The Hidden Dangers of Roundup

Thursday, February 05, 2009 by: Dr. Gregory Damato, Ph.D.
Tags: Roundup, health news, Natural News

eTrust Pro Certified

Delicious Pin It
(NaturalNews) Roundup is the world`s most popular herbicide used to control weeds all over the planet and is omnipresent in the food chain of animals and humans. Roundup is claimed to have an active ingredient known as glyphosate (G) and said to be safe for humans even though plants are readily killed. In a first of its kind published study, French researchers recently sought to examine the toxicity of four popular G-based herbicide formulations on human placental cells, kidney cells, embryonic cells and neonate umbilical cord cells and surprisingly found total cell death of each of these cells within 24 hours.

As the percentage of genetically modified (GM) soy in the US burgeons to over 91 percent [1], researchers are beginning to publish harbingers for the potential of a maelstrom of future health problems from GMOs (genetically modified organisms) [2, 3]. One of the potential harmful triggers includes the increased amounts of chemicals present in the environment disseminating at an alarming rate with few researchers examining the combined effects of these xenobiotics on plants, animals or humans. Similarly, much of the existing research on GMOs has been undertaken on the individual organism itself and neglects to examine the more important ecological issue of synergism. This point is very notable because the world`s most popular herbicide known as Monsanto`s Roundup contains a blend of glyphosate (G) and several unknown adjuvants. The exact ingredients in Roundup are not disclosed to the general public and are kept confidential as they are labeled, "trade secrets". Monsanto assures the public these ingredients are inert and are therefore non-toxic. The most predominant adjuvant in Roundup seems to be polyethoxylated tallowamine or POEA [4, 5], which has been implicated in ocular burns, redness, swelling, blisters, nausea and diarhhea [6]. POEA is one of the most prevalent pollutants found in rivers all over the world. Problems begin to arise when G alone interacts with POEA and other unknown ingredients activating and accelerating the resultant mixture known as Roundup [7].

Monsanto patented its G propriety blend and named it Roundup in the 1970`s to kill broadleaf and cereal leave weeds. G is the active ingredient utilized in nearly 75% of all edible GM plants that have been engineered to tolerate high levels of this form of G [8]. G works by inhibiting an enzyme that synthesizes the amino acids tyrosine, tryptophan and phenylalanine thereby killing the weed. Researchers examining the amounts of herbicide used on GMO soy have concluded that the GMO soy typically receives several more pounds of G than conventionally grown soy per acre [9]. Furthermore, researchers have found that several types of newly created superweeds resistant to Roundup (e.g., pigweed, ryegrass and marestail) have been rapidly surfacing leading to increased amounts of Roundup on such crops [10]. These farmers have been told to use increasingly potent mixtures of herbicides and not Roundup alone [11]. In fact, there has been a more than 1900% increase in G use on Roundup Ready soybeans from 1994 to 2006 [12].

For the first time, French researchers recently sought to examine the toxicity of four G-based herbicide formulations on human placental cells, kidney cells, embryonic cells and neonate umbilical cord cells [13]. The researchers used the four most common types of Roundup utilized worldwide: Roundup Express, Roundup Bioforce, Roundup Grand Travaux and Roundup Grand Travaux Plus at lower concentration levels than would be normally found in plants and in animal feed. The researchers sought to determine the levels of necrosis (death of cells due to injury, disease or loss of blood supply) and apotosis (programmed cell death) of each of these cells based on exposure to various dilutions of each of the four Roundup products as well as G, POEA and AMPA (the main metabolite of G at 14 different concentrations of 10 ppm to 2%).

The researchers were surprised by the findings and reported that all four herbicides caused cellular death for all four types of cells within 24 hours. The researchers reported several mechanisms by which the herbicides caused the cells to die including: cell membrane rupture and damage, mitochondrial damage and cell asphyxia. Following these findings, the researchers tested G, AMPA and POEA by themselves and concluded that, "It is very clear that if G, POEA, or AMPA has a small toxic effect on embryonic cells alone at low levels, the combination of two of them at the same final concentration is significantly deleterious".

Although Monsanto claims that G metabolizes into a harmless and inert substance known as AMPA, the researchers found that AMPA was more toxic to human cells than G. This finding is very noteworthy considering AMPA is more stable and present in soil, plants, food and wastewater (2 to 35 ppm) compared with G (.1 to 3 ppm) [14]. AMPA was also found to synergistically increase the toxicity of G and POEA.

