Dr. Steven R. Gundry
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 But don't rush out to the health food store to buy resveratrol capsules, which are generally worthless because resveratrol is inactivated by exposure to oxygen. The fermentation process that produces wine yields carbon dioxide, which protects the resveratrol from the effects of oxygen. Interestingly, the higher the altitude at which grapes are grown, the more resveratrol they produce to protect against sun damage. In Sardinia, where grapes grow at 4,000 feet above sea level, there are more centenarians per 100,000 people than almost any other culture. |
| Red grapes produce a phytochemical called resveratrol, which protects them from ultraviolet radiation, fungus infections, and other stressors. resveratrol activates anti-aging genes that stimulate the production of proteins that circulate in your body, throwing overboard cells that aren't pulling their weight and rejuvenating cells damaged by advanced glycation end-products (AGEs). But don't rush out to the health food store to buy resveratrol capsules, which are generally worthless because resveratrol is inactivated by exposure to oxygen. |
Gabriel Cousens
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 Anti-Aging: Caloric Restriction and Resveratrol
To further make the point of the main theoretical principle of the Tree of Life 21-Day+ Program, Life Extension 2004 reports that a phytonu-trient, resveratrol, has been found by Harvard medical school researchers to activate a longevity gene in yeast that extends life by 70 percent. In an interview, leading resveratrol researcher Dr. |
by Michael Murray, N.D. and Joseph Pizzorno, N.D.
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| Resveratrol has been identified in more than seventy species of plants, including mulberries and peanuts, but the flesh of grapes is an especially good source. resveratrol acts as an antioxidant and has also been shown to reduce the buildup of plaque in arteries. In addition to possibly reducing the risk for atherosclerosis, animal studies demonstrate some anticancer effects and antiinflammatory action. Fresh grape skin contains about 5 to 10 milligrams of resveratrol per serving, while red wine concentrations range from 1.5 to 3 milligrams per liter. |
Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D.
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 An 8-ounce glass of red wine provides approximately 640 meg of resveratrol, while a handful of peanuts provides about 73 meg of resveratrol. resveratrol supplements (often found in combination with grape extracts or other antioxidants [page 467]) are generally taken in the amount of 200-600 meg per day. This is far less than the amount used in animal studies to prevent cancer (page 87): equivalent to more than 500 mg (500,000 meg) per day for an average-sized human. Therefore, one should not assume that the small amounts found in supplements or food would necessarily be protective. |
Dr. Steven R. Gundry
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| The fermentation process that produces wine yields carbon dioxide, which protects the resveratrol from the effects of oxygen. Interestingly, the higher the altitude at which grapes are grown, the more resveratrol they produce to protect against sun damage. In Sardinia, where grapes grow at 4,000 feet above sea level, there are more centenarians per 100,000 people than almost any other culture. As I like to say, if you drink red wine, you'll be fine!
COFFEE,TEA-OR CHOCOLATE?
Whether or not you enjoy a glass of wine with dinner, I suspect you do like chocolate. |
by Michael Murray, N.D. and Joseph Pizzorno, N.D.
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| Resveratrol belongs to a group of compounds called phytoalexins that plants produce in self-defense against environmental stressors, such as adverse weather or attack by insects or microorganisms. resveratrol has been identified in more than seventy species of plants, including mulberries and peanuts, but the flesh of grapes is an especially good source. resveratrol acts as an antioxidant and has also been shown to reduce the buildup of plaque in arteries. |
Lester A. Mitscher and Victoria Toews
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 Of late, considerable attention has been devoted by scientists to the antioxidant properties of red wine's phenolic constituent, resveratrol, as an important contributor. White wine contains much less of this antioxidant, and therefore it has fewer health benefits. resveratrol, unfortunately is not in green tea. However, green tea may offer even greater potential for health protection, since it not only includes the flavonoids active in red wine but also includes even more powerfully protective flavonoids that are unique to it.
When Michael G. Hertog, Ph.D. |
Peter J. Whitehouse and Daniel George
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 Red wines are fermented with grape skins, allowing the wine to absorb greater amounts of resveratrol than white wines, which are fermented without grape skins. Thus, some nutritionists are recommending a little red for the head.
The precise amount of wine needed to reap any possible benefits of resveratrol is unknown and will vary depending on your size and weight. As a general rule, you should try to limit yourself to no more than two glasses a night. Recent studies have linked moderate intake of alcohol with a 45 percent less risk of developing dementia. |
Gabriel Cousens
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| Xi Zhao-Wilson told Life Extension: "There has been a great deal of attention focused on resveratrol in the past few years, following a study showing that resveratrol activates molecular pathways involved in life-span extension, now demonstrated in yeast, worms, flies, fish, and mice, and which possibly bear a relationship to mechanisms underlying caloric restriction."8 The tremendous amount of scientific evidence of the effect of caloric restriction on upgrading our gene expression supports the link of caloric restriction and longevity. |
Mehmet C. Oz., M.D. and Michael F. Roizen, M.D.
