found to increase the effectiveness of the insulin. This drug is found in a widely advertised pharmaceutical many of us know as Avandia. Avandia is problematic, as it is not advised to be used by those taking insulin for diabetes control because of its involvement in heart attacks among such patients.

This is where the clarification in regard to insulin is important. Since 2005, studies at Brown University showed that insulin is produced not only in the pancreas, but also in the brain. In the Northwestern study, it was the rosiglitazone that bolstered the production of insulin in the brain and seemingly might offer a hope for those who are losing brain insulin due to aging or diabetes, with one caution. Though this finding demonstrates a significant potential to slow or deter AD pathogenesis, it is only for those who are not on insulin.

Types 1 and 2 diabetes result from a decrease in the production of insulin by the pancreas and are alike in that the amount of sugar in the blood increases. With the brain insulin-related condition now being called diabetes 3, blood sugar level is not affected. That seems to be a major difference.

There are also strong similarities. One is that deposits of the protein which cause the plaque have been found in the pancreas of those with diabetes 1 and 2, and in the brains of those with "diabetes 3", or AD. It is also recognized that diabetes 1 and 2 sufferers have up to a 65% higher risk of developing AD. These two circumstances indicate a strong link between diabetes and AD, but the causes of the relationship still need to be determined.

There are similar factors in the development of both disorders as well. In both we find impaired glucose/energy metabolism, oxidative stress, altered insulin-signaling pathways, some lipid metabolism dysfunction and inflammation. Some research has shown that vascular dysfunction contributes to AD, and it also is involved in diabetes.

Reactions from experts in the field have covered a wide range. As we've heard, some call the brain-centered insulin depletion "diabetes 3". Others say it is a totally different ailment which doesn't correspond to type 1 or type 2 diabetes, but appears to follow a different and more complex disease process which originates in the central nervous system.

A representative from the Alzheimer's Research Trust said that it's been believed for awhile that insulin and its growth factors play a very important role in Alzheimer's Disease. One suggestion is that the link could be in molecular changes which are affected by insulin. The trust is funding research into the way insulin acts on the brain in an attempt to increase understanding about Alzheimer's.

Professor Gregory Cole, from the University of California Los Angeles' Alzheimer's Disease Research Center, has been doing many interesting research studies in relation to AD, besides looking at the diabetes connection. He said: "This is a new finding. It is interesting that the brain makes very low levels of insulin. But its significance is unclear. The levels are so low that they have not been detected with less sensitive methods."

What may be more exciting to Natural News readers on the AD subject are Professor Cole's findings on other substances besides insulin which may block amyloid plaques. Curcumin, or turmeric, the yellow Indian spice used in curry, was also found to block the plaques in mice. In addition, he has found that docosahexenoic acid (DHA), an omega-3 fatty acid present in cold-water fish, substantially slowed AD's progression in mice inflicted with the disorder.

Does this mean that eating curried fish will help prevent Alzheimer's? It's definitely food for thought. Whether or not it can, it's at least good for a number of other ailments and certainly beats using a pharmaceutical with all of its harmful side effects! Just remember to choose the coldwater fish which are lowest in mercury, such as herring, freshwater trout, wild salmon, sardines, shad and anchovies.

It bears repeating that much more research needs to be done before there is unanimous agreement that Alzheimer's Disease is a type of diabetes. For most of us, this is not the crucial issue. What we do need to keep in mind and act on is the knowledge that a diet rich in raw foods and low in sugars, coupled with a lifestyle that includes plenty of daily exercise, will help to keep insulin at good levels.

If some people want to add some curried foods and coldwater fish to the mix, they just might find it true that fish is indeed brain food.


Journal of Alzheimers Disease http://www.j-alz.com/issues/16/vol16-4.html:
- Paula I. Moreira, Ana I. Duarte, Maria S. Santos, A. Cristina Rego, Catarina R. Oliveira,
"An Integrative View of the Role of Oxidative Stress, Mitochondria and Insulin in Alzheimer's Disease"
- V. Prakash Reddy, Xiongwei Zhu, George Perry, Mark A. Smith (Handling Editor: Ralph N. Martins) "Oxidative Stress in Diabetes and Alzheimer's Disease"
- Sajjad Muhammad, Angelika Bierhaus, Markus Schwaninger, "Reactive Oxygen Species in Diabetes-induced Vascular Damage, Stroke, and Alzheimer's Disease"
- Allan Jones, Philipp Kulozik, Anke Ostertag, Stephan Herzig, "Common Pathological Processes and Transcriptional Pathways in Alzheimer's Disease and Type 2 Diabetes"
- Elzbieta Kojro, Rolf Postina, "Regulated Proteolysis of RAGE and as Possible Link Between Type 2 Diabetes Mellitus and Alzheimer's Disease"


BBC News, 7 March 2005, "Study Suggests 'Type 3 Diabetes' "

Jenny Thompson, HSI e-newsletter, February 2009

About the author

Cathy Sherman is a freelance writer with a major interest in natural health and in encouraging others to take responsibility for their health. She can be reached through www.devardoc.com.

Get breaking news alerts on GMOs, fluoride, superfoods, natural cures and more...
Join over four million monthly readers. Email privacy 100% protected. Unsubscribe at any time.

Have comments on this article? Post them here:

comments powered by Disqus

Take Action: Support NaturalNews.com

Email this article to a friend

Permalink to this article:

Reprinting this article: Non-commercial use OK, cite NaturalNews.com with clickable link.

