Kaayla T. Daniel, PhD, CCN
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 Sulfur is not a problem provided our levels of vitamin b6 are adequate. Pyridoxal-5-phosphate (the most active form of vitamin b6) is the coenzyme for cystathionine synthetase, the enzyme needed for proper conversion of sulfur-containing amino acids. It's in short supply in most American diets. The obvious solution is to optimize vitamin b6 levels, not to cut back on foods containing sulfur.
The fallacy of most other studies linking sulfur-rich animal foods to high calcium excretion is equally easy to find. |
Mehmet C. Oz., M.D. and Michael F. Roizen, M.D.
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 The Fine Print
Folic acid, vitamin b6, Yes Folic acid, vitamin B5, and vitamin B12 work by reducing levels vitamin BB of homocysteine, a body chemical that's related to increased risk of heart disease. You should get 800 micrograms of folate a day. Most folks get half of that in their diet, so add an additional 400-microgram supplement. Get 50 milligrams of vitamin b6 and 800 micrograms of B,2.
Coenzyme Q10 Yes Mitochondria convert glucose into electric energy, and one of the molecules carrying electrons in this process is coenzyme Q10. |
Bill Sardi
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 Thymidine deficiency has been reported to increase DNA replication errors and hence increase mutations (abnormal cells). A vitamin b6 deficiency occurring at the same time as contact with carcinogenic agents could well lead to tumor initiation and subsequent cancer development. [Medical Hypotheses 16: 421-28, 1985]
There are recent studies showing that deficiencies of vitamin b6 increase the risk for colon/rectal cancer [Journal National Cancer Institute 97: 684-92, 2005] The protective effect of B6 against colon cancer appears to be more prominent among young women who drink alcohol. |
Michael T. Murray
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 Also, diabetics should be sure to get at least 25 mg of vitamin b6 per day, as the level of vitamin b6 in body cells appear to be intricately linked to magnesium content. In other words, without vitamin b6 (as well as vitamin E), magnesium will not get inside the cell and will, therefore, be useless. zinc Zinc functions in more enzymatic reactions than any other mineral, as it is a cofactor in more than 200 different enzymes. |
| Individuals with long-standing diabetes or who are developing signs of peripheral nerve abnormalities should definitely supplement their diets with vitamin b6. vitamin b6 is also important in preventing other diabetic complications.
Vitamin Bg supplementation can be a very a safe and effective treatment for gestational diabetes (diabetes caused by pregnancy). In one study, fourteen women with gestational diabetes were given 100 mg of vitamin b6 each day for two weeks, which resulted in eliminating the diagnosis in twelve out of the fourteen women.32 magnesium ! |
Andreas Moritz
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 B-vitamins
Pyridoxine or vitamin b6 is a combination of six substances. Since most parts of this vitamin occur in bound form, analytic methods fail to determine how much of it is contained in food. It is also not possible to make any reliable statements about how much of it we require. Still the nutritional textbooks suggest a 1-2 u.g daily intake, which is pure guesswork. What is known, though, are its side effects.
Vitamin B6 is often used as a drug. Its use is indicated for depression, premenstrual tension, schizophrenia, and child asthma. |
Ruth Winter, M.S.
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 PYRIDOXINE DILAURATE See vitamin b6.
PYRIDOXINE DIOCTENOATE vitamin b6 Hydrochloride. Texturizer. A colorless, or white, crystalline powder present in many foodstuffs. A coenzyme that helps in the metabolism of amino acids (see) and fats. Also soothing to skin. Nontoxic.
PYRIDOXINE DIPALMITATE See vitamin b6. PYRIDOXINE HCL See vitamin b6.
PYRIDOXINE TRIPALM1TATE vitamin b6 Tripalmitate. See Pyridoxine HCL.
PYRITHIONE ZINC Head and Shoulders Antidandruff Shampoo. X-Seb Shampoo. Zincon Dandruff Shampoo. |
Hyla Cass, M.D.
