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Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well

Elaine Magee
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Lutein and zeaxanthin may slash the risk of non-Hodgkin's lymphoma. The results of a new study in the American Journal of Clinical Nutrition suggest that high daily intake of the carotenoids lutein and zeaxanthin cuts the risk of non-Hodgkin's lymphoma by almost 50 percent. (Whenever something decreases risk by half, that gets my attention.) The researchers found that people with the highest intake of lutein and zeaxanthin had a 46 percent lower risk, compared with people with the lowest intake.

PDR for Herbal Medicines, Fourth Edition

Thomson Healthcare, Inc.
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Within the central macula, zeaxanthin is the dominant component (up to 75%), whereas in the peripheral retina, lutein predominates (greater than 67%). The macular concentration of lutein and zeaxanthin is so high that they are visible as a dark yellow spot called the macular pigment. Because these carotenoids are powerful antioxidants and absorb blue light, researchers have hypothesized that they protect the retina. While both are abundant in green and yellow fruits and vegetables, lutein is the carotenoid most often used as a supplement.

Nutrition in the Prevention and Treatment of Disease

Ann M. Coulston and Carol J. Boushey
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Retinal zeaxanthin has been demonstrated to prevent light-induced photoreceptor death in quail [150]. Lower levels of lutein and zeaxanthin have been found in autopsy specimens of donor eyes with AMD [145]. However, to date, cross-sectional relationships of AMD to macular pigment density, measured noninvasively in living persons, are inconsistent [151-154] and likely to reflect relationships of AMD to short-term diet rather than diet over decades of adult life when AMD was likely to develop.
Lycopene but not lutein nor zeaxanthin decreases in serum and lipoproteins in age-related macular degeneration patients. Clinica Chimica Acta 357, 34-42. 129. Gale, C. R., Hall, N. F., Phillips, D. I., and Martyn, C. N. (2003). Lutein and zeaxanthin status and risk of age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 44, 2461-2465. 130. Moeller, S. M., Parekh, N., Tinker, L., et al. (2006).

PDR for Herbal Medicines, Fourth Edition

Thomson Healthcare, Inc.
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Intake of lutein/ zeaxanthin were inversely correlated with pigment abnormalities in at-risk individuals aged 40 to 59 and late AMD in at-risk individuals aged 60 to 79. A direct correlation was reported between intake of lutein/zeaxanthin and soft drusen (the most common type of early AMD). This finding was inconsistent with other evidence and may be due to increases in intake of fruits and vegetables as a result of diagnosed retinal abnormalities (Mares-Perlman et al 2001).

Nutrition in the Prevention and Treatment of Disease

Ann M. Coulston and Carol J. Boushey
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In another trial, data suggest that lutein or zeaxanthin supplementation may improve visual performance at low illumination [165]. However, in another small trial, supplementation did not improve contrast sensitivity over 9 months [166]. Larger and longer-term trials are needed to address potential benefits (and risks) of supplementation with lutein and zeaxanthin more conclusively. A large multicenter trial of these carotenoids (and omega-3 fatty acids) on progression of advanced AMD (AREDS II) is currently under way [167].
SUB, Omg/d cholesterol, 0 p:g lutein + zeaxanthin) diet for 30 days. The two arms of the dietary intervention were separated by a 3-week washout period. Plasma concentrations of total cholesterol, LDL cholesterol (LDL-C), and HDL cholesterol were determined. Because eggs are an excellent source of lutein and zeaxanthin, the plasma levels of these carotenoids were also measured in a subset of subjects to determine whether the response to carotenoid intake was similar to that seen for dietary cholesterol and to evaluate the contribution of ABCG5 polymorphism to both responses.

The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why

Jonny Bowden, Ph.D., C.N.S.
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Lutein and its related compound, zeaxanthin, are highly concentrated in the macula, providing a yellow color known as the macular pigment, which protects the macula. You want that pigment to be dense, the better to protect your eyes. A 1997 study found that subjects fed a diet high in spinach and corn experienced nearly a 20 percent increase in macular pigment density. What's the connection with those foods? That diet effectively boosted the subjects' consumption of lutein about 400 percent and zeaxanthin about 300 percent.

