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Original source:
http://www.usatoday.com/news/health/2003-10-14-nasal-spray-overeating_x.htm

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• Researchers are racing to investigate a nasal spray and other forms of a hormone medication that may help dieters eat less because they aren't as hungry.
• The drug contains a formulation of PYY, a hormone that's produced by the gut and travels to the brain to shut down neurons that regulate appetite.
• It's potentially "very promising as a therapeutic agent," says researcher Stephen Bloom of the Imperial College of Medicine in London.
• His studies indicate that the drug works in both lean and obese people, who seem to have lower levels of PYY.
• That may explain why heavy people feel hungry and overeat.
• Those who take the medication "enjoy their meal, but they stop eating sooner," he says.
• So far the drug has had no negative side effects, Bloom says.
• He discussed his work Tuesday in Fort Lauderdale at the annual meeting of the North American Association for the Study of Obesity.
• He has studied an injected version of PYY and is now looking at the spray form.
• A patch is another option, but pills won't work because they're digested.
• The PYY nasal spray must still go through a couple of years of rigorous testing, says Steven Quay of Nastech Pharmaceutical Company, the drug's maker.
• Samuel Klein, president of the North American Association for the Study of Obesity, says the research "looks very impressive."

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