Mike Adams
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 The use as rat poison is now declining because many rat populations have developed resistance to warfarin.
Warfarin: Rats vs. People
1 warfarin = Poison
Warfarin = Medicine 1
Warafin, used to control rat and mice populations as an odorless poison, becomes the "medicine" Coumadin when prescribed to people.
Here's a reasonable question to ask, then: If warfarin is deadly to rats, why is it supposedly good for humans?
Warfarin actually interferes with vitamin K metabolism. |
by Michael Murray, N.D. and Joseph Pizzorno, N.D.
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| Green tea can interfere with the blood thinner warfarin (Coumadin). This drug blocks blood clotting in part by interfering with the actions of vitamin K. Since green tea is a significant source of vitamin K, it may reduce the effectiveness of warfarin. However, warfarin can effectively be used even if you drink green tea, as long as the quantities you drink remain constant from day to day. The standard blood tests done when you are taking warfarin will show any effects from the extra vitamin K contained in green tea, and your doctor can simply adjust the warfarin dose to compensate. |
Mike Adams
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| The anticoagulant medication Coumadin, for example, is known generically as warfarin. This warfarin drug was originally developed not as a medication, but as rat poison! It sounds unbelievable, but it's true. Here's an entry on warfarin found at Wikipedia:
Warfarin is used as a rodenticidefor controlling rats and mice in residential, industrial, and agricultural areas. It is both odorless and tasteless. |
Andreas Moritz
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 Cases of minor bleeding complications were primarily seen among the aspirin and warfarin group.
• Patients in the aspirin therapy group were twice as likely as the patients in the warfarin group to face hospitalization for cardiovascular complications, particularly worsening cases of heart failure during the first 12 months following the study.
• warfarin proved to be ineffective and should be eliminated as a treatment option. |
Mike Adams
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| People
1 warfarin = Poison
Warfarin = Medicine 1
Warafin, used to control rat and mice populations as an odorless poison, becomes the "medicine" Coumadin when prescribed to people.
Here's a reasonable question to ask, then: If warfarin is deadly to rats, why is it supposedly good for humans?
Warfarin actually interferes with vitamin K metabolism. |
Andreas Moritz
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| The subjects were divided into three groups, aspirin therapy, warfarin therapy and no antithrombotic therapy.
Results of the Study
• Aspirin and warfarin didn't provide the patients with any valuable health benefits.
• There didn't appear to be any substantial differences of incidences of death, nonfatal heart attacks or nonfatal stroke in the three groups of the study.
• Patients in the aspirin group had increased chances of experiencing serious gastrointestinal problems.
• Cases of minor bleeding complications were primarily seen among the aspirin and warfarin group. |
by Michael Murray, N.D. and Joseph Pizzorno, N.D.
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| Since green tea is a significant source of vitamin K, it may reduce the effectiveness of warfarin. However, warfarin can effectively be used even if you drink green tea, as long as the quantities you drink remain constant from day to day. The standard blood tests done when you are taking warfarin will show any effects from the extra vitamin K contained in green tea, and your doctor can simply adjust the warfarin dose to compensate.
Virtually all forms of tea contain high levels of oxalate. |
Mike Adams
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| The anticoagulant medication Coumadin, for example, is known generically as warfarin. This warfarin drug was originally developed not as a medication, but as rat poison! It sounds unbelievable, but it's true. Here's an entry on warfarin found at Wikipedia:
Warfarin is used as a rodenticidefor controlling rats and mice in residential, industrial, and agricultural areas. It is both odorless and tasteless. |
Joerg Gruenwald, Ph.D.
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 Drug Interactions: There has been some documented interactions with warfarin. Papaya extract has been shown to increase the international normalized ratio (INR) levels when used in conjunction with warfarin.
CARICAE PAPAYAE FOLIUM
No health hazards or side effects are known in conjunction with the proper administration of designated therapeutic dosages.
DOSAGE
Daily Dosage: No information is available.
LITERATURE
PAPAJNUM CRUDUM
Buttle DJ et al., Affinity purification of the novel cysteine proteinase papaya proteinase IV, and papain from papaya latex. In: Biochem J 261(2):469-476. 1989. |
Andreas Moritz
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| Patients in the aspirin therapy group were twice as likely as the patients in the warfarin group to face hospitalization for cardiovascular complications, particularly worsening cases of heart failure during the first 12 months following the study.
• warfarin proved to be ineffective and should be eliminated as a treatment option.
Popular medications such as aspirin, ibuprofen and acetaminophen can raise blood pressure and raise the risk of heart disease among men, according to findings published in the Archives of Internal Medicine. |
| Results of the Study
• Aspirin and warfarin didn't provide the patients with any valuable health benefits.
