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Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements Phyllis A. Balch, CNC See book keywords and concepts

Most people are unfamiliar with head and neck cancer, yet it is the fifth most common form of cancer. Patients with head and neck cancer suffer a high mortality rate. Head and neck cancer does not include brain tumors. Treatment includes radiation therapy, which is often implemented following surgery. However, radiation therapy can cause adverse, even lethal, side effects. Lethal radiation necrosis (tissue death) in the brain is one potential side effect of radiation therapy. Also, stroke rates increase by five times in people who have undergone radiation therapy for head and neck cancer.

The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing Gary Null and Amy McDonald See book keywords and concepts

Effect of Oral Zinc Supplementation on Agents of Oropharyngeal Infection in Patients Receiving Radiotherapy for Head and neck cancer. Ertekin MV; Uslu H; et al. Journal of International Medical Research; 2003 July-August, 31(4):253-266. Zinc or placebo was administered to 30 patients who were receiving radiotherapy for head and neck cancer. Findings suggested that some infections with Candida species and staphylococci were prevented by zinc supplementation. Effect of Calcium Ion Uptake on Candida Albicans Morphology. Holmes AR; Cannon RD; Shepherd MG.

You Don't Have to be Afraid of Cancer Anymore Bill Sardi See book keywords and concepts

Journal American College of Nutrition 21: 339-43, 2002] However, a contrary study, widely reported by the news media, indicates high-dose vitamin E (400 IU) combined with radiation treatment for head and neck cancer almost doubled the number of patients likely to develop a new cancer over time. Actually, the percentage of patients that developed a new cancer taking a vitamin E was 23.0%, versus 18.7% among the placebo users, a difference of only 4%. Patients with head and neck cancer have a 60-90% 5-year survival rate, but 15-20% will develop second tumors.

PDR for Herbal Medicines, Fourth Edition Thomson Healthcare, Inc. See book keywords and concepts

A randomized trial of antioxidant vitamins to prevent second primary cancers in head and neck cancer patients. J Natl Cancer Inst; 97(7):481-488. 2005 Benner SE, Winn RJ, Lippman SM et al. Regression of oral leukoplakia with alpha-tocopherol: a Community Clinical Oncology Program Chemoprevention study. J Natl Cancer Inst; 85(l):44-47. 1993 Bjelakovic G, Nagorni A, Nikolova D, et al. Meta-analysis: antioxidant supplements for primary and secondary prevention of colorectal adenoma.

In yet an earlier, multicenter, double-blind, placebo-controlled trial of 540 patients with stage I or II head and neck cancer treated by radiation therapy, those who received vitamin E supplements (400 IU daily) had a higher rate of second primary cancers compared with those receiving placebo. However, upon cessation of treatment with vitamin E, these rates were lower in the group that had received supplementation vs those who had received placebo. Subjects were followed for a median of 52 months.

The Science of Flavonoids Erich Grotewold See book keywords and concepts

Genistein elicits pleiotropic molecular effects on head and neck cancer cells, Clin Cancer Res, 7: 4174-4181. Anderson, J. J., 1999, Plant-based diets and bone health: nutritional implications, Am J Clin Nutr, 70: 539S-542S. Anderson, R. F„ Fisher, L. J., Hara, Y., Harris, T., Mak, W. B., Melton, L. D., and Packer J.E., 2001, Green tea catechins partially protect DNA from (.)OH radical-induced strand breaks and base damage through fast chemical repair of DNA radicals, Carcinogenesis, 22: 1189-1193. Angel, P., and Karin, M.

Feel Better, Live Longer with Vitamin B-3 Dr. Abram Hoffer, MD, FRCP (C) and Dr. Harold D. Foster, PhD See book keywords and concepts

Head and neck cancer. Available from: http://www.obgyn.net/newsrx/general_health-Head_And_Neck_Cancer-20011217-9.asp. Vitamin B-3 Responsive Diseases and Conditions PELLAGRA Prevalence Classical Pellagra Pellagra was known in Europe for near 200 years before being diagnosed in the United States, where it was first identified in 1902. It was initially described by Don Gasper Casal, a physician in the Spanish court. In 1735 Casal noted the illness among poor peasants and called it "mal de la rosa" because all affected patients had a typical reddish glossy rash on their hands and feet.