The researchers also reported that G acted very quickly at concentrations 500 to 1000 times lower than present agricultural levels to induce programmed cell death. G alone was found to induce mitochondrial toxicity without cell membrane damage. Furthermore, the researchers tested very weak concentrations (.005%) of Roundup and reported cell death, lack of adhesion, shrinking and fragmentation in the cells undergoing apoptosis. The embryonic cells were the most sensitive indicating another major reason to eat only organic foods while pregnant.

Although previous researchers have proposed that the supposed "inert ingredients" alter the role of cell membrane disruptors in fish, amphibians, microorganisms [15] and plants [16], independent of G, this study is the first of its kind to report similar findings in human cells and immediately calls for strict monitoring of the agricultural usage of Roundup. The researchers concluded that, "the proprietary mixtures available on the market could cause cell damage and even death around residual levels to be expected, especially in food and feed derived from R [Roundup] formulation-treated crops".


1.GMO Compass. USA: Cultivations of GM plants in 2007. 2008 [cited January 15, 2009]; Available from:
2.Finamore, A., et al., Intestinal and peripheral immune response to MON810 maize ingestion in weaning and old mice. Journal of Agriculture and Food Chemistry, 2008. 56: p. 11533-11539.
3.Velimirov, A., et al., Biological effects of transgenic maize NK603xMON810 fed in long term reproduction studies in mice. Unpublished study: Institute fur Ernahrung, Austria., November 11, 2008.
4.Acquavella, J.F., et al., Human occular effects frim self-reported exposures to Roundup herbicides. Human & Experimental Toxicology, 1999. 18: p. 479-486.
5.Williams, G.M., Kroe, R., & Munro, I.C. Safety evaluation and risk assessment of the herbicide Roundup and active ingredient, glyphosate, for humans Regulatory Toxicology and Pharmacology, 200. 31: p. 117-165.
6.Tsui, M.T. & Chu, L.M. Aquatic toxicity of glyphosate based formulations: Comparisons between different organisms and the effect of environmental factors. Chemosphere, 2003. 52: p. 1189-1197.
7.Cox, C., Glyphosate (Roundup). Journal of Pesticide Reform, 1998. 18: p. 3-17.
8.Clive, J., The global status of the commercialized biotechnoligical/genetically modified crop: 2006. Tsitol. Genet., 2007. 41: p. 10-12.
9.Duffy, M., Does planting GMO seed boost farmer`s profits? Leopold Letter, 1999. 11: p. 1-5.
10.Benbrook, C.M. Genetically engineered crops and pesticide use in the United States. BioTech InfoNet Technical Paper Number 7, October 2004.
11.Nice, G., B. Johnson, and T. Bauman, A little burndown madness. Pest & Crop, 2008. 7.
12.Center for Food Safety. Agricultural pesticide use in U.S. agriculture: Why USDA-NASS agricultural chemical reporting is important. May 2008: Washington, DC.
13.Benachour, N. & Seralini, G.E. Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells. Chemical Research in Toxicology, In Press.
14.Ghanem, A., et al., Glyphosate and AMPA analysis in sewage sludge by LC-ESI-MS/MS after FMOC derivation on strong anion-exchange resin as solid support. Annals of Chemistry, 2007. 79: p. 3794-3801.
15.Cox, C. & Surgan, M. Unidentified inert ingredients in pesticides: Implications for human and environmental health. Environmental Health Perspectives, 2006. 114: p. 1803-1806.
16.Haefs, R., et al., Studies on a new group of biodegradable surfactants for glyphosate. Pesticide Management in Science, 2006. 58: p. 825-833.

About the author

Dr. Gregory Damato enjoys a raw vegan lifestyle and is the editor of which publishes the latest health and wellness news and information. The site attempts to facilitate in the expansion of human consciousness through unlocking our innate wisdom.

Get breaking news alerts on GMOs, fluoride, superfoods, natural cures and more...
Join over four million monthly readers. Email privacy 100% protected. Unsubscribe at any time.

Have comments on this article? Post them here:

comments powered by Disqus

Take Action: Support

Email this article to a friend

Permalink to this article:

Reprinting this article: Non-commercial use OK, cite with clickable link.

Embed article link: (copy HTML code below):
Most Popular
Today | Week | Month | Year

See all Top Headlines...


