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Oat extract can protect against alcohol-induced liver damage

03/13/2019 // Michelle Simmons // Views

Tags: Alcohol, alternative medicine, Avena sativa, food is medicine, goodfood, goodhealth, goodmedicine, liver damage, liver disease, natural cures, natural medicine, oat extract, oats, prevention, prophylactic, superfoods

Researchers from India have found that eating oats (Avena sativa) can help prevent alcohol-induced liver damage. In their study, which was published in the journal Nutrition Research, the research team looked at the protective effect of oat extract against alcohol-induced acute liver injury in a mouse model.

• Research has found an association between consumption of oats and lower risk of cardiovascular disease, diabetes, and gastrointestinal disorders.
• However, the effect of oat extract in the prevention of acute liver injury is not fully understood.
• For their study, the research team hypothesized that oat extract would exert a protective effect against acute liver injury brought about by alcohol intake in a mouse model.
• In conducting the study, the research team pretreated mice with phenolic-enriched ethyl acetate fraction of oats at doses of 125 and 250 milligrams per kilogram (mg/kg) a day for 12 consecutive days.
• Then, they induced acute liver injury by administering five doses of 50 percent ethanol or 10 grams per kilogram (g/kg) body weight to mice every 12 hours.
• After that, the team measured the alcohol-induced liver injury through different parameters.
• The results showed that pretreatment with the oat extract at 250 mg/kg significantly reduced the levels of liver injury markers and significantly increased the levels of antioxidant defenses.
• In addition, it inhibited inflammatory pathways.

From these findings, the research team concludes that oats can be used as a dietary intervention to protect against alcohol-induced liver damage.

To read more studies on foods that help protect against liver damage, visit LiverDamage.news.

Journal Reference:

Mir SM, Sahu BD, Koneru M, Kuncha M, Jerald MK, Ravuri HG, Kanjilal S, Sistla R. SUPPLEMENTATION OF OAT (AVENA SATIVA L.) EXTRACT ABATES ALCOHOL-INDUCED ACUTE LIVER INJURY IN A MOUSE MODEL. Nutrition Research. June 2018; 54: 80-92. DOI: 10.1016/j.nutres.2018.04.002

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