Feed Your Genes Right: Eat to Turn Off Disease-Causing Genes and Slow Down Aging

Jack Challem
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Lutein and Zeaxanthin Lutein and zeaxanthin, found in kale, spinach, and broccoli, also serve as antioxidant carotenoids. They are deposited in the macula, the center of the eye's retina, responsible for detailed vision.These yellowish deposits of lutein and zeaxanthin are referred to as the macular pigment, and they help filter out harmful wavelengths of light. This area of pigment, smaller than the head of a pin, also functions somewhat like a pair of polarized sunglasses, improving visual acuity in bright situations.

The Detox Strategy: Vibrant Health in 5 Easy Steps

Brenda Watson and Leonard Smith
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You might also find antioxidant complexes with ingredients such as grapeseed extract, pine bark, blueberry extract, zeaxanthin, and astaxanthin. Astaxanthin, derived from algae, is believed to be several hundred times more effective than vitamin E in neutralizing free radicals. Where minerals are concerned, in addition to the macrominerals (those needed in large amounts), such as calcium and magnesium, you'll also want to select a formula that has a wide range of trace minerals (those needed in small quantities), such as selenium, vanadium, chromium, boron, and iodine.

The Desktop Guide to Herbal Medicine: The Ultimate Multidisciplinary Reference to the Amazing Realm of Healing Plants, in a Quick-study, One-stop Guide

Brigitte Mars, A.H.G.
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Constituents Carotene, vitamin Bi, vitamin C, essential oils (limo-nene, linalool, nerol, geraniol), flavonoids (hesperidin, zeaxanthin, cryptoxanthin), aldehydes, coumarins, bitters (naringine, aurantiamarine), synephrine Energetic Correspondences • Flavor: pungent, bitter (except for C. x aurantium, which is sour and bitter) • Temperature: warm (except for C. x aurantium, which is cool) • Moisture: dry • Polarity: yang • Planet: Sun/Neptune • Element: fire Contraindications Use bitter orange with caution during pregnancy, as large doses may stimulate contractions.
Constituents Essential oils (cineole, safranal, pinene), bitter glycoside (crocin), glucoside (picrocrocin), carotenoids (carotene, lycopene, zeaxanthin), vitamins Bj and B2 Energetic Correspondences • Flavor: bitter, sweet, pungent • Temperature: neutral • Moisture: dry • Polarity: yang • Planet: Sun • Element: fire Contraindications Long-term use may damage the kidneys and central nervous system. Large doses may cause coughs or headache; they can be narcotic and even potentially lethal. Avoid therapeutic doses during pregnancy.
Constituents Berry, seed: beta-carotene, lycopene, zeaxanthin, vitamin B complex (Bl5 B2, Bg, and folic acid), vitamin E, flavonoids (quercitin), essential fatty acids (omega-3, omega-6, omega-7, omega-9), quinic acid, malic acid, phytosterols (beta-sitosterol) Leaf, twigs: tannins Energetic Correspondences • Flavor: sour • Temperature: cool • Moisture: moist • Polarity: yin • Planet: Moon/Mars/Jupiter/Saturn • Element: water Contraindications In rare cases sea buckthorn may cause an allergic reaction.
Constituents Flavonoids (rutin, zeaxanthin), alkaloids (protopine, allocryptine, berberine, sanguinarine) Energetic Correspondences • Flavor: bitter • Temperature: cool • Moisture: dry • Polarity: yin • Planet: Sun/Mercury • Element: air Contraindications Avoid in cases of depression. Excess use can cause one to feel hung over in the morning. Range and Appearance California poppy, a perennial or hardy annual, is native to the southwestern United States; in fact, it is the state flower of California. It grows wild in sunny areas, reaching a height of 1 to 3 feet.

