Chinese skullcap shown to improve lung injuries caused by myocardial ischemia
04/09/2019 // Ralph Flores // Views

Researchers from the National Yang-Ming University School of Medicine in Taiwan found that baicalein, a compound present in Chinese skullcap (Scutellaria baicalensis), can inhibit production of tumor necrosis factor-alpha (TNF-a) and regulate pro- and anti-apoptotic signaling elements. The study was published in The American Journal of Chinese Medicine.

  • Chinese skullcap is used in traditional medicine to treat cardiovascular disease.
  • Researchers looked at the efficacy of baicalein against lung injury brought about by myocardial ischemia and reperfusion (I/R). To induce myocardial I/R, a 40-minute occlusion on the left anterior descending coronary artery was made. This increased histological damage, as well as the wet-to-dry weight ratio of lungs.
  • In addition, it also significantly increased terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL)-positive nuclei and caspase-3 activation, including serum and bronchoalveolar lavage fluid levels of TNF-a, interleukin-1-beta (IL-1B), and interleukin-6 (IL-6).
  • In the study, the researchers injected mice with 3, 10, and 30 mg of baicalein per kilogram of body weight for 10 minutes before inducing myocardial I/R.
  • Mice treated with baicalein exhibited reduced histological damage, wet-to-dry-weight ratio, and lung apoptosis.
  • Baicalein also inhibited TNF-a, IL-1B, and IL-6 levels from increasing.
  • It also improved Bcl-2 and decreased p53, Bax, and cytochrome c levels in the lungs.

The researchers concluded that baicalein can help with the symptoms of lung injury after being induced with myocardial I/R.

Learn about the other benefits of Chinese skullcap at

Journal Reference:

Lai CC, Huang PH, Yang AH, Chiang SC, Tang CY, Tseng KW, Huang C-H. BAICALEIN ATTENUATES LUNG INJURY INDUCED BY MYOCARDIAL ISCHEMIA AND REPERFUSION. The American Journal of Chinese Medicine. 2017;45(04):791–811. DOI: 10.1142/S0192415X17500422

Take Action:
Support Natural News by linking to this article from your website.
Permalink to this article:
Embed article link:
Reprinting this article:
Non-commercial use is permitted with credit to (including a clickable link).
Please contact us for more information.
Free Email Alerts
Get independent news alerts on natural cures, food lab tests, cannabis medicine, science, robotics, drones, privacy and more.
App Store
Android App
eTrust Pro Certified

This site is part of the Natural News Network © 2022 All Rights Reserved. Privacy | Terms All content posted on this site is commentary or opinion and is protected under Free Speech. Truth Publishing International, LTD. is not responsible for content written by contributing authors. The information on this site is provided for educational and entertainment purposes only. It is not intended as a substitute for professional advice of any kind. Truth Publishing assumes no responsibility for the use or misuse of this material. Your use of this website indicates your agreement to these terms and those published here. All trademarks, registered trademarks and servicemarks mentioned on this site are the property of their respective owners.

This site uses cookies
Natural News uses cookies to improve your experience on our site. By using this site, you agree to our privacy policy.
Learn More
Get 100% real, uncensored news delivered straight to your inbox
You can unsubscribe at any time. Your email privacy is completely protected.