Home
Newsletter
Events
Blogs
Reports
Graphics
RSS
About Us
Support
Write for Us
Media Info
Advertising Info
Osteoporosis drugs

Osteoporosis Drugs Linked to Rotting Jaw Disease

Wednesday, March 04, 2009 by: David Gutierrez, staff writer
Tags: osteoporosis drugs, health news, Natural News


Most Viewed Articles
https://www.naturalnews.com/025766_osteoporosis_drugs_bone.html
Delicious
diaspora
Print
Email
Share

(NaturalNews) Widely used osteoporosis drugs can significantly increase the risk of bone death in the jaw, according to a study conducted by researchers from the University of Southern California (USC) School of Dentistry and published in the Journal of the American Dental Association.

Researchers found an increased prevalence of osteonecrosis of the jaw (ONJ) among the 208 patients in the School of Dentistry's medical records database who were taking the osteoporosis drug alendronate (marketed as Fosamax).

ONJ occurs when reduced blood flow to the bones in the jaw leads to the death of bone tissue, producing symptoms including infection, loose teeth, exposed bone, soft-tissue swelling and pain. Up until the publication of the current results, researchers had believed that the ONJ risk from oral osteoporosis drugs was "negligible."

Fosamax is the 21st most common drug prescribed in the United States, and the most widely prescribed oral drug in the bisphosphonate family.

Bisphosphonates protect against fractures and the loss of bone mass in osteoporosis patients by interfering with the process by which the body removes calcium and other minerals from bones. Well-known side effects of the drugs include an elevated risk of thigh-bone fractures, inflammatory eye disease and irregular heartbeat. Prior research has shown that patients taking high intravenous doses of bisphosphonates also have an elevated risk of ONJ.

According to the current study, however, ONJ risk is increased even in those who take lower doses of oral bisphosphonates for as little as one year. The researchers found that ONJ tends to occur after a routine tooth extraction, perhaps because bisphosphonates have lowered the bones' resistance to bacterial infection.

Researcher and dentist Parish Sedghizadeh was inspired to conduct the study when he noticed unusually high ONJ rates among patients at his dental clinic in recent years -- as many as four per week. The USC School of Dentistry has now adopted a policy of screening patients for bisphosphonate use before performing dental procedures.

Sources for this story include: www.washingtonpost.com.

Receive Our Free Email Newsletter

Get independent news alerts on natural cures, food lab tests, cannabis medicine, science, robotics, drones, privacy and more.


comments powered by Disqus


Natural News Wire (Sponsored Content)

Science.News
Science News & Studies
Medicine.News
Medicine News and Information
Food.News
Food News & Studies
Health.News
Health News & Studies
Herbs.News
Herbs News & Information
Pollution.News
Pollution News & Studies
Cancer.News
Cancer News & Studies
Climate.News
Climate News & Studies
Survival.News
Survival News & Information
Gear.News
Gear News & Information
Glitch.News
News covering technology, stocks, hackers, and more