Tori Hudson, N.D.
See book keywords and concepts |
 Quercetin and other bioflavonoids also contribute in other ways to mitigate the inflammatory process. quercetin may be beneficial to connective tissue by limiting inflammation and associated tissue degradation, improving circulation, and promoting a strong collagen matrix.60-61 quercetin also plays a part in modulation of the inflammatory response, at least in part by modulating prostaglandin synthesis and cytokine production.62
Quercetin
500-1,000 mg twice daily Bioflavonoids
500-1,000 mg twice daily
Oregon Grape Root {BerberisAquifolium). |
Mike Adams, the Health Ranger
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 It does not get into the body very well. quercetin chalcone was developed by Thorne Research and it immediately gets into the body. It is water-soluble.
We also use quercetin chalcone, both in our Joint Health Formula for Pets and in our human Joint Health Formula. We wanted a powerful anti-inflammatory for joints. quercetin chalcone, as well as turmeric, are just phenomenal for joint problems. Then we have the grape seed extract in there. So we put quercetin chalcone in Pet-C Plus because it was a more recent design than Pro-C, and that makes this formula even more potent. |
Gabriel Cousens
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 One popular flavonoid is quercetin. Found in apples, onions, and garlic, quercetin helps improve gene expression related to allergy and arthritis, and helps maintain the integrity of vascular tissue for improved circulation. Bioflavonoids, of which quercetin is one, are among the most important modifiers of gene expression, in addition to being antioxidants.
Once we understand this first principle about eating a Culture of Life anti-diabetogenic diet, we start to understand that what we take into our body has very important healing effects. In a October 1997 article in Science by Dr. |
Tori Hudson, N.D.
See book keywords and concepts |
| Quercetin may be beneficial to connective tissue by limiting inflammation and associated tissue degradation, improving circulation, and promoting a strong collagen matrix.60-61 quercetin also plays a part in modulation of the inflammatory response, at least in part by modulating prostaglandin synthesis and cytokine production.62
Quercetin
500-1,000 mg twice daily Bioflavonoids
500-1,000 mg twice daily
Oregon Grape Root {BerberisAquifolium). |
Mike Adams, the Health Ranger
See article keywords and concepts |
| We also use quercetin chalcone, both in our Joint Health Formula for Pets and in our human Joint Health Formula. We wanted a powerful anti-inflammatory for joints. quercetin chalcone, as well as turmeric, are just phenomenal for joint problems. Then we have the grape seed extract in there. So we put quercetin chalcone in Pet-C Plus because it was a more recent design than Pro-C, and that makes this formula even more potent.
Back to the issue of vitamin C with an animal -- any animal that has an illness is going to need more vitamin C. |
Brenda Watson and Leonard Smith
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 In this group of phenolics, a large family of chemicals that includes the flavonoids, is a natural antioxidant called quercetin that protects apples against disease. Research at Cornell University shows that consuming quercetin (which is mostly contained in apple skin and just below the peel) may lower the risk of Alzheimer's and Parkinson's disease by defending nerve cells against free radical damage. In addition, previous studies have shown that quercetin helps the body fight off cancer. Is this proof that an apple a day keeps the doctor away? |
Joe Graedon, M.S. and Teresa Graedon, Ph.D.
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 Quercetin and Bromelain
Two other natural products that may be worth consideration against allergies are quercetin and bromelain. quercetin is an antioxidant flavonoid that is found in many fruits, vegetables, and herbs. The anti-inflammatory effect of quercetin helps stabilize mast cells. These are the cells in your eyes, nose, and lungs (and other places in your body) that are highly sensitive to allergens.
Think of mast cells as floating mines. |
Mike Adams, the Health Ranger
See article keywords and concepts |
| We wanted a powerful anti-inflammatory for joints. quercetin chalcone, as well as turmeric, are just phenomenal for joint problems. Then we have the grape seed extract in there. So we put quercetin chalcone in Pet-C Plus because it was a more recent design than Pro-C, and that makes this formula even more potent.
Back to the issue of vitamin C with an animal -- any animal that has an illness is going to need more vitamin C. These other factors in there are going to strengthen their bodies and trap free radicals and detoxify. |
Elaine Magee
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 Apples offer a powerful assortment of phytochemicals, including quercetin, catechin, phloridzin, and chlorogenic acid. Procyaniclins, also found in high concentrations in red wine, grapes, cocoa, and cranberries, are thought to have a protective effect on the vascular system. quercetin, also found in onions, red wine, broccoli, tea, and ginkgo biloba, appears to influence some carcinogenic markers.
