Originally published October 28 2005
Study shows high error rate in chemotherapy orders
by Mike Adams, the Health Ranger, NaturalNews Editor
Cancer, The Journal of the American Cancer Society, has published a study that found a serious error in one out of every 50 chemotherapy orders, leading researchers to recommend that stronger safety controls be put in force at infusion clinics.
Medication errors in hospitals are a stark reminder of the potential harm that can occur when patients are admitted to the hospital.
While most medications are well tolerated, a few classes are toxic and require complex dosing regimens, such as those used in chemotherapy.
Even a low error rate from these medications could potentially lead to significant harm, including death.
Aside from a few case reports in journals and popular media, little research has investigated the error rate of chemotherapy orders at outpatient clinics or hospitals.
Some individual institutions that have been affected by these reported errors, such as the Dana-Farber Cancer Institute (a member of the Dana-Farber/Harvard Cancer Center, a National Cancer Institute-designated comprehensive cancer center), have made extensive changes to prevent such errors, such as computerization of the medication ordering system.
Led by Tejal K. Gandhi, M.D., M.P.H. and Sylvia B. Bartel, R.Ph., M.H.P., researchers from the Brigham and Women's Hospital, the Dana-Farber Cancer Institute, and the Harvard School of Public Health reviewed over 10,100 medication orders from one pediatric and two adult ambulatory clinics, which used either a paper or computerized medication ordering system.
The researchers used a strict definition of error and counted any mistake in the medication process, including ordering, dispensing, transcribing, administering, and monitoring.
The review of orders demonstrated an overall medication error rate of three percent and a serious error rate of two percent, less than the five percent rate on all orders identified in previous studies.
Categorized according to the severity of the error, 82 percent of the errors in adults and 60 percent in children had the potential to cause an adverse drug event (ADE) had they reached a patient.
In the adult clinics, which used a computerized ordering system, the most frequent errors were due to omission of dosages and orders not being discontinued.
In the pediatric clinic, which used a paper-based ordering system, the most frequent errors were due to orders not being discontinued and incorrect dosages.
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