cancer

Breast cancer drugs may stop cancer, but they also cut life short due to toxicity

Tuesday, August 23, 2011 by: S. L. Baker, features writer
Tags: breast cancer, toxic, health news

eTrust Pro Certified

Most Viewed Articles
Popular on Facebook
BACK INTO THE CLOSET: Why U.S. reporters are not allowed to write about rainbow events in nations where being gay is still condemned
Depopulation test run? 75% of children who received vaccines in Mexican town now dead or hospitalized
INVESTIGATION: Three days before Dr. Bradstreet was found dead in a river, U.S. govt. agents raided his research facility to seize a breakthrough cancer treatment called GcMAF
A family destroyed: Six-month-old dies after clinic injects baby with 13 vaccines at once without mother's informed consent
Biologist explains how marijuana causes tumor cells to commit suicide
BOMBSHELL: China and America already at war: Tianjin explosion carried out by Pentagon space weapon in retaliation for Yuan currency devaluation... Military helicopters now patrolling Beijing
Companies begin planting microchips under employees' skin
BAM! Chipotle goes 100% non-GMO; flatly rejecting the biotech industry and its toxic food ingredients
ECONOMIC SLAVERY FOR ALL: While we were distracted with the Confederate flag flap, Congress quietly forfeited our entire economic future via fast-track trade authority
McDonald's in global profit free fall as people everywhere increasingly reject chemically-altered toxic fast food
March Against Monsanto explodes globally... World citizens stage massive protests across 38 countries, 428 cities... mainstream media pretends it never happened
SCOTUS same-sex marriage decision may have just legalized the concealed carry of loaded firearms across all 50 states, nullifying gun laws everywhere
Vicious attack on Dr. Oz actually waged by biotech mafia; plot to destroy Oz launched after episode on glyphosate toxicity went viral
Nearly every mass shooting in the last 20 years shares one surprising thing? and it's not guns
Holistic cancer treatment pioneer Dr. Nicholas Gonzalez dies suddenly; patients mourn the loss of a compassionate, innovative doctor who helped thousands heal from cancer
Inuit Elders tell NASA Earth Axis Shifted
Wild eyes and bowl cuts: Why do mass shooters always share the same hair styles and crazed zombie stares?
Genetically white woman now claims self-identify as black: If you can choose your gender, can you also choose your race? What about your species? Can a human claim to be a llama?
Delicious
(NaturalNews) Here's another case of a so-called "wonder drug" heavily promoted by Big Pharma having a darker side than anyone knew. It turns out aromatase inhibitors (sold under the names Femara, Aromasin, and Arimidex), widely prescribed to huge numbers of women who've been diagnosed with estrogen receptor-positive breast cancer, could be so toxic in the body they do nothing to prolong life -- and might even shorten it.

Based on the findings of several studies, most doctors now recommend one of the aromatase inhibitor (AIs) after women with estrogen-positive breast cancer have initial treatment with surgery and often chemotherapy and radiation therapy. An AI medication has been considered a better choice than the other anti-estrogen treatment, tamoxifen, because AIs have been thought to have more benefits and fewer serious side effects.

However, research just published in the Journal of the National Cancer Institute concludes that the toxic impact of aromatase inhibitors apparently explains why breast cancer patients taking AIs don't live any longer than women taking tamoxifen. Bottom line: the study suggests that even if AIs slow down or halt the growth of estrogen driven breast cancer, women may lose their lives not to a malignancy -- but to the negative impact the drugs have on their bodies.

AIs block the enzyme aromatase, which turns the hormone androgen into small amounts of estrogen in the body. So they reduce the amount of estrogen available that can stimulate the growth of estrogen-driven breast cancer cells. This class of drugs doesn't halt ovaries from making estrogen, so AIs are only used in post-menopausal women. The medications are normally prescribed as an alternative to tamoxifen or after earlier treatment with tamoxifen (which often has intolerable side effects).

Overall, AI therapy alone is associated with a reduction in breast cancer recurrence -- but doesn't result in women living any longer. What's more, the drugs have been found to produce a host of concerning adverse toxic effects on the body. And it's this toxicity that may explain the lack of overall survival benefit in postmenopausal breast cancer patients, according to researchers Eitan Amir, of the Division of Medical Oncology and Hematology at Princess Margaret Hospital in Toronto, Ontario, and colleagues.

The research team conducted a systematic review of all randomized trials which compared AIs and tamoxifen in postmenopausal women. Using results from seven trials involving 30,023 breast cancer patients, the scientists performed a meta-analysis of the data. The results showed that, compared to tamoxifen, longer use of AIs was associated with more heart disease and bone fractures. However, tamoxifen users had higher rates of blood clots and cancer of the womb. There were no differences in the risk of stroke or other types of cancer. Overall there was no survival benefit to AIs, even though the drugs seem to have a positive effect on breast cancer recurrence.

The researchers concluded that the toxicity of AIs was most likely behind the drugs failure to prolong life. Using tamoxifen first and then switching to AIs for 2 to 3 years was associated with a lower risk of death unrelated to breast cancer compared to the use of either AIs or tamoxifen alone. The scientists speculate that this is because switching between the two drugs lowers the toxicity of AIs in the body.

In an accompanying editorial, Nancy E. Davidson, M.D., Shannon Puhalla, M.D., and Rachel C. Jankowitz, M.D., of the UPMC Cancer Center at Magee-Womens Hospital, concluded that doctors should "..choose initial endocrine therapy for the individual patient with careful attention to the risk of breast cancer recurrence, the risk of toxicity, and comorbidities."

As NaturalNews has reported extensively, a host of research is pointing to far safer and even non-toxic natural therapies than mainstream medicine's current standard breast cancer treatment strategies. For example, there is evidence parsley and other plants may contain phytochemicals that help stop breast cancer (http://www.naturalnews.com/032410_parsley_tu...). Vitamin D (http://www.naturalnews.com/032222_breast_can...) appears to hold great promise in the fight against breast malignancies, too.

For more information:
http://jnci.oxfordjournals.org/
http://www.naturalnews.com/breast_cancer.htm...

Follow real-time breaking news headlines on
Breast cancer at FETCH.news
Join over four million monthly readers. Your privacy is protected. Unsubscribe at any time.
comments powered by Disqus
Take Action: Support NaturalNews.com by linking back to this article from your website

Permalink to this article:

Embed article link: (copy HTML code below):

Reprinting this article:
Non-commercial use OK, cite NaturalNews.com with clickable link.

Follow Natural News on Facebook, Twitter, Google Plus, and Pinterest

Colloidal Silver

Advertise with NaturalNews...

Support NaturalNews Sponsors:

Advertise with NaturalNews...

GET SHOW DETAILS
+ a FREE GIFT

Sign up for the FREE Natural News Email Newsletter

Receive breaking news on GMOs, vaccines, fluoride, radiation protection, natural cures, food safety alerts and interviews with the world's top experts on natural health and more.

Join over 7 million monthly readers of NaturalNews.com, the internet's No. 1 natural health news site. (Source: Alexa.com)

Your email address *

Please enter the code you see above*

No Thanks

Already have it and love it!

Natural News supports and helps fund these organizations:

* Required. Once you click submit, we will send you an email asking you to confirm your free registration. Your privacy is assured and your information is kept confidential. You may unsubscribe at anytime.