Savor the skins! |
Byron J. Richards, CCN
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 The bioflavonoid quercetin, found in fresh vine-ripened fruit and available as a nutritional supplement, induces death in breast-cancer cells.832 quercetin demonstrated the ability to prevent environmental chemicals from promoting estrogen driven breast cancer.833
Interestingly, quercetin is shown to be more effective than Tamoxifen at binding to type II EBS receptors. The same study also shows it to be very effective at stopping the progression of a human breast-cancer cell line. |
Patrick Holford
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 Because strawberries, as well as other berries, are especially high in a quirky bioflavonoid called quercetin. quercetin, along with other bioflavonoids in berries, can also improve the health of capillaries and connective tissues. Because of this, the many benefits of quercetin include alleviating bruising, edema, varicose veins, and fragile capillaries.
A major benefit of quercetin is its ability to inhibit the release of histamine. |
Gabriel Cousens
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| Flavonoids include quercetin, which promotes insulin secretion and is a potent inhibitor of sorbitol accumulation. quercetin has been found in vitro to inhibit sorbitol accumulation in human lenses,121 and has been found to slow the course of cataract formation.122'123 Other flavonoids include naringin and hespertin; both have been found to be aldose reductase inhibitors, therefore protecting against the accumulation of sorbitol. |
Mike Adams, the Health Ranger
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| We put other nutrients in Joint Health Formula that act much more quickly, like tumeric and quercetin chalcone.
If you have inflammation, you have pain. The turmeric and quercetin chalcone will knock it down so fast that suddenly -- and I know this because sometimes when I overdo it in yoga or during exercise, and I have pain and I take this stuff -- the pain goes away. If I forget to take it, pow! Within half a day, it is back again. |
Brenda Watson and Leonard Smith
See book keywords and concepts |
| Research at Cornell University shows that consuming quercetin (which is mostly contained in apple skin and just below the peel) may lower the risk of Alzheimer's and Parkinson's disease by defending nerve cells against free radical damage. In addition, previous studies have shown that quercetin helps the body fight off cancer. Is this proof that an apple a day keeps the doctor away? I think we're just beginning to understand the power of these phytochemicals and there will be nothing but good news ahead. |
Gabriel Cousens
See book keywords and concepts |
| Found in apples, onions, and garlic, quercetin helps improve gene expression related to allergy and arthritis, and helps maintain the integrity of vascular tissue for improved circulation. Bioflavonoids, of which quercetin is one, are among the most important modifiers of gene expression, in addition to being antioxidants.
Once we understand this first principle about eating a Culture of Life anti-diabetogenic diet, we start to understand that what we take into our body has very important healing effects. In a October 1997 article in Science by Dr. |
Gabriel Cousens, M.D.
See book keywords and concepts |
 A very popular flavonoid is called quercetin. Found in apples, onion, and garlic, quercetin helps improve gene expression in relationship to allergy and arthritis.52 Bioflavonoids, of which quercetin is one, are perhaps some of the most important modifiers of gene expression, in addition to being antioxidants.
This discussion takes us into the whole question of the use of wine and black and Chinese green teas, which are very high in bioflavonoids. The Chinese green teas also contain the class of bioflavonoids called cate-chins. These catechins are particularly strong antioxidants. |
Tori Hudson, N.D.
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| Over 4,000 different flavonoids have been identified in foods and plants. quercetin, rutin, catechin, and hesperidin are the most frequently used in medicine. Flavonoids inhibit the peroxidation of lipids by acting as free radical scavengers.284 quercetin specifically has been shown to inhibit LDL oxidation.285 In addition to these direct antioxidant effects, flavonoids inhibit platelet aggregation, protect vitamin E from oxidation, and chelate iron. In numerous dietary studies, flavonoids have been shown to reduce cardiovascular disease. |
Gabriel Cousens
See book keywords and concepts |
| Flavonoids include quercetin, which promotes insulin secretion and is a potent inhibitor of sorbitol accumulation. quercetin has been found in vitro to inhibit sorbitol accumulation in human lenses,121 and has been found to slow the course of cataract formation.122'123 Other flavonoids include naringin and hespertin; both have been found to be aldose reductase inhibitors, therefore protecting against the accumulation of sorbitol. |
Joerg Gruenwald, Ph.D.
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 Other Names: Yellow Willowherb
ACTIONS AND PHARMACOLOGY
COMPOUNDS
Flavonoids: glycosides of the myricetin, kaempferol and quercetin, including among others rutin
The constituents of the drug have not been extensively investigated.
EFFECTS
Loosestrife has an astringent effect. The main active principle is rutin.
