Subscribe (free)
About NaturalNews
Contact Us
Write for NaturalNews
Media Info
Advertising Info

FDA Decides Against Warnings on Epilepsy Medication Suicide Risk

Saturday, January 03, 2009 by: David Gutierrez, staff writer
Tags: epilepsy, health news, Natural News

Most Viewed Articles

(NaturalNews) The FDA has decided against placing new warning labels on anti-seizure medications used to treat epilepsy, in spite of recent findings that those drugs can increase a patient's risk of suicide.

In January, the FDA raised the possibility of labeling 11 anti-seizure drugs with "black box" warnings, after numerous studies linked them to increased risks of suicidal behavior: carbamazepine (marketed as Carbatrol, Equetro, Tegretol and Tegretol XR), felbamate (marketed as Felbatol), gabapentin (marketed as Neurontin), lamotrigine (marketed as Lamictal), levetiracetam (marketed as Keppra), oxcarbazepine (marketed as Trileptal), pregabalin (marketed as Lyrica), tiagabine (marketed as Gabitril), topiramate (marketed as Topamax), valproate (marketed as Depakote, Depakote ER, Depakene and Depacon) and zonisamide (marketed as Zonegran).

The so-called anti-convulsants are used primarily to treat epilepsy, bipolar disorder and migraines.

In early July, the FDA announced its intention to add a black box warning about suicide risk to the drugs' labels. This is the strongest warning that the FDA can place on a product without withdrawing from the market.

The next week, however, an FDA advisory panel recommended against adding a black box warning. While the panel had found, upon review of study data, that there was definitely an association between anti-convulsant use and increased suicide risk, it was concerned that a black box warning might lead to reduced use of the drugs.

"If we have good drugs that are working, we have to be very careful about scaring patients into not taking them," said FDA adviser Rochelle Caplan, of the University of California-Los Angeles.

Following the panel's recommendation, the FDA reversed its position and announced that it would no longer add a black box warning the drugs. The agency's prior advice to doctors still stands, however: to be alert for any changes in the "mood, behavior and actions" of those taking anti-convulsant drugs.

Sources for this story include: www.efluxmedia.com; www.businessweek.com.

Receive Our Free Email Newsletter

Get independent news alerts on natural cures, food lab tests, cannabis medicine, science, robotics, drones, privacy and more.

comments powered by Disqus

Natural News Wire (Sponsored Content)

Science News & Studies
Medicine News and Information
Food News & Studies
Health News & Studies
Herbs News & Information
Pollution News & Studies
Cancer News & Studies
Climate News & Studies
Survival News & Information
Gear News & Information
News covering technology, stocks, hackers, and more