You Don't Have to be Afraid of Cancer Anymore Bill Sardi See book keywords and concepts

Dietary Supplements: A Framework for Evaluating Safety, Institute of Medicine, National Research Council, 2004] Surprisingly, after years of condemnation by the Food & Drug Administration, a report issued at the International Conference on Head and neck cancer in 2004 by researchers at the Medical University of South Carolina indicates an extract from chaparral seems to be "completely safe as well as beneficial.

The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing Gary Null and Amy McDonald See book keywords and concepts

Zinc or placebo was administered to 30 patients who were receiving radiotherapy for head and neck cancer. Findings suggested that some infections with Candida species and staphylococci were prevented by zinc supplementation. Effect of Calcium Ion Uptake on Candida Albicans Morphology. Holmes AR; Cannon RD; Shepherd MG. Ferns Microbiology Letters, 1991 January 15, 61(2-3):187-193. Calcium was shown to inhibit the growth of Candida albicans yeast cells. Inhibition of Candida adhesion to buccal epithelial cells by an aqueous extract of Allium sativum (garlic). Ghannoum MA.

Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements Phyllis A. Balch, CNC See book keywords and concepts

Also, stroke rates increase by five times in people who have undergone radiation therapy for head and neck cancer. Stroke is the official cause of death among many people who have had head and neck cancer who later die after radiation therapy treatments. For this reason, cancer cure statistics can be misleading. Even though radiation therapy may cure cancer, nonrelated cancer deaths seem to be a long-term side effect to radiation. Although more people with cancer are now living beyond five years after diagnosis, premature death can be direct result of toxic therapies used to eradicate cancer.

You Don't Have to be Afraid of Cancer Anymore Bill Sardi See book keywords and concepts

Nutrition Cancer 26: 11-19, 1996] Antioxidants: Cell protectors Head and neck cancer patients who took 400 units of vitamin E for three years following radiation treatment were at greater risk for secondary tumors (288% increase) compared to patients who did not supplement with vitamin E. [Journal National Cancer Institute 97: 481-88, 2005] This increase in cancer recurrence can be explained by the provision of a sole antioxidant [just vitamin E] rather than a variety of antioxidants, and by the fact that vitamin E is not a selective anti-cancer agent.

Patients with head and neck cancer have a 60-90% 5-year survival rate, but 15-20% will develop second tumors. [Journal National Cancer Institute 97: 481-88, 2005] Vitamin E supplementation didn't significantly change this pattern. Yet the study drew wide attention in the news media. [New York Times, April 12, 2005] Recently The Cancer Treatment Centers of America sponsored a study that conclusively found antioxidant therapy does not interfere with radiation treatment. [3rd Annual Conference, Society for Integrative Oncology, Boston, Nov.

In another study, patients with head and neck cancer were treated with radiation therapy and simultaneously given high-dose vitamin E. The vitamin E caused a higher rate of secondary tumors (288%), but a lower rate when vitamin E was discontinued. [Journal National Cancer Institute 97: 481-88, 2005] This is predictable. The vitamin E should not be given at the same time as radiation treatment. The problem with this type of information is that the public misconstrues what they read and mistakenly conclude that vitamin E causes cancer.

Handbook of Medicinal Plants Amarjit S. Basra See book keywords and concepts

The effect of an adjuvant mistletoe treatment programme in resected head and neck cancer patients: A randomised controlled clinical trial, European Journal of Cancer, 37(1): 23-31. 37. Goebell, P.J., Otto, T., Suhr, J., and Rubben, H., 2002, Evaluation of an unconventional treatment modality with mistletoe lectin to prevent recurrence of superficial bladder cancer: A randomized phase II trial, Journal of Urology, 168(1): 72-75. 38. Stumpf, C, Rosenberger, A., Rieger, S., Troger, W., and Schietzel, M.

Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements Phyllis A. Balch, CNC See book keywords and concepts

We do not recommend that people with head and neck cancer refuse radiation therapy, as it often buys years of extra life. Simply, they should take extra precautions to reduce their risk of stroke. (See under cardiovascular disease in Part Two.) Q A gene linked to the development of colon cancer (when it becomes defective and shuts off in individuals who do not seem to have a family history of the disease) has been identified by researchers at the Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University School of Medicine.

The Side Effects Bible: The Dietary Solution to Unwanted Side Effects of Common Medications Frederic Vagnini, M.D. and Barry Fox, Ph.D. See book keywords and concepts

Amifostine may also encourage the growth of bone marrow in patients with bone marrow diseases and guard against dryness of the mouth in people receiving postsurgical radiation treatment for head and neck cancer. Possible Side Effects The drug's more common side effects include nausea and vomiting (may be severe), low blood pressure, dizziness, flushing, chills, sneezing, and excessive sleepiness.

Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements Phyllis A. Balch, CNC See book keywords and concepts

Stroke is the official cause of death among many people who have had head and neck cancer who later die after radiation therapy treatments. For this reason, cancer cure statistics can be misleading. Even though radiation therapy may cure cancer, nonrelated cancer deaths seem to be a long-term side effect to radiation. Although more people with cancer are now living beyond five years after diagnosis, premature death can be direct result of toxic therapies used to eradicate cancer.

Medical Herbalism: The Science Principles and Practices Of Herbal Medicine David Hoffman, FNIMH, AHG See book keywords and concepts

John's wort Depression Vitamin D Cancer Zinc Head and neck cancer edge the need to apply scientific objectivity in assessing the existing evidence about herbs. If phytotherapy is illuminated with the light of critical evaluation, much of value will be found. WHERE IS THE EVIDENCE? Today, practitioners and consumers alike are being bombarded by claims and counterclaims, information and misinformation about herbs. The confusion is compounded by different, often hidden, agendas.

The Clinician's Handbook of Natural Healing Gary Null, Ph.D. See book keywords and concepts

Results found that patients with single head and neck cancer had lowered levels of beta-carotene and also suggest that low levels of vitamins A and E may be involved in the etiology of second tumors among such patients. —N. de Vries and G.B. Snow, "Vitamin A, Vitamin E and Beta-carotene Serum Levels in Head and neck cancer Patients with andwithout Second Primary Tumors," Third International Head and Neck Oncology Research Conference, September 26-28, 1990, Las Vegas, NV, The American Society for Head and Neck Surgery, A3.1, 1990.

Rational Phytotherapy: A Reference Guide for Physicians and Pharmacists volker schulz and Rudolf Hansel See book keywords and concepts

The effect of an adjuvant mistletoe treatment programme in resected head and neck cancer patients: a randomized controlled clinical trial. Eur J Cancer 37: 23-31. Stimpel M, Proksch A, Wagner H et al (1984) Macrophage activation and induction of macrophage cytotoxicity by purified polysaccharide fractions from the plant Echinacea purpurea. Infect Immunity 46: 845-849. Taylor JA, Weber W, Standish L, et al. (2003) Efficacy and safety of Echinacea in treating upper respiratory tract infections in children. JAMA 290:2824-30.

The Clinician's Handbook of Natural Healing Gary Null, Ph.D. See book keywords and concepts

This study examined the relationships of beta-carotene, vitamin A and vitamin E serum levels in head and neck cancer patients with primary tumors. Results found that patients with single head and neck cancer had lowered levels of beta-carotene and also suggest that low levels of vitamins A and E may be involved in the etiology of second tumors among such patients. —N. de Vries and G.B.

Disease Prevention and Treatment The Life Extension Editorial Staff See book keywords and concepts

These included head and neck cancer patients, healthy volunteers found to have a dietary deficiency of zinc, and healthy volunteers in whom a zinc deficiency was induced by dietary means. Prasad (2000) demonstrated that zinc status affects cytokine levels, but has no effect on the anti-inflammatory cytokines. Production of interleukin-2 and gamma-interferon was decreased even when the zinc deficiency was mild. Natural killer cell activity was also decreased in zinc-deficient subjects. T-cell formation was decreased even in mildly zinc-deficient subjects.