INDICATIONS AND USAGE
Loosestrife is used for scurvy, diarrhea and dysentery as well as hemorrhages (nose bleeds and heavy menstrual blood flow) and wounds. |
Bill Sardi
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 This simple emulsifier has been shown to improve the biological action of natural herbal products such as quercetin, ginkgo biloba and silybin, the active ingredient in milk thistle. [Planta Medica 67: 326-30, 2001; European Journal Cancer 39: 2403-10, 2003; Bioscience Biotechnology Biochemistry 67: 2548-55, 2003]
Anemia: Erythropoietin
Iron deficiency anemia resulting in low red blood cell count is common among cancer patients. Cancer activates inflammatory molecules that destroy red blood cells. |
| Surgery 78: 608-12, 1975]
Two nutritional supplements that can be acquired in stores, quercetin and rutin, have been shown to inhibit formation of pre-cancerous changes in the colon regardless of the fat content of the diet. [Nutrition & Cancer 20: 199-204, 1993]
Selenium and folic acid also prevent intestinal polyps. [Medical Tribune, April 8, 1993; Journal Nutritional Biochemistry 5: 170-75, 1994]
Individuals taking vitamin A, C and E supplements experience a lower rate of intestinal polyps. |
| The combination of curcumin (480 mg) and quercetin (20 mg) given to patients with familial adenomatous polyposis 3 times a day reduced the number and size of polyps by 50-60% with minimal side effects. The effect was equivalent to that achieved by nonsteroidal anti-inflammatory agents without the drawback of bleeding gastric ulcers or adverse cardiovascular events. [Clinical Gastroenterology Hepatology, June 4, 2006 online]
There is also considerable evidence for a protective effect of estrogens against colorectal cancer incidence. |
| Biomed Pharmacotherapy 59: 56-60, 2005] quercetin has similar properties to Cimetidine.
Flaxseed lignans, which have similar properties to soy, have also been shown to protect against colon cancer. [Carcinogenesis 17: 1343-48, 1996; Journal Nutrition 135: 598-602, 2005] One study found that when animals were switched from corn oil to flaxseed oil diets the incidence of tumors was reduced from 100% to 54% [Nutrition Cancer 51:52-58, 2005]
Lesser known risk factors for colon cancer
There are a number of lesser known risk factors and preventive measures for colon cancer. |
| The body will create defenses (P-glycoprotein, cytochrome p450 enzymes) against toxic drugs over time. quercetin and resveratrol inhibit drug resistance and may be compatible with prescribed chemotherapy. These natural agents will enhance the effect of toxic drugs and therefore caution is advised. [Federation of European Biochemical Societies Journal 272: 4725-40, 2005]
Prevent side effects caused by chemo or radiation therapy
Various tissues in the body are at increased risk for damage while undergoing chemotherapy or radiation. Protection with antioxidants and other nutrients is advised. |
| Acta Haematologica 84:139-43, 1990]
Resveratrol and quercetin inhibit cancer cells from adhering and creating new colonies. |
Byron J. Richards, CCN
See book keywords and concepts |
| Interestingly, quercetin is shown to be more effective than Tamoxifen at binding to type II EBS receptors. The same study also shows it to be very effective at stopping the progression of a human breast-cancer cell line.834 There is data to support the use of quercetin and Tamoxifen together, helping to synergistically make cancer more susceptible to medical treatment.835
Indole-3-caribinol (I3C) is the active component of cruciferous vegetables, mentioned in the chapter on prostate cancer. |
Marshall Editions
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 Antihistamines: To treat sneezing due to allergies, take an antihistamine such as Benadryl™ at bedtime and Claritin™ during the day to suppress the sneezing. quercetin is a natural supplement that also treats sneezing caused by allergies; take 1 g twice a day.
TRADITIONAL CHINESE MEDICINE
Herbs: If sneezing persists, try some tea formulas that are convenient and effective for reducing this condition. If you have an allergic reaction to any herb, stop drinking the tea. |
| Supplements: Take 1,000 mg of quercetin (eucalyptus flavonoid) three times a day. Take 500 mg-1 g of vitamin C a day, and add zinc and vitamins A and E to your diet. Take 4 g of EPA DHA (an omega-3 fat) fish oil a day in a 3:2 ratio.
Medication: Topical nasal steroids such as Flonase®, oral antihistamines, topical azelastine, or cromolyn sodium in combination with mucolytics (guaifenesin) and decongestants are usually prescribed. Although they do mask symptoms, they do not alleviate the actual cause. |
Joerg Gruenwald, Ph.D.
See book keywords and concepts |
| ACTION AND PHARMACOLOGY
COMPOUNDS
Saponins
Nitrite glycosides: menisdaurin, not cyanogenic
Flavonoids: including, among others, rutin, kaempferol and quercetin glycosides
Caffeic acid derivatives: chlorogenic acid Sterols: beta-sitosterol, stigmasterol
Triterpenes: alpha-amyrin, alpha-amyrinester, beta-amyrin, ursolic acid
Purine alkaloids: only traces of theobromine
EFFECTS
No information is available.
INDICATIONS AND USAGE
Holly is used as a diuretic. Also used for coughs, digestive disorders and jaundice. |
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