101 Foods That Could Save Your Life!

David W. Grotto, RD, LDN
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Spinach is especially high in vitamin A and related compounds such as beta-carotene, zeaxanthin, and lutein, carotenoids that act as protection for the eye. Spinach is one of the richest sources of lutein, containing nearly 30,000 micrograms per cup of frozen spinach. Spinach is also rich in glycolipids, powerful phytochemicals known to have cancer cell growth suppression and antiproliferation qualities. Home Remedies Eating some cooked spinach every day is supposed to be helpful in relieving depression and neuritis, an inflammation of the nerves, because of spinach's high B-vitamin content.
Chard contains the carotenoids zeaxanthin and lutein, which benefit vision. Home Remedies Chard has been used for the treatment of ulcers, tumors, leukemia, and other cancers. In South Africa, the drinking of chard juice is supposed to ease the discomfort of hemorrhoids. Chard juice has also been used as a decongestant and to neutralize stomach acidity. Throw Me a Lifesaver! CANCER: Components in chard were found to inhibit cell proliferation of human cancer cells.
However, its concentration of the plant chemicals beta-carotene and zeaxanthin more than makes up for any shortfall in nutrient density. Home Remedies Whatever ails you! Goji has been used to treat inflammations, skin irritations, nosebleeds, and aches and pains. In Chinese medicine, goji is recommended for long life, sharp eyesight, and healthy liver function, to boost sperm production, and to improve circulation, among other benefits. Throw Me a Lifesaver!
DECREASED RISK OF AGE-RELATED MACULAR DEGENERATION: Phytochemicals such as lutein, cryptoxanthin, and zeaxanthin, present in papaya, may help maintain better eyesight longer in older people. Tips on Using Papaya SELECTION AND STORAGE: • Papayas that are hard and green are immature and will never properly ripen. Look for papayas that are mostly or completely yellow. • The papaya should give slightly to pressure, but should not be soft at the stem end. • Avoid buying fruit that is bruised, shriveled, or has soft spots.

The 150 Healthiest Foods on Earth: The Surprising, Unbiased Truth About What You Should Eat and Why

Jonny Bowden, Ph.D., C.N.S.
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For that you get some folate (folic acid), vitamin A, and a surprisingly decent amount of the extremely eye-healthy carotenoids, lutein and zeaxanthin. There's also about the same amount of calcium as there is in spinach, but arugula is actually lower in oxalates, a substance that inhibits calcium absorption. Arugula has a nice amount of vitamin K: One cup contains almost half the recommended daily allowance (which in my opinion is too low). Vitamin K is essential for clotting and is a key player in developing strong bones.

Superfoods Rx Diet: Lose Weight with the Power of SuperNutrients

Wendy Bazilian, DRPH, MA, RD, Steven Pratt, MD, Kathy Matthews
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In spinach, just as one example, the somewhat amazing array of phytonutrients includes the carotenoids lutein, zeaxanthin, and beta-carotene among many others. We mentioned the concept of synergy earlier. Spinach is an excellent example of synergy in a particular SuperFood. It's the power of all the nutrients working in concert that makes spinach and the other SuperFoods such standouts in the world of nutrition.

Unleash the Inner Healing Power of Foods

The Editors of FC&A
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The richest source of zeaxanthin is the orange bell pepper. All sweet peppers are packed with nutrients, but more of the orange pepper's carotenoids are zeaxanthin than anything else. When selecting peppers, avoid those with poor color or bruises. Keep them refrigerated in a covered container or bag, and they'll also last up to a week. Shop for cantaloupes. Like carrots, cantaloupes are rich in vitamin C and beta carotene. These all-star antioxidants help protect your retina from free radical damage and keep the blood vessels in your eye healthy.

If you exercise, be sure to increase your uptake of nutritional supplements and superfoods

Mike Adams, the Health Ranger
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Those include various carotenoids like beta keratin or zeaxanthin, lutein, anthocyanidins, Proanthocyanidins like those found in grape seeds or even Resveratrol found in grape skin. There are hundreds, actually thousands, of different phytonutrients found in foods and nutritional supplements. These are also very important to get into your body when you follow an intense physical exercise program. Eating raw nuts and seeds, I think, is also extremely important.

Product Review: New natural health products

Mike Adams, the Health Ranger
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Loaded with zeaxanthin, bilberry and ginkgo, it's a super nervous system protector and enhancer. (It also happens to put antioxidants into your skin that help protect you from sunburn.) It's outstanding for eye health and has numerous other benefits. Juvo raw meal now available in 21 oz. containers The Juvo Natural Raw Meal product (www.GoJuvo.com) is now available in a more affordable 21-oz. canister. In the world of underground cures, Juvo is known as the anti-cancer meal that actually tastes good.

