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Originally published March 26 2005

New weight loss nasal spray may help users stop eating sooner

by Mike Adams, the Health Ranger, NaturalNews Editor

A new spray currently being tested appears to spur weight loss by curbing appetites, its makers say. The drug contains a hormone that travels from the belly to the brain were it regulates the appetite. The spray may reduce appetites by up to 30 percent per day, experts say. The maker of the drug, Nastech Pharmaceutical Co, has just begun testing the spray which is at least two years away from being on the market.



Sign up to receive our free Daily Briefing e-newsletter and get the top news of the day in your inbox. Researchers are racing to investigate a nasal spray and other forms of a hormone medication that may help dieters eat less because they aren't as hungry. The drug contains a formulation of PYY, a hormone that's produced by the gut and travels to the brain to shut down neurons that regulate appetite. It's potentially "very promising as a therapeutic agent," says researcher Stephen Bloom of the Imperial College of Medicine in London. His studies indicate that the drug works in both lean and obese people, who seem to have lower levels of PYY. That may explain why heavy people feel hungry and overeat. Those who take the medication "enjoy their meal, but they stop eating sooner," he says. So far the drug has had no negative side effects, Bloom says. He discussed his work Tuesday in Fort Lauderdale at the annual meeting of the North American Association for the Study of Obesity. He has studied an injected version of PYY and is now looking at the spray form. A patch is another option, but pills won't work because they're digested. The PYY nasal spray must still go through a couple of years of rigorous testing, says Steven Quay of Nastech Pharmaceutical Company, the drug's maker. Samuel Klein, president of the North American Association for the Study of Obesity, says the research "looks very impressive."


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