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 Needed supplements: Take calcium (1,000 mg), folic acid (400 meg), vitamin b6 (10-25 mg), magnesium (500-600 mg), zinc (25 mg), and CoQ10 (100-300 mg).
Calcium Channel Blockers: amlodipine (Norvasc), diltiazem
(Cardizem), felodipine (Plendil), idradipine (DynaCirc), nicardipine (Cardene), nisoldipine (Sular), and verapamil (Calan, Covera HS, Isoptin, Veralam)
This drug class reduces blood pressure through a different mechanism than the diuretics.
Actions: These drugs reduce the heart's pumping force and dilate arteries. |
Ray D. Strand
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 The fact remains these women need higher amounts of folic acid, vitamin b6, and vitamin B12.
Boron
Boron is an interesting nutrient when it comes to bone metabolism. When study subjects took boron in supplementation, the urinary excretion of calcium decreased by approximately 40 percent. Boron also increases magnesium concentrations and decreases phosphorous levels.15 Supplementation with 3 mg daily of boron is more than adequate.
Silicon
Silicon is important because of its ability to strengthen the connective tissue matrix, which strengthens bone. |
| Definitely be careful when using higher doses of vitamin b6.
Folic Acid
Folic-acid supplementation may mask an underlying vitamin B12 deficiency. Therefore, people should always take vitamin B12 supplements in tandem with folic acid. However, there has not been reported any serious problems of taking folic acid even up to 5 grams per day. This is another reason that cellular nutrition is a safe way to supplement your diet.
Choline
Choline is generally well tolerated, although at very high doses (20 g per day), it can create a fishy odor and cause some nausea, diarrhea, and abdominal pain. |
| There is not nearly as much money to be made in the sale of vitamin B12, vitamin b6, and folic acid. Sad to say, we are caught in the ripple effects of the economics of medicine. Could this possibly have been the underlying reason that Dr. Kilmer McCully lost his research funds and his job at Harvard?
Dr. McCully takes his own follow-the-money approach, asking who stands the most to gain by not educating people about the dangers of homocysteine. "The most dramatic improvements in longevity over the last couple of hundred years have been through public health, not through medicine," he says. |
Hyla Cass, M.D.
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| There is substantial evidence that higher-dose B6 could be helpful for treatment of diabetic nerve damage (neuropathy); vitamin b6 inhibits the formation of glycosylated proteins, which damage nerves in diabetes. B6 may help to prevent diabetic eye damage. It is also effective for premenstrual syndrome (PMS) and pregnancy-induced morning sickness; other research shows that higher-dose B6 could be helpful for people who are depressed or who have carpal tunnel syndrome.
You and your doctor may agree to try a higher dose of B6 if there's the potential for benefit. |
| Dose: Folic acid (400 meg), vitamin B12 (200-1,000 meg), vitamin b6 (10-25 mg).
OTHER SUPPLEMENTS FOR BETTER BLOOD-SUGAR CONTROL
People with diabetes can benefit from the comprehensive support a multivitamin. Diabetics are less able to fight off infections than non-diabetics. It seems that a multivitamin can boost diabetics' immunity and resistance to infection. In one revealing study, only 17 percent of diabetics who took multivitamins reported having an infectionsuch as a cold, the flu, or a stomach fluwhile 93 percent who took a placebo (dummy) pill did report having one. |
Ray D. Strand
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| The nutrients needed for the body to make its own most effective, natural defense are selenium, vitamin b6, N-acetyl-L-cysteine, and niacin.
As you learn more about cellular nutrition, you will begin to realize the importance of providing all of these precursor nutrients to the cell. In this case alpha-lipoic acid and vitamin C are also critical because they both have the ability to regenerate glutathione. Since it is difficult to increase the levels of glutathione within the cell, these nutrients should also be present in supplementation so that the glutathione can be used again and again. |
Hyla Cass, M.D.