• There didn't appear to be any substantial differences of incidences of death, nonfatal heart attacks or nonfatal stroke in the three groups of the study.
• Patients in the aspirin group had increased chances of experiencing serious gastrointestinal problems.
• Cases of minor bleeding complications were primarily seen among the aspirin and warfarin group. |
| Patients in the aspirin therapy group were twice as likely as the patients in the warfarin group to face hospitalization for cardiovascular complications, particularly worsening cases of heart failure during the first 12 months following the study.
• warfarin proved to be ineffective and should be eliminated as a treatment option.
Popular medications such as aspirin, ibuprofen and acetaminophen can raise blood pressure and raise the risk of heart disease among men, according to findings published in the Archives of Internal Medicine. |
by Michael Murray, N.D. and Joseph Pizzorno, N.D.
See book keywords and concepts |
| However, warfarin can effectively be used even if you drink green tea, as long as the quantities you drink remain constant from day to day. The standard blood tests done when you are taking warfarin will show any effects from the extra vitamin K contained in green tea, and your doctor can simply adjust the warfarin dose to compensate.
Virtually all forms of tea contain high levels of oxalate. Individuals with a history of calcium oxalate-containing kidney stones should limit their consumption of this food. See page 787 for more information. |
Thomson Healthcare, Inc.
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| MODERATE RISK
Anticoagulants: In one case report, Panax ginseng was suspected to have caused a decrease in INR in a patient previously stabilized on warfarin (Janetsky & Morreale, 1997). Clinical Management: Avoid Ginseng use with anticoagulants if possible. If the patient elects to combine therapy, closely monitor PT/INR.
Diabetic Agents/Insulin: Ginseng has been shown to have hypoglycemic effects. An interaction between Ginseng and antidiabetic agents has not been reported in the literature to date, but is theoretically possible based on the mechanism of action of Ginseng. |
Charles Barber
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 RxComms appeared to have been hired by Astrazeneca, who was preparing to release a drug to compete with warfarin. Witnesses for Astrazeneca later strongly denied any involvement before the British House of Commons.81 The practice of ghostwriting has been called no less than an ornate form of money laundering.82
As one would expect, there's good money to be had in ghostwriting. An article published in one of the top journals (e.g., The New England Journal of Medicine, The Lancet, The British Medical Journal) can net the "author" up to $20,ooo. |
Bottom Line Health
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| These foods are high in vitamin K, which can promote blood clotting and counteract the effects of blood thinners such as warfarin (Coumadin).
It's fine to eat small amounts—say, two or three weekly servings—of vitamin K-rich foods when taking an anticoagulant, but ask your doctor about eating more than that.
•Grapefruit. Both the juice and the whole fruit block liver enzymes that break down and clear drugs from the body. Eating grapefruit when you're on certain medications is like taking a higher dose, which can result in excessive levels of the drug in the blood. |
David Winston, RH(AHG), and Steven Maimes
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 John's wort with warfarin (Coumadin), digoxin, protease inhibitors, organ transplant antirejection drugs such as cyclosporin, or chemotherapy agents such as irinotecan. Use caution when taking this herb with contraceptive pills. Only use St. John's wort with antidepressants known as selective serotonin reuptake inhibitors (SSRIs) under a physician's supervision.
St. John's wort is available in a low-hyperforin extract that shows little, if any, ability to increase drug metabolism. |
Bottom Line Health
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| If the clot is caused by atrial fibrillation—the abnormal heartbeat that promotes clot formation—the preferred treatment is warfarin (Coumadin), a clot-preventing drug that is potent but difficult to manage.
If the clot did not originate in the heart, a patient's potential reaction to dipyrimadole must be considered, Sila says. Approximately one-third of the people who were put on combination therapy in the European trial stopped taking the medication because of side effects, most notably headaches.
In addition, the benefit of the combined therapy was apparent only after approximately 2. |
| The study was initially intended simply to show that self-monitoring in warfarin patients was safe, says study author Dr. Carl Heneghan, a clinical research fellow at Oxford University. Finding that it actually provided a substantial benefit came as something of a surprise.
"Each of the trials alone was not statistically significant, but combining them showed that you get a benefit in terms of mortality," he says. |
| EQUIPMENT
The method that patients use to self-monitor warfarin is basically the same as what diabetics do when they check their blood sugar levels—a drop of blood from a fingerstick is placed on a monitoring device. If the reading is outside the range set by the doctor, the patient can call him/ her for instructions about changing the dose.
Self monitoring offers a sense of freedom, not being tied to a clinic. |
David Winston, RH(AHG), and Steven Maimes
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| This herbal "drug" can interact with some medications, especially warfarin (Coumadin), so it only should be used under a doctor's supervision.
