Originally published July 15 2005
Breast cancer risk may be increased by long-term aspirin use
by Mike Adams, the Health Ranger, NaturalNews Editor
Television commercials have latched on to the fact that a daily regimen of aspirin can increase heart health, but, according to University of Southern California researchers, consistent use of aspirin and ibuprofen by women may increase their risk of developing certain types of breast cancers.
Women who take ibuprofen or aspirin daily for several years might face a higher risk of certain breast cancers, according to preventive medicine researchers in the Keck School of Medicine of USC.
Published in the June 1 issue of the Journal of the National Cancer Institute, study findings indicate that women using ibuprofen every day for five years or longer were more than 50 percent more likely than non-users to be diagnosed with breast cancer, while women using aspirin every day for five years or longer were more than 81 percent more likely than non-users to be diagnosed with a certain sub-type of breast cancer.
There are no reasons we know of for certain, biologically, that would explain that, but findings suggest this area merits further study," said Sarah Marshall, researcher in the department of preventive medicine in the Keck School and the study's lead author.
"The most important conclusion from this study is that we found little evidence that aspirin or other NSAID use reduce breast cancer risk, as suggested by other recent studies," Ross said.
"In comparison to other studies, our study was very large and statistically very powerful."
Marshall and her colleagues analyzed data on 114,460 women participating in the California Teachers Study, an expansive examination of cancer among female teachers that is led by researchers at the Keck School and USC/Norris Comprehensive Cancer Center.
The researchers asked women about their use of NSAIDs, among many other lifestyle factors.
Researchers looked for any relationships between the use of pain medication and breast cancer risk in participating women.
The COX-2 gene kicks into gear in wounded or inflamed tissue, so suppressing the gene's expression (through NSAIDs) can lower inflammation and associated pain.
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