Embed article link: (copy HTML code below):
Most Popular
Today | Week | Month | Year

See all Top Headlines...


Now Available at ShopNaturalNews.com

O3 Essentials OraJuvenate™
A powerful, cleansing dental cream for maximum oral/dental health.
New Cancer Solutions
Over 3 hours of content covering today’s best cancer tests, how to kill cancer cells and the best diets and exercise routines.
Freeze-Dried 100% Organic Whole Corn
Our freeze-drying method preserves taste, texture and nutrients better than any other food preservation method ever invented.
Fenix TK35 Flashlight
Tough, waterproof, extremely bright and it’s touted to throw an 800+ lumen beam more than 1,000 feet into the night.
Inca Treasure Smoothie Pack
This pack of our four most popular superfoods from South America is the perfect combo pack for smoothie lovers.
Pink Himalayan Salt
This salt delivers significant levels of magnesium, zinc and selenium, with trace levels of dozens of other elements.
Pinhole Glasses - Aviator Style
Pinhole glasses are becoming famous for helping people improve their vision without the risks of laser surgery.
Oxy-Rich Facial Serum
O3 Essentials Jojoba Oxy-Rich Facial Serum is cellular nourishment for your skin. Helps smooth fine lines while enhancing tissue elasticity.
Freeze-Dried 100% Blackberry Halves
Our freeze-dried blackberry halves are grown in Serbia under strict organic standards.

Also on NaturalNews:

Health Ranger Videos
Activist music
CounterThink Cartoons
Food documentaries
FREE Special Reports
Colloidal Silver

Advertise with NaturalNews...

Support NaturalNews Sponsors:

Advertise with NaturalNews...

Most Popular Stories

Flu shot kills 19-year-old, but vaccine industry still has total immunity against lawsuits
Here's a nutty fact: Eating more tree nuts lowers the risk of all-cause death by up to 20 percent
Six important facts you're not being told about lost Malaysia Airlines Flight 370
Malaysia Airlines Flight 370 now clearly a government cover-up: All evidence contradicts official story
10 other companies that use the same Subway yoga mat chemical in their buns
BLM fracking racket exposed! Armed siege and cattle theft from Bundy ranch really about fracking leases
High-dose vitamin C injections shown to annihilate cancer
U.S. treating meat with ammonia, bleach and antibiotics to kill the '24-hour sickness'
USDA to allow U.S. to be overrun with contaminated chicken from China
Vaccine fraud exposed: Measles and mumps making a huge comeback because vaccines are designed to fail, say Merck virologists
Battle for humanity nearly lost: global food supply deliberately engineered to end life, not nourish it
Diet soda, aspartame linked to premature deaths in women

25 Amazing Facts About Food

This FREE downloadable report unveils a collection of astonishing and little-known facts about the food we eat very day. Click here to read it now...


Resveratrol and its Effects on Human Health and Longevity - Myth or Miracle.

Unlock the secrets of cellular health with the "miracle" nutrient Resveratrol Click here to read it now...


Nutrition Can Save America

FREE online report shows how we can save America through a nutrition health care revolution. "Eating healthy is patriotic!" Click here to read it now...

The Healing Power of Sunlight and Vitamin D

In this exclusive interview, Dr. Michael Holick reveals fascinating facts on how vitamin D is created and used in the human body to ward off chronic diseases like cancer, osteoporosis, mental disorders and more. Click here to read it now...

Vaccines: Get the Full Story

The International Medical Council on Vaccination has released, exclusively through NaturalNews.com, a groundbreaking document containing the signatures of physicians, brain surgeons and professors, all of which have signed on to a document stating that vaccines pose a significant risk of harm to the health of children. Click here to read it now...

Health Ranger Storable Organics

GMO-free, chemical-free foods and superfoods for long-term storage and preparedness. See selection at www.StorableOrganics.com

Recommended Resources On:

Natural News trends
Health Ranger news
Natural News GMOs
Mike Adams tracker
Natural News photos
Natural News Global
Natural News in focus
Natural News connect
Natural News shocking stories
Natural News radar
Health freedom
Dr. Paul Offit

This site is part of the Natural News Network © 2014 All Rights Reserved. Privacy | Terms All content posted on this site is commentary or opinion and is protected under Free Speech. Truth Publishing International, LTD. is not responsible for content written by contributing authors. The information on this site is provided for educational and entertainment purposes only. It is not intended as a substitute for professional advice of any kind. Truth Publishing assumes no responsibility for the use or misuse of this material. Your use of this website indicates your agreement to these terms and those published here. All trademarks, registered trademarks and servicemarks mentioned on this site are the property of their respective owners.

eTrust Pro Certified Android app on Google Play

Sign up for the FREE Natural News Email Newsletter

Receive breaking news on GMOs, vaccines, fluoride, radiation protection, natural cures, food safety alerts and interviews with the world's top experts on natural health and more.

Join over 7 million monthly readers of NaturalNews.com, the internet's No. 1 natural health news site. (Source: Alexa.com)

Your email address *

Please enter the code you see above*

No Thanks

Already have it and love it!

Natural News supports and helps fund these organizations:

* Required. Once you click submit, we will send you an email asking you to confirm your free registration. Your privacy is assured and your information is kept confidential. You may unsubscribe at anytime.