Acety-L-carnitine is a safe supplement that has neuroprotective effects. Various human and animal studies have shown conflicting results as to the benefits of this supplement in treating people with Alzheimer's disease and other age-related dementias. Some studies have indicated that it may have modest benefits, while in others it has failed to improve memory. |
Craig Pepin-Donat
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 As an example, taking vitamin E, which most people consider very safe, along with ginkgo biloba in combination with Coumadin, heparin, or warfarin (all prescription drugs to help thin the blood) increases the risk for subdural hematomas, retinal hemorrhages and internal bleeding.7 The combination of vascular dilation and blood thinning drugs can prove to be deadly.
Another supplement that has certain proven benefits that have been overexploited and exaggerated by the supplement industry is St. John's Wort. It has been used for centuries to relieve ulcers and nausea. Today, St. |
David W. Grotto, RD, LDN
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 Interaction between warfarin and mango fruit. Ann Pharmacother. 2002;36(5):940-941.
Percival SS, Talcott ST, Chin ST, Mallak AC, Lounds-Singleton A, Pettit-Moore J. Neoplastic transformation of BALB/3T3 cells and cell cycle of HL-60 cells are inhibited by mango (Mangifera indica L.) juice and mango juice extracts. / Nutr. 2006 May; 136 (5): 1300-1304.
Pott I, Marx M, Neidhart S, Muhlbauer W, Carle R. Quantitative determination of beta-carotene stereoisomers in fresh, dried, and solar-dried mangoes. / Agric Food Chem. 2003;51:4527-4531.
Van Duyn MAS, Pivonka E. |
Russell L. Blaylock, M.D.
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 In patients taking anticoagulants, such as warfarin, there is no evidence that vitamin E has a deleterious effect on clotting factors or bruising, which was determined in an extensive review of cardiac patients on warfarin who received either 100 mg or 400 mg a day of vitamin E.54'
Ascorbic Acid/Ascorbate Safety
One frequently cited complication associated with large-dose vitamin C supplementation is an increased risk of oxalate renal stones. There is not a single proven case of oxalate stone ever reported due to ascorbate consumption. |
Steven V. Joyal
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 Before trying curcumin, tell your doctor if you are taking any blood-thinning medications (such as warfarin, aspirin), if you are pregnant or breast-feeding, or if you have gallstones, an ulcer, or liver or bile obstruction. Side effects are rare.
DHEA
Dehydroepiandrosterone (DHEA), which is manufactured in the body and secreted by the adrenal glands, has been called the "mother of all hormones" because it serves as a precursor to both male and female sex hormones, such as testosterone and estrogen. |
Mike Adams
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| Here's an entry on warfarin found at Wikipedia:
Warfarin is used as a rodenticidefor controlling rats and mice in residential, industrial, and agricultural areas. It is both odorless and tasteless. It is effective when mixed with food bait, because the rodents will return to the bait and continue to feed over a period of days, until a lethal dose is accumulated (considered to be 1 mg/Kg/day over four to five days). It may also be mixed with talc and used as a tracking powder, which accumulates on the animal's skin andfur, and is subsequently consumed during grooming. |
| Here's a reasonable question to ask, then: If warfarin is deadly to rats, why is it supposedly good for humans?
Warfarin actually interferes with vitamin K metabolism. Vitamin K deficiency can then lead to risk of uncontrolled and massive bleeding, cartilage calcification and severe malformation of developing bone, as well as deposition of insoluble calcium salts in the arterial vessel walls (Linus Pauling Institute).
Recent research findings on dangerous drugs
Still skeptical? Here is just a fraction of the recent headlines and studies regarding the dangers of prescription drugs. |
David Winston, RH(AHG), and Steven Maimes
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| A recent study found no significant interaction between ginkgo and warfarin (Coumadin) in the usual dose levels. Still, it is a good idea to use caution if you are using ginkgo with such drugs and ask your doctor to schedule regular blood tests to be sure there is no interaction. Older reports claim that ginkgo has monoamine oxidase-inhibiting effects, but this information seems to be incorrect. In one study, ginkgo reduced anorgasmia in women taking antidepressant medications.
GOTU KOLA
Botanical Name: Centella asiatica Part Used: Herb
Gotu kola is known as kula kud in India. |
Joan Liebmann-Smith, Ph. D., and Jacqueline Nardi Egan
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 High on the list are the antituberculosis drug rifampin, the blood thinner warfarin, and some cancer drugs. These are many of the same medications that turn stools orange. (See Orange Stools, above.)
WARNING SIGN
Although you might think you're not getting dehydrated, by the time you're thirsty, you're already on your way. Dehydration can lead to seizures, brain damage, and even death. Dehydration is particularly dangerous in children and adults over 60. |
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