Summary

Original source:
http://go.reuters.com/newsArticle.jhtml?type=healthNews&storyID=10795311&src=rss/healthNews

Details

• Correcting vitamin D deficiency could significantly lower the risk of several types of cancer, investigators report.
• "The cost of a daily dose of vitamin D3 (1000 IU) is less than 5 cents, which could be balanced against the high human and economic costs of treating cancer attributable to insufficiency of vitamin D," they point out.
• Vitamin D can reduce the risk of many types of cancer by block the growth of new blood vessels that allow cancer to thrive, a process known as angiogenesis.
• It can also stimulate cell adherence and "enhance intercellular communication through gap junctions, thereby strengthening the inhibition of cancer cell growth that results from tight physical contact with adjacent cells within a tissue," Dr. Cedric F. Garland and colleagues note in their article, published in the current issue of the American Journal of Public Health.
• Garland, from the University of California, San Diego in La Jolla, and his colleagues performed a search of published studies, identifying 63 observational studies on vitamin D and its association with cancers of the colon, breast, prostate and ovary.
• Twenty of 30 studies of colon cancer or precancerous colon polyps found a statistically significant benefit of vitamin D. Similar results were observed for 9 of 13 studies concerning breast cancer risk, 13 of 16 studies concerning prostate cancer risk, and 5 of 7 studies concerning ovarian cancer.
• The authors recommend supplementing the diet with 800 to 1000 IU vitamin D per day, and believe that dosages up to 1000 IU per day would not produce toxicity.

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