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| Take daily in divided doses, best with breakfast and dinner, one-half dose each time:
Alpha-lipoic acid: 200-600 mg
Chromium: 200 meg
Coenzyme Q10: 30-200 mg
Folic acid: 400 meg
Magnesium: 500-600 mg
Mixed antioxidant supplement
Vitamin 320 mg (as benfotiamine)
Vitamin B6: 10-25 mg
Vitamin B]2: 200 meg
Vanadium: 2 mg
Anyone with diabetes needs to take extra-good care of his or her heart. |
Jonny Bowden, Ph.D., C.N.S.
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 Also loaded with fiber and vitamins and minerals, in particular magnesium and vitamin b6 (two nutrients that many are people deficient in). Also an excellent source of vitamin E. cell membranes. Also, eggs contain lutein, a nutrient that protects the eyes. And in one Chinese study, six eggs a week lowered the risk of breast cancer by 44 percent. I have seen eggs worsen the symptoms of gallbladder disease, though; eggs should be avoided in those patients.
5. Oatmeal: One of the healthiest carbohydrates. |
Hyla Cass, M.D.
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| Needed supplements:
Folic acid: Supplementing with up to 1 gram (800 meg) of folic acid daily should help prevent folic acid deficiency.
Vitamin B6: 50 mg daily.
Vitamin Bi2: 1,000 meg daily.
Certainly, we're all grateful for medicines when we really need them, despite the reality of risks and side effects. A powerful plan to replenish nutrients known to be depleted by those drugs, combined with the use of other nutrients scientifically shown to be helpful for your condition, can give you even greater control of your path back to health. |
| Nutrients depleted: These medicines can deplete CoQ10 and vitamin
Needed supplements: Take 100-300 mg of CoQ10 and 10-25 mg of vitamin b6.
NATURAL REMEDIES FOR HYPERTENSION
Some natural remedies work to take blood pressure down a few notches into safe territory.
Diet is a big one here! Stick with the plan I've described in this book, and your blood pressure, cholesterol, and weight are going to come down. The DASH (Dietary Approaches to Stop Hypertension) diet, which is commonly recommended by mainstream docs, will work too, but in my opinion it overemphasizes grains. |
Jack Challem
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 Avoid taking any supplements with vitamin b6 later than midafternoon because large amounts of this vitamin can stimulate vivid dreams.
These supplements might help you sleep better.
Melatonin, 250 meg to 9 mg daily. This hormone, which you can buy without a prescription at most health food stores and pharmacies, regulates your sleep cycle. The time that you take it, however, and the dosage are critical. If you take too much or take it at the wrong time of day, it will leave you feeling groggy. Start with about 250 meg, about two hours before bedtime. |
Herbert Ross, DC with Keri Brenner, L.Ac.
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 The body requires vitamin b6 to convert the amino acid tryptophan into the neurotransmitter serotonin, which helps control sleep. Deficiencies occur as a result of eating a diet high in fats and low in fruits and vegetables.
Food sources: Brewer's yeast, whole grains, legumes, nuts, and seeds.
Supplements: There are two forms of B6, pyridoxine hydrochloride and pyridoxal-5-phosphate (the most active form). For efficient absorption of pyridoxine by the body, sufficient levels of riboflavin and magnesium should be present. |
| Higher dosages (over 100 mg) could cause some side effects, including mild nausea. vitamin b6 should be taken on the same day as 5-HTP, because it is necessary for converting 5-HTP into serotonin.
Other amino acids may play a role in sleep disorders, depending on the person and their nutritional status. Jonathan Wright, MD, a pioneer in nutritional medicine, has had success in treating insomnia using supplements of essential amino acids. He reports the case of a man who had been suffering from insomnia most of his adult life. |
Tori Hudson, N.D.
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 Some of these have shown no effect from vitamin b6, but most of the studies have shown that there was a substantial and broad effect on the whole range of PMS symptoms. An overview of these studies has been published in the British Journal of Obstetrics and Gynaecology ?A The studies have used anywhere from 50 to 500 mg per day.
