Subscribe (free)
About NaturalNews
Contact Us
Write for NaturalNews
Media Info
Advertising Info
Prostate cancer

Common Prostate Cancer Treatment Causes Cancer to Spread Throughout Body

Tuesday, March 04, 2008 by: David Gutierrez, staff writer
Tags: prostate cancer, health news, Natural News

Most Viewed Articles
Popular on Facebook
(NaturalNews) Androgen deprivation therapy, commonly used in the treatment of prostate cancer, may actually make cancer more likely to spread to other parts of the body, according to a study conducted at Johns Hopkins University School of Medicine and published in the journal Cancer Research.

Because prostate tumor growth is generally stimulated by male sex hormones, androgen deprivation therapy, in which those hormones are suppressed, is often given to patients in order to slow tumor growth.

Prior research has demonstrated that a protein called nestin tends to be produced by prostate cancer cells that have metastasized to other parts of the body. Nestin does not appear to be produced by cancer cells, however, in cases where the cancer has not spread.

Researchers experimented on androgen-dependent prostate cancer cells in the laboratory. When they cut off the cells' access to androgens, the cells increased their production of nestin.

The researchers then use the technique known as RNA interference to make the cancer cells less able to produce nestin. When the cells were transplanted into the bodies of mice, they were found to be less likely to spread to other locations than unmodified cells were. The nestin-production-hampered cells were also found to have a decreased ability to move through or around other cells when compared with unmodified prostate cancer cells.

The researchers did not find any evidence that levels of nestin had any impact on tumor growth.

"What all this suggests is that nestin levels increased when prostate cancer cells are deprived of androgens and may encourage the cells to metastasize," said researcher David Berman.

But the researchers warned that there is not yet enough evidence to advise the abandonment of androgen deprivation therapy as a treatment.

The study was funded by the Evensen Family Foundation, the German Cancer Foundation, the National Cancer Institute and the National Institutes of Health.
STAY INFORMED! Free subscription to the Health Ranger's email newsletter
Get breaking news alerts on GMOs, fluoride, superfoods, natural cures and more...
Join over four million monthly readers. Your privacy is protected. Unsubscribe at any time.
comments powered by Disqus

Sign up for the FREE Natural News Email Newsletter

Receive breaking news on GMOs, vaccines, fluoride, radiation protection, natural cures, food safety alerts and interviews with the world's top experts on natural health and more.

Join over 7 million monthly readers of NaturalNews.com, the internet's No. 1 natural health news site. (Source: Alexa.com)

Your email address *

Please enter the code you see above*

No Thanks

Already have it and love it!

Natural News supports and helps fund these organizations:

* Required. Once you click submit, we will send you an email asking you to confirm your free registration. Your privacy is assured and your information is kept confidential. You may unsubscribe at anytime.