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 One of the ways to activate sirtuin is through resveratrol, found in red wine. You get the health benefits of wine-lower LDL, more antioxidants—if the skin of the grape touches the seeds for at least three weeks. But in many of today's wines, that time is less than a week. Another factor: The smaller the grape and the more seeds it has, and the cooler the climate it grows in, the better. Knotweed (a Japanese plant) has forty times more resveratrol per pound than grapes do, and it grows everywhere (and makes a great apple pie). |
Peter J. Whitehouse and Daniel George
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| The skin of red grapes contains a compound called resveratrol, which has recently come into vogue. Several studies have shown that this polyphenic compound increases levels of an enzyme—heme oxygenase?that has antioxidant and anti-inflammatory properties and may protect against neuronal cell dysfunction. Red wines are fermented with grape skins, allowing the wine to absorb greater amounts of resveratrol than white wines, which are fermented without grape skins. Thus, some nutritionists are recommending a little red for the head. |
Gabriel Cousens, M.D.
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 Red wine also has a number of phenolics, the most important being resveratrol and quercetin, which alter gene expression and enhance phenotypic expression to protect against blood clot formation as in heart disease. resveratrol also has certain anti-aging qualities that are recently being touted to mimic the calorie restriction effect. However, red wine also has the downside of being alcohol. Alcohol does many things to disregulate and undermine healthy gene expression, particularly in the neurotransmitter systems, as well as other systems in the body. |
Jonny Bowden, Ph.D., C.N.S.
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 So red wine is antioxidant rich, loaded with healthy polyphenols, and a major dietary source of the anticancer, antiaging compound resveratrol. On the other hand, wine—and alcohol in general—is one of those substances where God truly is in the details, and the dosage makes the poison. Moderate intake of red wine: good. Too much alcohol, especially for those with addictive personalities: unmitigated disaster. Alcohol can raise triglycerides, increase blood pressure, and lead to weight gain. And it's not possible to predict in which people alcohol will lead to alcoholism. |
Mehmet C. Oz., M.D. and Michael F. Roizen, M.D.
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| For example, just ten minutes of walking turns on a gene that decreases the rate of cancer growth, and resveratrol (the ingredient found in red wine) turns on a gene that slows or stops a dangerous inflammatory process that happens inside your body. And in the very near future, we're going to be able to develop medicines tailored to individuals whose genes work differently from others'.
Because each of us has a unique genetic fingerprint, the detection, prevention, and treatment of diseases can be difficult. |
Mike Adams, the Health Ranger
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 Coenzyme Q10 is also present at 25mg per serving, and LivingFuel Rx Super Greens even delivers grape seed, skin and stem extracts containing resveratrol (which are outstanding for heart health).
The extra enzymes and probiotics enhance the digestibility and bioavailability of the nutrients found in LivingFuel Rx Super Greens.
LivingFuel Rx Super Greens is suitable for vegetarians or people with gluten sensitivities. It contains no animal products and no wheat. |
Gabriel Cousens, M.D.
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| Polyphenols are broken down to subclasses such as flavonoids and proanthocyanidins. resveratrol is found in organic grapes, pine trees, and other plants such as polygonnum cuspidatum. This expansion of information on resveratrol helps to make the point of the role of phytonutrients in gene control and as antioxidants. When we cook our food, many of the actions of these phytonutrients are compromised or entirely lost. The effects of free radical damage are seen throughout the whole body. |
Tori Hudson, N.D.
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 These cardioprotective phenols included flavonoids, resveratrol, and curcumin. A daily 25 ml dose of any type of olive oil has been shown to reduce lipid cardiovascular risk factors56 by decreasing oxidative damage on lipids, increasing HDL cholesterol levels, and improving the glutathione balance that protects against oxidative stress.
Hydrogenated oils (an unsaturated oil that has been made into a saturated fat) should be avoided for cardiovascular health. Hydrogenated oil raises LDL, lowers the protective effects of HDL, and can in fact increase the incidence of heart disease. |
Jonny Bowden, Ph.D., C.N.S.
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| Just about every antioxidant that's in wine can be gotten from fruits and vegetables, and even resveratrol is plentiful in dark grapes and boiled peanuts.
Tea
*
(green, black, and white)
After water, tea is probably the most consumed beverage in the world. Not counting water, it's also probably the healthiest.
The key to the health benefits of tea can be found in a large group of protective plant-based chemicals generally known as phenolic compounds, or polyphenols.
First, some clarifications. |
Erich Grotewold
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 In a recent study in mammals, quercetin, genistein, and resveratrol increased PTEN lipid phosphatase activity but not protein phosphatase activity (Waite et al, 2005), suggesting that flavonoids may be more likely to affect AtPTEN lipophosphatase activity in planta.
Studies in animal cell lines have shown that flavonoids alter multiple kinase and phosphatase activities (reviewed in Williams et al., 2004). Apigenin inhibits protein kinase C (PKC) and MAPK (Kuo and Yang, 1995; Huang et al., 1996). |
Ralph Moss, PhD
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 This is most likely due to the presence of an intriguing substance called resveratrol. resveratrol is an antioxidant found in many foods, but most abundandy in peanuts and red grapes.
Red wine from cold climates (such as France) is a particularly good source of resveratrol. It is less concentrated in red wines from warmer climes such as California, Italy, Spain, or Portugal.
Studies from the University of Illinois have shown that the number of early breast lesions and skin cancers in mice dropped dramatically when they were given high doses of resveratrol. |
Gabriel Cousens, M.D.
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| Red wine also has a number of phenolics, the most important being resveratrol and quercetin, which alter gene expression and enhance phenotypic expression to protect against blood clot formation as in heart disease. resveratrol also has certain anti-aging qualities that are recently being touted to mimic the calorie restriction effect. However, red wine also has the downside of being alcohol. Alcohol does many things to disregulate and undermine healthy gene expression, particularly in the neurotransmitter systems, as well as other systems in the body. |
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