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The protein, potato proteinase inhibitor 2 (PI2), developed by Kemin Health is derived from white potatoes, and is one of the main ingredients in the weight loss supplement, Slendesta.

A recent study, conducted at Iowa State University, has shown that when an individual ingests PI2, the release of a cholecystokinin, a peptide that simulates the feeling of fullness, is stimulated.

The largest study in a series to test the weight loss potential of PI2 involved some 240 participants, and spanned 12 weeks. Participants who were given 30 mg of PI2 one hour before the two largest meals of the day showed marked weight loss over participants who had been given a placebo.

"This potato protein extract looks promising as a safe, natural appetite suppressant," said Mike Adams, co-author of "Natural Appetite Suppressants for Safe, Effective Weight Loss." "In my personal testing so far, I have found it helps take the edge off of late night hunger, especially when combined with pinolenic acid."

Pinolenic acid is an appetite suppressant and digestive aid derived from the pine nuts of the Siberian pine.

No study on either animal or human toxicity has yielded any evidence yet that consumption of PI2 has any adverse effects.

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