Now Available at

O3 Essentials OraJuvenate™
A powerful, cleansing dental cream for maximum oral/dental health.
New Cancer Solutions
Over 3 hours of content covering today’s best cancer tests, how to kill cancer cells and the best diets and exercise routines.
Freeze-Dried 100% Organic Whole Corn
Our freeze-drying method preserves taste, texture and nutrients better than any other food preservation method ever invented.
Fenix TK35 Flashlight
Tough, waterproof, extremely bright and it’s touted to throw an 800+ lumen beam more than 1,000 feet into the night.
Inca Treasure Smoothie Pack
This pack of our four most popular superfoods from South America is the perfect combo pack for smoothie lovers.
Pink Himalayan Salt
This salt delivers significant levels of magnesium, zinc and selenium, with trace levels of dozens of other elements.
Pinhole Glasses - Aviator Style
Pinhole glasses are becoming famous for helping people improve their vision without the risks of laser surgery.
Oxy-Rich Facial Serum
O3 Essentials Jojoba Oxy-Rich Facial Serum is cellular nourishment for your skin. Helps smooth fine lines while enhancing tissue elasticity.
Freeze-Dried 100% Blackberry Halves
Our freeze-dried blackberry halves are grown in Serbia under strict organic standards.

Also on NaturalNews:

Health Ranger Videos
Activist music
CounterThink Cartoons
Food documentaries
FREE Special Reports
Colloidal Silver

Advertise with NaturalNews...

Support NaturalNews Sponsors:

Advertise with NaturalNews...

Most Popular Stories

Flu shot kills 19-year-old, but vaccine industry still has total immunity against lawsuits
Here's a nutty fact: Eating more tree nuts lowers the risk of all-cause death by up to 20 percent
Six important facts you're not being told about lost Malaysia Airlines Flight 370
Malaysia Airlines Flight 370 now clearly a government cover-up: All evidence contradicts official story
10 other companies that use the same Subway yoga mat chemical in their buns
BLM fracking racket exposed! Armed siege and cattle theft from Bundy ranch really about fracking leases
High-dose vitamin C injections shown to annihilate cancer
U.S. treating meat with ammonia, bleach and antibiotics to kill the '24-hour sickness'
USDA to allow U.S. to be overrun with contaminated chicken from China
Vaccine fraud exposed: Measles and mumps making a huge comeback because vaccines are designed to fail, say Merck virologists
Battle for humanity nearly lost: global food supply deliberately engineered to end life, not nourish it
Diet soda, aspartame linked to premature deaths in women

25 Amazing Facts About Food

This FREE downloadable report unveils a collection of astonishing and little-known facts about the food we eat very day. Click here to read it now...


Resveratrol and its Effects on Human Health and Longevity - Myth or Miracle.

Unlock the secrets of cellular health with the "miracle" nutrient Resveratrol Click here to read it now...


Nutrition Can Save America

FREE online report shows how we can save America through a nutrition health care revolution. "Eating healthy is patriotic!" Click here to read it now...

The Healing Power of Sunlight and Vitamin D

In this exclusive interview, Dr. Michael Holick reveals fascinating facts on how vitamin D is created and used in the human body to ward off chronic diseases like cancer, osteoporosis, mental disorders and more. Click here to read it now...

Vaccines: Get the Full Story

The International Medical Council on Vaccination has released, exclusively through, a groundbreaking document containing the signatures of physicians, brain surgeons and professors, all of which have signed on to a document stating that vaccines pose a significant risk of harm to the health of children. Click here to read it now...

Health Ranger Storable Organics

GMO-free, chemical-free foods and superfoods for long-term storage and preparedness. See selection at

Recommended Resources On:

Natural News trends
Health Ranger news
Natural News GMOs
Mike Adams tracker
Natural News photos
Natural News Global
Natural News in focus
Natural News connect
Natural News shocking stories
Natural News radar
Health freedom
Dr. Paul Offit

This site is part of the Natural News Network © 2014 All Rights Reserved. Privacy | Terms All content posted on this site is commentary or opinion and is protected under Free Speech. Truth Publishing International, LTD. is not responsible for content written by contributing authors. The information on this site is provided for educational and entertainment purposes only. It is not intended as a substitute for professional advice of any kind. Truth Publishing assumes no responsibility for the use or misuse of this material. Your use of this website indicates your agreement to these terms and those published here. All trademarks, registered trademarks and servicemarks mentioned on this site are the property of their respective owners.

eTrust Pro Certified Android app on Google Play

Sign up for the FREE Natural News Email Newsletter

Receive breaking news on GMOs, vaccines, fluoride, radiation protection, natural cures, food safety alerts and interviews with the world's top experts on natural health and more.

Join over 7 million monthly readers of, the internet's No. 1 natural health news site. (Source:

Your email address *

Please enter the code you see above*

No Thanks

Already have it and love it!

Natural News supports and helps fund these organizations:

* Required. Once you click submit, we will send you an email asking you to confirm your free registration. Your privacy is assured and your information is kept confidential. You may unsubscribe at anytime.