According to a report, Australia had previously agreed to purchase 51 million doses of the Wuhan coronavirus (COVID-19) vaccine being developed by CSL, an Australian multinational specialty biotechnology company, and the University of Queensland (UQ).
A positive candidate for a COVID-19 vaccine developed by CSL and UQ was abandoned in 2020 after trial participants returned false HIV-positive results. The Australian government immediately scrapped its deal with CSL and UQ and said that orders of other vaccines would be used to fill the previous order. At the time, the Australian government said it entered an agreement for the Novavax vaccine and increased its existing order of the Oxford-AstraZeneca vaccine.
CSL and UQ claimed that the positive results were false, adding that the trial volunteers' health was not at risk.
The vaccine was in stage one of trials, and it was allegedly effective in making antibodies. However, the COVID-19 vaccine also generated HIV antibodies in some recipients, meaning it showed false positives for HIV.
Further testing proved that HIV wasn't there. CSL and UQ said fixing the flaw would take at least one year, resulting in the decision to abandon the trial.
Brendan Murphy, at the time the secretary of the Australian Department of Health and Aged Care, said while the vaccine was likely to work, the government knew that they "didn't want to have any issues with confidence, and this false-positive test may have caused some confusion and lack of confidence."
Paul Young, the COVID-19 vaccine co-lead, said the decision was "devastating" because the research team had already spent 11 months working on the project. "While this is a tough decision to take, the urgent need for a vaccine has to be everyone's priority," added Young.
Other medical experts claimed the "realistic" decision to abandon the CSL-UQ vaccine was necessary, especially because it reflects the reality of vaccine development. (Related: Worldwide Vaccine Holocaust CONFIRMED as wave of studies reveal devastating rise in All-Cause Mortality (ACM).)
Sanjaya Senanayake, an infectious diseases expert from the Australian National University, explained that generally, at least 90 percent of vaccines never make it to market. "As a global community, we have been spoilt with the unprecedented swiftness and success with which the development of COVID-19 vaccines has taken place," said Senanayake.
A study published in August 2023 revealed that cases of HIV false positive testing were coming in for both patients who had SARS-CoV-2 infection and some who received COVID-19 vaccines.
Researchers who conducted the study searched their data system among 39,110 records and results found 87 false positive HIV results distributed among patients who had COVID-19, vaccination, and presumably both.
However, the study mostly focused on the link between false positives and COVID-19 infection.
According to another study from 2023, there was a "temporal relationship between COVID-19 test positivity and the false positive HIV result from multiple studies."
An earlier study from 2023 found that there were more cases of false positive HIV enzyme-linked immunosorbent assay (ELISA) tests without PCR confirmation and that the virus was actually present.
The researchers said that based on the literature, the spike proteins of SARS-CoV-2 have structural similarities to some viruses, which makes anti-body cross-reactivity between the two viruses feasible.
They added that a spike protein present on the outer surface of SARS-CoV-2 can cross-react with antibodies from other closely related coronaviruses, which suggests that immunoassay tests are adversely affected, in turn leading to false-positive results.
They concluded that seasonal enteroviruses, "such as HCoV-OC43 and HCoV-HKU1, cross-react strongly with SARS-CoV-2."
These studies prompt several questions that need answers:
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