antioxidant

Antioxidant MitoQ rejuvenates aging arteries


Most Viewed Articles
Popular on Facebook
The five biggest lies about Ebola being pushed by government and mass media
Why does the CDC own a patent on Ebola 'invention?'
White House admits staging fake vaccination operation to gather DNA from the public
Ultraviolet light robot kills Ebola in two minutes; why doesn't every hospital have one of these?
EXCLUSIVE: Natural News tests flu vaccine for heavy metals, finds 25,000 times higher mercury level than EPA limit for water
Truvia sweetener a powerful pesticide; scientists shocked as fruit flies die in less than a week from eating GMO-derived erythritol
Irrefutable proof we are all being sprayed with poison: 571 tons of toxic lead 'chemtrailed' into America's skies every year
Russia taking McDonald's to court, threatens countrywide shutdown
Oregon man serving prison sentence for collecting rainwater on his own property
The best way to help your body protect itself against Ebola (or any virus or bacteria)
Senator who attacked Doctor Oz over dietary supplements received over $146,000 in campaign contributions from Big Pharma mega-retailer and Monsanto
Global warming data FAKED by government to fit climate change fictions
Healthy 12-year-old girl dies shortly after receiving HPV vaccine
Ebola outbreak may already be uncontrollable; Monsanto invests in Ebola treatment drug company as pandemic spreads
HOAX confirmed: Michelle Obama 'GMOs for children' campaign a parody of modern agricultural politics
Ben & Jerry's switches to non-GMO, Fair Trade ice cream ingredients
W.H.O. contradicts CDC, admits Ebola can spread via coughing, sneezing and by touching contaminated surfaces
BREAKING: CDC whistleblower confesses to MMR vaccine research fraud in historic public statement

Delicious
(NaturalNews) An antioxidant specifically engineered to seek out the mitochondria within cells may help reverse the aging of arteries, according to a study conducted by researchers from the University of Colorado-Boulder and published in The Journal of Physiology.

The study was funded by a grant from the National Institute on Aging.

Blood vessels aged by free radicals

To keep the body healthy, blood vessels must be able to dilate and contract as needed. When dilation is required, the endothelium (a thin layer of cells lining the blood vessels) produces a chemical known as nitric oxide. Nitric oxide is highly vulnerable to destruction by free radicals, however -- particularly the free radical superoxide, which is actually produced by the body's own mitochondria. Superoxide also degrades one of the enzymes that functions as a precursor to nitric oxide, leading to even lower levels of the chemical and decreased dilation of blood vessels. This, in turn, increases the risk of heart disease.

Superoxide is necessary to maintain cellular function, but as the body ages, mitochondria begin to produce it in higher quantities. At the same time, levels of antioxidants in the body often decrease with age, which leads to even greater circulating levels of superoxide. Superoxide then begins to cause damage to the mitochondria themselves -- which induces the mitochondria to produce even more superoxide, leading to even lower blood levels of antioxidants and more cellular damage.

"You have this kind of balance, but with aging there is this shift," lead author Rachel Gioscia-Ryan said. "There become way more reactive oxygen species than your antioxidant defenses can handle."

Finding an antioxidant that works

Previous studies have attempted to use antioxidant supplements to lower superoxide levels and thereby improve vascular dilation, but none have been successful. The researchers in the current study hypothesized that most antioxidants do not reach mitochondria and therefore have a limited impact on superoxide.

In order to get around this problem, the researchers specifically engineered an antioxidant for affinity for mitochondria. This chemical, MitoQ, was formed by adding a mitochondria-binding molecule to coenzyme Q10 (also known as ubiquinone or CoQ10).

"The question is, 'Why aren't we all just taking a bunch of vitamin C?" Gioscia-Ryan said. "Scientists think that, taken orally, antioxidants like vitamin C aren't getting to the places where the reactive oxygen species are being made. MitoQ basically tracks right to the mitochondria."

When the researchers gave elderly mice a MitoQ supplement for four weeks, their arteries went from functioning at a level equivalent to a 70-to-80-year-old human to a level equivalent to a 25-to-35-year-old human. In addition, the mice's levels of nitric oxide increased, their levels of oxidative stress decreased and their mitochondrial health improved.

"One of the hallmarks of primary aging is endothelial dysfunction," Gioscia-Ryan said. "MitoQ completely restored endothelial function in the old mice. They looked like young mice."

Although tests into its function are still in preliminary stages, MitoQ can already be purchased as a dietary supplement and skin cream. CoQ10, the chemical used as the base for MitoQ, can also be purchased as a nutritional supplement.

CoQ10 is a substance naturally produced by the body to help enzymes carry out various functions -- including helping mitochondria produce adenosine triphosphate (ATP), the major cellular energy source. CoQ10 has also been linked, on its own, to prevention of cellular damage and improvements in high blood pressure. It is also being investigated for a number of other potential benefits, including fighting cancer, improving cognitive health, slowing the effects of aging, reducing diabetic neuropathy pain, lowering high cholesterol and improving heart health.

Sources for this article include:

http://www.colorado.edu

http://www.naturalnews.com

http://science.naturalnews.com

Join over four million monthly readers. Your privacy is protected. Unsubscribe at any time.
comments powered by Disqus
Take Action: Support NaturalNews.com by linking back to this article from your website

Permalink to this article:

Embed article link: (copy HTML code below):

Reprinting this article:
Non-commercial use OK, cite NaturalNews.com with clickable link.

Follow Natural News on Facebook, Twitter, Google Plus, and Pinterest

Advertise with NaturalNews...

Support NaturalNews Sponsors:

Advertise with NaturalNews...

GET SHOW DETAILS
+ a FREE GIFT

Sign up for the FREE Natural News Email Newsletter

Receive breaking news on GMOs, vaccines, fluoride, radiation protection, natural cures, food safety alerts and interviews with the world's top experts on natural health and more.

Join over 7 million monthly readers of NaturalNews.com, the internet's No. 1 natural health news site. (Source: Alexa.com)

Your email address *

Please enter the code you see above*

No Thanks

Already have it and love it!

Natural News supports and helps fund these organizations:

* Required. Once you click submit, we will send you an email asking you to confirm your free registration. Your privacy is assured and your information is kept confidential. You may unsubscribe at anytime.