Symptoms: Their Causes & Cures : How to Understand and Treat 265 Health Concerns the Editors of PREVENTION Magazine Health Books See book keywords and concepts

And radiation therapy for head or neck cancer can destroy salivary glands if they're not protected. Symptom Relief -A^Tost treatments for dry mouth require a lot of chewing, Dr. Dodds says. "The more you chew, the more saliva you produce," he explains. "Chewing stimulates the salivary glands, much like exercising a muscle. If you don't use them, they kind of wither away." But those remedies assume you have functioning salivary glands. If the glands don't work, chewing won't help. Crunch a cube. Chewing on crushed ice not only moistens your mouth, says Timothy Durham, D.D.S.

The Clinician's Handbook of Natural Healing Gary Null, Ph.D. See book keywords and concepts

Protective Effects of Vitamin E Against Bleomycin-induced Genotoxicity in Head and neck cancer Patients in Vitro," Anticancer Research, 12(2), March-April 1992, p. 325-327. Results of this study found that 5-fluorouracil treated rats that received supplements of vitamin E showed significantly lower levels liver and plasma lipoperoxide than rats only receiving the anticancer drug. —I.D. Capel, et al., "Vitamin E Retards the Lipoperoxidation Resulting from Anticancer Drug Administration," Anticancer Research, 3(1), January-February 1983, p. 59-62.

Snow, "Vitamin A, Vitamin E and Beta-carotene Serum Levels in Head and neck cancer Patients with andwithout Second Primary Tumors," Third International Head and Neck Oncology Research Conference, September 26-28, 1990, Las Vegas, NV, The American Society for Head and Neck Surgery, A3.1, 1990. This review article makes the following observations with respect to antioxidants and oral cancer prevention: laboratory and animal models have demonstrated beta-carotene and other antioxidant nutrients strongly inhibit oral carcinogenesis.

Cancer Therapy: The Independent Consumer's Guide To Non-Toxic Treatment & Prevention Ralph W. Moss, Ph.D. See book keywords and concepts

Accutane is also being tested in head and neck cancer patients by: Robert Wells Carlson, Stanford University Medical Center Division of Medical Oncology, M-2111,300 Pasteur Drive Stanford, CA 94305. Phone: 415-725-6457 Another Accutane study to establish usefulness of treatment with Accutane on chronic smokers (at least 15 years), excluding women of child-bearing age (under 50). Patients may have had a prior malignancy provided they are currently free of disease. Contact: Waun Ki Hong, University of Texas, M.D.

The Clinician's Handbook of Natural Healing Gary Null, Ph.D. See book keywords and concepts

Snow, "Relationships of Vitamins A and E and Beta-carotene Serum Levels to Head and neck cancer Patients with and without Second Primary Tumors," Eur Arch Otorhinolaryngol, 247(6), 1990, p. 368-370. This review article argues that vitamin E and beta-carotene meet the criteria for an effective chemopreventive agent of oral cancer and it points to the results of eight clinical trials to support this view: —H. Garewal,' 'Chemoprevention of Oral Cancer: Beta-Carotene and Vitamin E in Leukoplakia," European Journal of Cancer Prevention, 3(2), March 1994, p. 101-107.

Noting the radioprotective effect of ascorbic acid patients with head and neck cancer, this paper recommends the oral administration of ascorbic acid for patients suffering from these conditions. —R. Garcia-Alejo Hernandez, et al., [Radioprotective Effect of Ascorbic Acid on Oral Structures in Patients with Cancer of the Head and Neck], Av Odontoestomatol, 5(7), September 1989, p. 469-472. This study found that doses of 2mM of ascorbic acid had a strong cytotoxic effect on neuroblastoma, osteosarcoma, rhabdomyosarcoma and reinoblastoma cells cultured in vitro. Ascorbic acid administered at 0.

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