Vitamin Bs is thought to be unique in its ability to increase the synthesis of several neurotransmitters in the brain. These neurotransmitters include serotonin, dopamine, norepinephrine, epinephrine, taurine, and histamine. |
Herbert Ross, DC with Keri Brenner, L.Ac.
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| In the absence of adequate vitamin b6, the body cannot convert L-tryptophan into melatonin. Deficiencies in folic acid (also known as folacin or folate), another member of the B vitamin family, have been linked to insomnia and restless legs syndrome.16
Vitamin E deficiency may be a factor in restless legs syndrome.17
People suffering from insomnia may be deficient in the mineral zinc, particularly infants with frequent nighttime waking and crying.
Deficiencies in copper and iron have been linked to greater difficulties in getting to sleep and decreased quality of sleep. |
Dr. Steve Blake
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 Some amino acids get to the TCA cycle directly using vitamin b6 (PLP). The TCA cycle uses oxygen to produce energy aerobically. Niacin (NAD), thiamin (TPP), and riboflavin (FAD) are needed to keep the cycle running. Thiamin (THF) and vitamin B12 are used to boost other compounds into the TCA cycle.
Adenosine triphosphate (ATP) is the fully charged energy battery of the cell.
STEP 4, PUMPING UP ATP
The fourth step is called the electron transport chain. The electron transport chain pumps up the energy battery of the body, which is known as adenosine triphosphate (ATP). |
Neal D. Barnard and Bryanna Clark Grogan
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 You will find plenty of folic acid and vitamin b6 in beans, vegetables, and fruits; plant-based food sources of B12 are limited to supplemented products such as fortified soy milk and cereals (e.g., Total, Product 19, and Kellogg's Corn Flakes), nutritional yeast, and a few other foods.
In addition to having plenty of fruits and vegetables in your diet every day, the following is a sensible regimen.
1. A multivitamin each morning. This will provide adequate folic acid, vitamin b6, and vitamin B12. |
Dr. Steven R. Gundry
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 Typical daily dose: 500-1,000 mg
Folic Acid and Other B Vitamins Mixed B vitamins include thiamin, riboflavin, niacin, vitamin b6 (pyridoxine hydrochloride), vitamin Bi2 (cyano-cobalamin), biotin, and pantothenic acid. Along with folic acid, they were among the first the government required in "enriched white flour. |
| A word of warning: More than 300-500 mg of vitamin b6 (pyridoxine) can cause severe neurologic problems.
Typical daily doses: folic acid: 800-5,000 meg; B vitamins: 50-100 meg or mg (sold as B-50 orB-ioos, which have 50 or 100 meg and/or mg of each of the B vitamins above)
If You MuAt Cheat
11 I I 1 111 I
As you have heard me say, do what you can, with what you have, when you can, wherever you are. It's better not to get hung up on the small stuff, when the big stuff is what really counts. If an occasional departure will keep you on the program, go for it. |
Ben-Erik van Wyk
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 Nuts, vegetables and unrefined cereals (as well as meat) are good sources of vitamin b6, so that deficiencies are extremely rare. The most common compound is pyridoxine, with a RDA of 2 mg.
Vitamin B12
The chemical name for this vitamin is cobalamin. It is not present in plant foods but occurs in animal foods and yeast products. A deficiency of vitamin B]2 may lead to inadequate absorption of folic acid.
OH OH OH OH
I I I I H2CCH-CH-CH-CH2
Vitamin B6 (Pyridoxine) Chemical structures of important B vitamins
Biotin (vitamin H)
Biotin seldom causes deficiency symptoms. |
Mike Adams
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 As examples of how easily vitamin b6 is lost in the processing of food, raw sugar cane has a good amount, while refined sugar has none; whole wheat flour contains nearly 0.5 mg. of pyridoxine (wheat germ and wheat flakes have much more), while refined wheat flour has almost none, and even whole wheat bread has lost nearly all of its vitamin b6. Much of the chromium in whole grains and sugarcane is lost in making refined flour (40 percent loss) and white sugar (93 percent loss). In addition, there is some evidence that refined flour and sugar deplete even more chromium from the body. |
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