101 Foods That Could Save Your Life!

David W. Grotto, RD, LDN
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It is also a good source of the carotenoids lutein, zeaxanthin, and beta-carotene. Home Remedies Ancient Greeks applied oregano leaves to soothe aching muscles. The Romans would use oregano for scorpion and spider bites. In the United States, oregano was used for chronic coughs, asthma, and to help relieve toothaches. Men turned to a mixture of olive oil and oregano as a scalp treatment in hopes of revitalizing hair growth. The same olive oil and oregano combination has been applied to rheumatic limbs and sprains with success. (At least, with greater success than as a cure for baldness.

The 150 Healthiest Foods on Earth: The Surprising, Unbiased Truth About What You Should Eat and Why

Jonny Bowden, Ph.D., C.N.S.
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Both lutein and zeaxanthin are members of the carotenoid family and are being extensively researched for their demonstrated ability to prevent or reduce macular degeneration, the number-one cause of adult blindness. Watercress Neutralizes Carcinogens The health benefits of watercress have been known since ancient times. Watercress is a member of the family of vegetable superstars, the brassica family of cruciferous vegetables, which counts among its members such vegetable royalty as broccoli, cabbage, kale, kohlrabi, and Swiss chard.

The Encyclopedia of Healing Foods

by Michael Murray, N.D. and Joseph Pizzorno, N.D.
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However, various "nonessential" food components, such as the carotenes lutein, zeaxanthin, and lycopene, along with flavonoids, are proving to be even more significant in protecting against ARMD than traditional nutritional antioxidants, such as vitamin C, vitamin E, and selenium. The macula, especially the central portion (the fovea), owes its yellow color to its high concentration of lutein and zeaxanthin.

Earl Mindell's Supplement Bible: A Comprehensive Guide to Hundreds of NEW Natural Products that Will Help You Live Longer, Look Better, Stay Heathier, ... and Much More!

Earl Mindell, R.Ph., Ph.D.
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If you don't regularly eat these foods, you should consider taking a carotenoid supplement with zeaxanthin, or one of the new combination formulas designed to enhance vision that includes zeaxanthin. Because of its antioxidant properties, zeaxanthin may also protect against various forms of cancer that can be initiated by free radical activity. In fact, preliminary studies show that zeaxanthin can decrease the rate of growth of tumor cells. Possible Benefits Helps protects against macular degeneration. May help prevent cancer. The Right Amount Take 30 to 130 mg.

PDR for Herbal Medicines, Fourth Edition

Thomson Healthcare, Inc.
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A multivariate risk analysis showed that the highest quintile intake of lutein (>5,921 meg of lutein daily for women and 6,701 meg daily for men) was associated with a nonsignificant 19% reduction in lung cancer risk compared with the lowest quintile intake, based on pooled results from two prospective United States cohort studies (Michaud et al 2000): In addition, lutein/ zeaxanthin intake of >7,162 meg daily was associated with a 53% reduction (p=0.
The ranking (greatest to least) was lycopene, alpha-tocopherol, alpha carotene, beta-cryptoxanthin, zeaxanthin, beta-carotene, and lutein (Stahl et al, 1998). Lycopene was not associated with a reduced risk of nuclear cataracts in the aged. Lycopene has been shown to have a protective antioxidant effect on cataracts in experimental animals. A nuclear opacity test was done using lens photographs taken in 1988 to 1990 and compared to photographs taken in 1993 to 1995. Nonfasting concentrations of various carotenoids and tocopherols were determined from serum obtained at baseline.
Kim HP, Kim SY, Lee EJ, Kim YC, Kim YC, zeaxanthin dipalmitate from Lycium chinense has hepatoprotective activity. Res Commun Mol Pathol Pharmacol, 97:301-14, Sep. 1997 Kim SY, Choi YH, Huh H, Kim J, Kim YC, Lee HS, New antihepatotoxic cerebroside from Lycium chinense fruits. J Nat Prod, 60:274-6, Mar. 1997 Lin CC, Chuang SC, Lin JM, Yang JJ. Evaluation of the antiinflammatory hepatoprotective and antioxidant activities of Lycium chinense from Taiwan. Phytomedicine 4 (3); 213-220. 1997 Morita H, Yoshida N, Takeya K, Itokawa H, Shirota O.

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