Originally published June 28 2005
Some patients experience emotional relief from placebos
by Mike Adams, the Health Ranger, NaturalNews Editor
Just as placebos (inactive medications with an effect determined by the psychology of the user) have been found to give relief from physical pain, Science Daily reports that Karolinska Institute researchers have seen patients better able to deal with anxiety when a placebo was administered.
In their experiments, the researchers tested the effect of placebo treatment on volunteer subjects' ratings of unpleasant pictures, such as images of mutilated bodies.
Other researchers had shown that people's expectation of pain relief plays a major role in the effectiveness of placebos.
So, in their experiments, the researchers first induced such an expectation in the subjects by administering an antianxiety drug to reduce the subjects' unpleasant perception of the pictures.
This scanning technique uses harmless magnetic fields and radio waves to measure blood flow in brain regions, which reflects brain activity.
Importantly, the fMRI scans showed that the placebo reduced activity in the brain's emotional centers, and this reduction correlated with a subject's amount of reduction in the rated unpleasantness of the pictures.
That is, the subjects who reported the largest placebo response also showed the largest decrease in activity in the emotional centers.
Also importantly, the placebo increased brain activity in the same "modulatory network" whose activity is increased when placebos have been used to relieve pain.
Those subjects who expected the largest effect--as measured by the effect they reported from the real antianxiety drug the previous day--showed the largest changes in activity in the emotional and modulatory areas.
"The present data demonstrate that emotional experience may be modulated through a placebo treatment in a similar manner as has been previously reported for pain perception," concluded Petrovic and his colleagues.
They wrote that the study "demonstrated that very similar mechanisms are involved in the placebo response of emotional stimuli and in placebo analgesia, thereby generalizing the concept of placebo and its associated underlying neural processes."
They also concluded that the placebo effect can be thought of "as a general process of modulation induced by the subjects' expectations, possibly using specific modulating systems."
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