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Originally published February 15 2006

Dutch study determines certain motor symptoms predict Parkinson's

by Mike Adams, the Health Ranger, NaturalNews Editor

The Archives of Neurology has published a study from a team of researchers at the Erasmus Medical Center in Rotterdam, where the team discovered that certain motor symptoms in the elderly, including stiffness, tremors and loss of balance, may indicate an increased risk of developing Parkinson's Disease.



Elderly people who complain of stiffness, loss of balance and tremors may be at increased risk for future Parkinson's disease (PD), according to a study posted online today that will appear in the April 2006 print issue of Archives of Neurology, one of the JAMA/Archives journals. PD develops over time as neurons in certain areas of the brain that control muscle movement slowly waste away, according to background information in the article. Typical symptoms of PD--including severe tremors, rigidity and slow movements--begin when the brain loses more than half of its dopamine production ability. The participants answered questions about their motor skills, including whether they had experienced stiffness, tremors, falling, slowness or a feeling of imbalance. More than half of them reported at least one of these complaints. They were then assessed for PD at two follow-up visits and their medical records were analyzed. "Our findings support the notion that clinically manifest PD is preceded by a preclinical phase that is not entirely asymptomatic," the authors report. "Subjective complaints related to motor function might indicate a very early phase of not-yet-diagnosable PD during which dopamine loss is not sufficient to produce overt typical PD symptoms but may result in subtle signs that are very mild or only intermittently present and therefore not likely to be detected in routine screening or examination." Since such a large percentage of elderly people report these motor symptoms and a relatively small percentage of them go on to develop PD, it's unlikely that screening for these complaints alone would be effective in detecting the disease, the authors report. However, as researchers continue work to pinpoint biological markers of PD, assessing these types of complaints might help narrow down candidates for brain imaging, psychological testing or other methods of early diagnosis, they conclude.


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